Product image of Nicorette Freshfruit (Nicotine Polacrilex) supplied by GNH India

Nicorette Freshfruit

Active Ingredient:
Nicotine Polacrilex
Origin:
EU

Nicorette Freshfruit (Nicotine Polacrilex)

Nicotine polacrilex, the active ingredient in Nicorette Freshfruit, is a nicotine replacement therapy presented as a chewing gum for oromucosal use. It helps adults who want to quit smoking by reducing withdrawal symptoms and cravings. Nicotine polacrilex works by delivering a controlled dose of nicotine to the oral mucosa, providing a smoother transition away from cigarettes.

GNH India supplies Nicorette Freshfruit as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

Manufacturer / TM Owner

Kenvue Germany Gmbh

1
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Indications & Clinical Uses

Nicotine polacrilex chewing gum is used in nicotine replacement therapy to support smoking cessation.

  • Smoking cessation: provides controlled nicotine to reduce cravings and withdrawal symptoms.
  • Relapse prevention: assists individuals who have quit smoking to maintain abstinence.
  • Reduction of smoking: helps smokers who wish to gradually decrease cigarette consumption.

How It Works

  • Nicotine polacrilex is a nicotine salt that releases nicotine slowly when chewed, allowing absorption through the oral mucosa. The nicotine acts as a partial agonist at nicotinic acetylcholine receptors in the central nervous system, diminishing the intensity of withdrawal symptoms and cravings associated with tobacco cessation while producing fewer reinforcing effects than smoking.

Side Effects

Common Side Effects

  • Mouth irritation or soreness: discomfort in the oral cavity during chewing.
  • Hiccups: involuntary diaphragm contractions after use.
  • Nausea or dyspepsia: mild gastrointestinal upset.
  • Increased salivation: excess saliva production.
  • Jaw discomfort: muscle fatigue from chewing.
  • Bad taste: lingering flavor after use.

Serious or Rare Side Effects

  • Allergic reactions: rash, itching, swelling, or difficulty breathing.
  • Chest pain: unexpected cardiovascular discomfort.
  • Severe dizziness or fainting: notable drop in blood pressure.
  • Persistent vomiting: inability to retain food or fluids.
  • Throat swelling: airway obstruction risk.
  • Anaphylaxis: life‑threatening systemic allergic response.

Precautions & Warnings

Before using Nicotine polacrilex chewing gum, consider the following precautions:

  • Assess nicotine dependence: evaluate the need for nicotine replacement therapy.
  • Allergy check: do not use if known hypersensitivity to nicotine or gum ingredients.
  • Cardiovascular risk: avoid in recent myocardial infarction or unstable angina without medical advice.
  • Dosage limits: do not exceed the recommended chewing frequency advised by a healthcare professional.
  • Pregnancy and breastfeeding: consult a clinician as safety has not been established.
  • Store at room temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Nicotine polacrilex may interact with other medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): increased risk of cardiovascular events.
  • Other nicotine‑containing products: potential nicotine overdose.
  • CYP2A6 inhibitors (e.g., cimetidine): may raise nicotine plasma levels.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: nicotine can affect heart rate and blood pressure.
  • Antihypertensive agents: monitor for changes in blood pressure control.
  • Certain antidepressants (e.g., SSRIs): observe for mood alterations or increased side‑effects.

Frequently Asked Questions

Nicorette Freshfruit is an over‑the‑counter nicotine replacement product designed to help adults who want to quit smoking. By delivering nicotine through a chewing gum, it eases withdrawal symptoms and reduces the urge to smoke, supporting a gradual transition away from cigarettes.

Nicotine polacrilex is a nicotine salt that releases nicotine slowly when the gum is chewed. The nicotine is absorbed through the oral mucosa and acts as a partial agonist at nicotinic acetylcholine receptors in the brain, which lessens cravings and withdrawal while providing a milder stimulant effect than smoking.

The specific dosing regimen for Nicorette Freshfruit is determined by a qualified healthcare professional based on the individual's smoking history, dependence level, and health status. The prescriber will advise how many pieces to chew per day and the timing of each chew.

The safety of nicotine polacrilex in pregnancy or while breastfeeding has not been conclusively established. Women who are pregnant, planning to become pregnant, or nursing should discuss potential risks and benefits with their healthcare provider before using this product.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Nicorette Freshfruit delivers nicotine via a chewing gum, offering flexible dosing and oral absorption, unlike patches that provide steady transdermal delivery or lozenges that dissolve slowly. The gum allows users to control nicotine intake by adjusting chewing frequency, which can be advantageous for those who prefer rapid symptom relief.

Store the gum at room temperature, ideally below 25 °C, in its original packaging. Keep it away from moisture, direct sunlight, and excessive heat to maintain product integrity. Ensure the container is tightly closed after each use to preserve freshness.

The product is taken orally by chewing a piece of gum slowly until a tingling sensation appears, then parking it between the cheek and gum to allow nicotine absorption. Chewing should be intermittent, and the gum should not be swallowed whole.

Serious risks include allergic reactions such as rash, swelling, or anaphylaxis, and cardiovascular events like chest pain or severe dizziness, especially in individuals with underlying heart disease. Users should seek immediate medical attention if any of these symptoms occur.

Individuals with known hypersensitivity to nicotine or any gum ingredients, those who have recently experienced a myocardial infarction or unstable angina without medical clearance, and pregnant or breastfeeding women without professional advice should avoid using this product.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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