Product image of Nevolat (Liraglutide) supplied by GNH India

Nevolat

Active Ingredient:
Liraglutide
Origin:
EU

Nevolat (Liraglutide)

Liraglutide, the active ingredient in Nevolat, is a GLP‑1 receptor agonist presented as a subcutaneous injection for subcutaneous use. It treats type 2 diabetes mellitus and is also indicated for weight management in adults. The product is authorized in the European Union and conforms to EU pharmaceutical standards, working by enhancing glucose‑dependent insulin secretion, suppressing glucagon, and slowing gastric emptying.

GNH India supplies Nevolat as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with a focus on reliable cold‑chain logistics.

Manufacturer / TM Owner

Zentiva, K.S.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Nevolat (liraglutide) is used in the management of metabolic disorders that involve impaired glucose regulation and excess body weight.

  • Type 2 diabetes mellitus: improves glycemic control and reduces HbA1c levels.
  • Obesity/weight management: promotes weight loss when combined with diet and exercise.
  • Cardiovascular risk reduction: lowers incidence of major adverse cardiovascular events in patients with type 2 diabetes and established cardiovascular disease.

How It Works

  • Liraglutide activates the glucagon‑like peptide‑1 (GLP‑1) receptor on pancreatic β‑cells, which enhances glucose‑dependent insulin secretion, suppresses inappropriate glucagon release, and slows gastric emptying. These actions together improve post‑prandial and fasting blood glucose levels while also promoting satiety, contributing to weight reduction.

Side Effects

Liraglutide may cause a range of adverse reactions, which are categorized by frequency and severity.

Common Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Constipation
  • Headache
  • Injection site reactions (redness, itching)

Serious or Rare Side Effects

  • Pancreatitis
  • Gallbladder disease (cholelithiasis, cholecystitis)
  • Severe hypoglycemia (especially with insulin or sulfonylureas)
  • Acute allergic reactions (anaphylaxis, angioedema)
  • Thyroid C‑cell tumors (observed in rodent studies)
  • Acute renal impairment

Precautions & Warnings

Before initiating Nevolat, clinicians should consider several precautionary measures to ensure safe use.

  • Renal function assessment: evaluate eGFR and adjust use in severe renal impairment.
  • Pancreatitis monitoring: discontinue if signs of pancreatitis develop.
  • Thyroid disease evaluation: avoid in patients with medullary thyroid carcinoma or MEN 2.
  • Gastrointestinal tolerance: start with low dose and titrate to minimize nausea.
  • Pregnancy and lactation: use only if potential benefit justifies potential risk, as safety data are limited.
  • Store at 2-8°C: keep refrigerated, protect from light, do not freeze or shake.

Avoid Interactions

Liraglutide can interact with other medicines, affecting its efficacy or safety.

Major Interactions (Avoid)

  • Concurrent insulin or sulfonylureas: increased risk of severe hypoglycemia.
  • Other GLP‑1 receptor agonists or DPP‑4 inhibitors: additive glucose‑lowering effects.
  • Medications that significantly delay gastric emptying: may alter absorption of oral drugs.

Moderate Interactions (Monitor Closely)

  • Warfarin: possible alteration of INR, monitor coagulation.
  • Oral contraceptives: reduced absorption, consider alternative contraception.
  • Beta‑blockers: may mask hypoglycemia symptoms, monitor blood glucose.
  • Lipid‑lowering agents (statins): monitor for potential changes in lipid profile.

Frequently Asked Questions

Nevolat contains liraglutide, a GLP‑1 receptor agonist indicated for the treatment of type 2 diabetes mellitus to improve blood glucose control, and for chronic weight management in adults when used together with a reduced‑calorie diet and increased physical activity.

Liraglutide binds to and activates the GLP‑1 receptor, which enhances glucose‑dependent insulin secretion, suppresses inappropriate glucagon release, slows gastric emptying, and promotes satiety. These combined actions lower blood glucose levels and support weight loss.

The dose of Nevolat is individualized by the prescribing healthcare professional. Initiation typically starts at a low dose that is gradually increased based on therapeutic response and tolerability, following the prescriber’s clinical judgment.

Safety data for liraglutide in pregnancy and lactation are limited. It should be used only if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision should be made by a qualified healthcare provider.

To order Nevolat, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain logistics if needed), and required import documentation.

Nevolat (liraglutide) shares the core GLP‑1 receptor activation mechanism with other agents in its class, but differences exist in dosing frequency, molecular structure, and clinical trial outcomes. Liraglutide is administered once daily, whereas some alternatives are weekly, and it has demonstrated cardiovascular benefit in specific patient populations.

Nevolat must be stored in a refrigerator at 2‑8 °C, protected from light, and must not be frozen or shaken. If temporary storage at controlled room temperature is unavoidable, it should not exceed 30 °C for more than 14 days, after which any remaining product should be discarded.

Nevolat is supplied as a sterile solution for subcutaneous injection. It is injected into the abdomen, thigh, or upper arm using a pre‑filled pen or syringe, following the injection technique and site‑rotation guidelines provided by the prescribing clinician.

Serious risks include pancreatitis, severe hypoglycemia (especially when combined with insulin or sulfonylureas), gallbladder disease, acute renal impairment, and rare allergic reactions such as anaphylaxis. Patients should be educated to seek immediate medical attention if they experience persistent abdominal pain, vomiting, or signs of an allergic response.

Nevolat is contraindicated in individuals with a personal or family history of medullary thyroid carcinoma, those with multiple endocrine neoplasia type 2 (MEN 2), or patients who have experienced a severe hypersensitivity reaction to liraglutide or any of its excipients.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.