Product image of Neuroplant Aktiv (St. John´s Wort Dry Extract, Quantified, Der 3-7:1, Extraction Solvent: Methanol 80 % (V/V)) supplied by GNH India

Neuroplant Aktiv

Active Ingredient:
St. John´s Wort Dry Extract, Quantified, Der 3-7:1, Extraction Solvent: Methanol 80 % (V/V)
Origin:
EU

Neuroplant Aktiv (St. John´s Wort Dry Extract, Quantified, Der 3-7:1, Extraction Solvent: Methanol 80 % (V/V))

St. John's Wort, the active ingredient in Neuroplant Aktiv, is a herbal antidepressant presented as a dry extract for oral use. It is used to support mood in adults with mild to moderate depression and related mood disorders.

GNH India supplies Neuroplant Aktiv as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Dr. Willmar Schwabe Gmbh & Co. Kg

1
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Indications & Clinical Uses

Neuroplant Aktiv, a herbal antidepressant, acts on neurotransmitter pathways associated with mood regulation.

  • Mild to moderate depression: helps improve mood and reduce depressive symptoms.
  • Mood disorders: may alleviate emotional instability and low mood.
  • Seasonal affective disorder: supports mood during periods of reduced daylight.

How It Works

  • St. John's Wort dry extract modulates neurotransmitter activity by inhibiting the reuptake of serotonin and influencing dopamine and norepinephrine pathways, leading to increased synaptic concentrations of these mood‑regulating chemicals.

Side Effects

St. John's Wort may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Gastrointestinal upset: nausea, stomach discomfort.
  • Skin reactions: rash, photosensitivity.
  • Fatigue or dizziness: transient feelings of tiredness.
  • Headache: mild to moderate intensity.
  • Insomnia: difficulty falling or staying asleep.

Serious or Rare Side Effects

  • Serotonin syndrome: risk when combined with other serotonergic agents.
  • Severe allergic reaction: anaphylaxis or angioedema.
  • Liver enzyme elevation: potential hepatic involvement.
  • Mood worsening: rare exacerbation of depressive symptoms.
  • Bleeding tendency: increased risk of hemorrhage, especially with anticoagulants.

Precautions & Warnings

When considering Neuroplant Aktiv, several safety measures should be observed.

  • Contraindication: avoid use in patients with known hypersensitivity to Hypericum perforatum.
  • Pregnancy and lactation: safety not established; consult a healthcare professional before use.
  • Drug interactions: review concomitant medications for serotonergic activity.
  • Monitoring: assess mood changes regularly, especially during therapy initiation.
  • Storage: Store below 25°C: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

St. John's Wort interacts with several drug classes, requiring careful management.

Major Interactions (Avoid)

  • SSRIs, SNRIs, MAO inhibitors: risk of serotonin syndrome.
  • Warfarin and other anticoagulants: may reduce anticoagulant effect and increase bleeding risk.
  • Oral contraceptives: can lower hormonal efficacy, leading to unintended pregnancy.

Moderate Interactions (Monitor Closely)

  • Antiepileptic drugs (e.g., carbamazepine, phenytoin): may reduce plasma levels.
  • Immunosuppressants (e.g., cyclosporine): potential decrease in drug exposure.
  • Statins metabolized by CYP3A4: possible reduction in lipid‑lowering effect.

Frequently Asked Questions

Neuroplant Aktiv contains St. John's Wort dry extract and is used as an over‑the‑counter herbal antidepressant to support mood in adults experiencing mild to moderate depression, seasonal affective disorder, or other mood‑related conditions.

The extract modulates neurotransmitter activity by inhibiting serotonin reuptake and influencing dopamine and norepinephrine pathways, which increases the availability of these chemicals in the brain and helps improve mood and emotional balance.

The appropriate dosage of Neuroplant Aktiv is determined by a qualified healthcare professional based on individual needs, clinical condition, and product specifications. Patients should follow the prescriber’s instructions and not self‑adjust the dose.

Safety data for St. John's Wort in pregnancy and lactation are limited. It is recommended that pregnant or nursing women consult their physician before using Neuroplant Aktiv to weigh potential risks and benefits.

Enquiries for Neuroplant Aktiv can be submitted via the product page on gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Unlike synthetic antidepressants, Neuroplant Aktiv is a herbal preparation that primarily influences serotonin reuptake and also affects dopamine and norepinephrine. It may have a more favorable side‑effect profile for some users but can interact with a broader range of medications, requiring careful review.

Neuroplant Aktiv should be stored below 25 °C in its original packaging, protected from moisture and direct sunlight. Keep the product out of reach of children and avoid exposure to extreme temperatures.

Neuroplant Aktiv is taken orally, typically as a tablet or capsule, according to the dosage prescribed by a healthcare professional. It should be swallowed with water and taken with or without food as advised.

The most serious risks include serotonin syndrome when combined with other serotonergic drugs, severe allergic reactions such as anaphylaxis, and potential bleeding complications, especially in patients on anticoagulants.

Individuals with known hypersensitivity to St. John's Wort, those currently taking monoamine oxidase inhibitors, selective serotonin reuptake inhibitors, or other serotonergic agents, and patients with severe liver disease should avoid using Neuroplant Aktiv unless directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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