Nex-400 (Naloxone Ampoules) 400mcg/1ml

Nex-400 (Naloxone 400mcg/1ml) is an opioid antagonist ampoule used to reverse opioid overdose effects. It is designed for rapid emergency response in clinical settings. Nex-400 ampoules provide a reliable dose for healthcare professionals. Store at ambient temperature for stability.

Strength

400mcg/1ml

Pack Size

Storage

Ambient

Manufacturer / TM Owner

Neon Laboratories LTD

Select Quantity

Pack/s

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Indications & Clinical Uses

Naloxone is primarily used to reverse the effects of opioid overdose, including respiratory depression. It is commonly administered in emergency situations where opioid toxicity is suspected. Nex-400 ampoules are intended for healthcare professionals to quickly counteract life-threatening opioid-induced symptoms. This medication is not a substitute for emergency medical care but serves as a critical intervention.

Side Effects

Naloxone works by binding to opioid receptors in the brain, displacing opioids and restoring normal breathing. Effects are typically rapid, often within minutes of administration. Patients may experience withdrawal symptoms as opioids are displaced. The duration of action depends on the opioid involved and the dose administered.

Precautions & Warnings

Naloxone should be used with caution in patients with known hypersensitivity to naloxone. It is not a substitute for respiratory support; always ensure airway management is available. Monitor patients closely after administration for recurrence of opioid effects. Nex-400 ampoules should be stored in a cool, dry place away from direct light.

Avoid Interactions

Naloxone may interact with other medications that affect the central nervous system, such as benzodiazepines or alcohol. It can precipitate withdrawal symptoms in patients dependent on opioids. No significant interactions are reported with non-opioid medications. Always inform healthcare providers of all medications being taken.

References

Frequently Asked Questions

Naloxone is used to reverse opioid overdose effects, such as respiratory depression, in emergency situations.

Naloxone typically starts working within minutes of administration, restoring normal breathing.

Naloxone is intended for use by healthcare professionals but may be prescribed for emergency use in some cases.

Common side effects include withdrawal symptoms, nausea, or vomiting as opioids are displaced.

Store naloxone ampoules at ambient temperature, away from direct light and moisture.

Published by GNH India Pharmaceuticals Limited

Last updated: 17 Jun 2026

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