Product image of Nevolat (Liraglutide) supplied by GNH India

Nevolat

Active Ingredient:
Liraglutide
Origin:
EU

Nevolat (Liraglutide)

Liraglutide, the active ingredient in Nevolat, is a GLP‑1 receptor agonist presented as a subcutaneous injectable for subcutaneous use. It is indicated for the management of type 2 diabetes mellitus and for chronic weight management in adults with obesity. The medication works by enhancing glucose‑dependent insulin secretion and reducing appetite.

GNH India supplies Nevolat as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. Our distribution network ensures product integrity and regulatory compliance across EU and global markets.

Manufacturer / TM Owner

Zentiva, K.S.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Nevolat is a GLP‑1 receptor agonist used in metabolic disease management, targeting glucose regulation and body weight.
  • Type 2 diabetes mellitus: improves glycaemic control by increasing insulin secretion and lowering glucagon levels.
  • Obesity: promotes weight loss through appetite suppression and delayed gastric emptying.
  • Cardiovascular risk reduction: lowers incidence of major adverse cardiovascular events in patients with type 2 diabetes and established cardiovascular disease.

How It Works

  • Liraglutide binds to and activates the glucagon‑like peptide‑1 (GLP‑1) receptor on pancreatic β‑cells, enhancing glucose‑dependent insulin release while inhibiting glucagon secretion. It also slows gastric emptying and acts on hypothalamic centers to reduce appetite, collectively improving glycaemic control and supporting weight reduction.

Side Effects

Common Side Effects

  • Nausea: mild to moderate, often transient.
  • Vomiting: may accompany nausea.
  • Diarrhoea: occasional, usually resolves.
  • Constipation: less frequent.
  • Headache: mild.
  • Injection site reactions: redness or swelling.

Serious or Rare Side Effects

  • Pancreatitis: severe abdominal pain requiring immediate medical attention.
  • Gallbladder disease: cholelithiasis or cholecystitis.
  • Severe hypoglycaemia: especially when combined with insulin or sulfonylureas.
  • Thyroid C‑cell tumours: risk observed in rodent studies.
  • Acute kidney injury: rare, may follow severe gastrointestinal loss.
  • Anaphylaxis: rare allergic reaction.

Precautions & Warnings

Before initiating Nevolat, consider the following precautions:

  • Renal function: assess baseline and monitor periodically.
  • Pancreatitis: discontinue if signs of acute pancreatitis appear.
  • Thyroid disease: avoid in patients with a personal or family history of medullary thyroid carcinoma or MEN2.
  • Pregnancy: use only if potential benefit justifies potential risk to the fetus.
  • Drug interactions: review concomitant medications for hypoglycaemia risk.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Nevolat may interact with several drug classes.

Major Interactions (Avoid)

  • Insulin: increased risk of severe hypoglycaemia.
  • Sulfonylureas: heightened hypoglycaemia potential.
  • Medications causing gastrointestinal irritation: may exacerbate nausea.

Moderate Interactions (Monitor Closely)

  • Warfarin: possible alteration of INR values.
  • Beta‑blockers: may mask hypoglycaemia symptoms.
  • Oral contraceptives: potential reduced efficacy.

Frequently Asked Questions

Nevolat contains liraglutide, a GLP‑1 receptor agonist prescribed to improve blood glucose control in adults with type 2 diabetes and to support chronic weight management in individuals with obesity. It may also be used to lower cardiovascular risk in patients with established disease.

Liraglutide mimics the natural hormone GLP‑1, binding to its receptor on pancreatic beta cells to increase insulin secretion only when glucose levels are high. It simultaneously suppresses glucagon release, slows gastric emptying, and reduces appetite through central nervous system pathways, aiding glycaemic control and weight loss.

The dose of Nevolat is individualized by the prescribing healthcare professional. Initiation typically starts with a low dose that is gradually increased based on tolerability and therapeutic response, following the prescriber’s clinical judgment and local labeling.

Safety data for liraglutide during pregnancy and lactation are limited. It should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.

To request Nevolat, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and import documentation.

Nevolat (liraglutide) shares the class‑wide mechanisms of GLP‑1 agonists but differs in dosing frequency and clinical trial data. Unlike weekly agents such as semaglutide, liraglutide is administered daily, offering more flexible titration. It has robust evidence for both glycaemic control and weight reduction, as well as cardiovascular benefit in high‑risk patients.

Nevolat must be stored in a refrigerator at 2‑8 °C, protected from light. Do not freeze or shake the product. If temporary storage at room temperature is unavoidable, limit exposure to no more than 30 days, then return to refrigeration as soon as possible.

Nevolat is given as a subcutaneous injection, typically in the abdomen, thigh, or upper arm. The injection is performed using a pre‑filled pen or syringe, following the technique and site‑rotation guidelines provided by the prescriber or product label.

Serious adverse events include acute pancreatitis, gallbladder disease, severe hypoglycaemia (especially when combined with insulin or sulfonylureas), and, based on animal data, a potential risk of thyroid C‑cell tumours. Patients should seek immediate medical attention for persistent abdominal pain, severe nausea, or signs of an allergic reaction.

Nevolat is contraindicated in individuals with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia type 2, and in patients with known hypersensitivity to liraglutide or any excipients. Caution is also advised for those with severe renal impairment or a history of pancreatitis.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.