Nicorette Menthe Glaciale Sans Sucre (Nicotine)

Nicotine gum is a nicotine replacement therapy used to support smoking cessation by addressing nicotine dependence.

• Smoking cessation: Provides controlled nicotine to lessen withdrawal symptoms and cravings, facilitating gradual reduction of tobacco use.
• Tobacco dependence: Supplies a steady nicotine dose that helps maintain abstinence during the quitting process.
• Nicotine withdrawal: Alleviates acute symptoms such as irritability, anxiety, and difficulty concentrating during the early quit phase.

• Nicotine from the gum is absorbed through the oral mucosa into the bloodstream, where it binds to nicotinic acetylcholine receptors in the central nervous system. This activation mimics the pharmacologic effects of cigarette‑derived nicotine, reducing the intensity of withdrawal and craving while allowing the user to taper nicotine exposure gradually, supporting the cessation of smoking.

Common Side Effects

• Mouth irritation: mild soreness or tingling in the oral cavity.
• Hiccups: transient episodes after chewing.
• Nausea: occasional upset stomach.
• Dyspepsia: indigestion or heartburn.
• Increased salivation: excess saliva production.
• Jaw discomfort: muscle fatigue from chewing.

Serious or Rare Side Effects

• Allergic reaction: rash, itching, or swelling.
• Chest pain: unexplained thoracic discomfort.
• Irregular heartbeat: palpitations or arrhythmia.
• Severe mouth ulcer: persistent ulceration.
• Anaphylaxis: rare, life‑threatening systemic reaction.

Before using nicotine gum, consider the following precautions:

• Assess nicotine dependence level: determine appropriate chewing schedule.
• Allergy check: avoid if known hypersensitivity to nicotine or excipients.
• Cardiovascular status: do not use in recent myocardial infarction or unstable angina unless advised by a physician.
• Frequency limit: do not exceed the recommended number of pieces per day.
• Store at room temperature: keep in the original pack, protect from moisture and direct sunlight.

Nicotine gum may interact with other medicines as follows:

Major Interactions (Avoid)

• Monoamine oxidase inhibitors (MAOIs): risk of hypertensive crisis.
• Insulin: nicotine can affect glucose control, requiring dose adjustments.
• Beta‑blockers: nicotine may diminish therapeutic effect on heart rate.

Moderate Interactions (Monitor Closely)

• Selective serotonin reuptake inhibitors (SSRIs): may increase side‑effect intensity.
• Antihypertensive agents: nicotine can counteract blood‑pressure‑lowering actions.
• Caffeine: combined stimulant effect may increase nervousness or palpitations.