Product image of Nicorette Microtab (Nicotine Betadex) supplied by GNH India

Nicorette Microtab

Active Ingredient:
Nicotine Betadex
Origin:
EU

Nicorette Microtab (Nicotine Betadex)

Nicotine, the active ingredient in Nicorette Microtab, is a nicotine replacement therapy presented as a sublingual tablet for sublingual use. It helps adults who want to quit smoking by reducing withdrawal symptoms and cravings. It is formulated to dissolve quickly under the tongue, delivering a controlled dose of nicotine to the bloodstream without the need for combustion.

GNH India supplies Nicorette Microtab as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies and clinics worldwide. The company adheres to Good Distribution Practice standards and provides regulatory‑approved products to healthcare providers across multiple regions.

Manufacturer / TM Owner

Kenvue France

1
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Indications & Clinical Uses

Nicotine, delivered via Nicorette Microtab, is used in nicotine replacement therapy to support smoking cessation.

  • Smoking cessation: assists adults in quitting tobacco by alleviating withdrawal symptoms.
  • Nicotine withdrawal relief: reduces cravings and discomfort during quit attempts.
  • Adjunct to behavioral counseling: enhances the effectiveness of counseling programs for tobacco dependence.

How It Works

  • Nicotine Betadex acts as an agonist at neuronal nicotinic acetylcholine receptors, especially the α4β2 subtype in the central nervous system. By stimulating these receptors, it triggers dopamine release, mimicking the reinforcing effects of tobacco smoke and thereby diminishing withdrawal sensations and cravings while providing a controlled nicotine dose through sublingual absorption. The sublingual route bypasses first‑pass metabolism, allowing rapid onset of action and steady plasma levels.

Side Effects

Common and rare adverse reactions have been reported with sublingual nicotine tablets.

Common Side Effects

  • Mouth irritation: mild soreness or tingling under the tongue.
  • Nausea: transient feeling of queasiness.
  • Headache: mild to moderate headache.
  • Dizziness: occasional light‑headedness.
  • Hiccups: brief episodes of hiccupping.

Serious or Rare Side Effects

  • Allergic reaction: rash, swelling, or difficulty breathing.
  • Chest pain: unexpected thoracic discomfort.
  • Rapid heart rate: palpitations or tachycardia.

Precautions & Warnings

Before using Nicorette Microtab, consider the following precautions to ensure safe and effective therapy.

  • Medical history: inform healthcare provider of heart disease, hypertension, or diabetes.
  • Pregnancy and lactation: use only if benefits outweigh risks; consult physician.
  • Concurrent nicotine use: avoid using other nicotine products while on therapy.
  • Driving or machinery: be aware of possible dizziness.
  • Store at below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Nicotine may interact with other medicines; be aware of the following potential interactions.

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): may increase hypertensive response.
  • Beta‑blockers: may mask tachycardia signs.

Moderate Interactions (Monitor Closely)

  • CYP2A6 inhibitors (e.g., methoxsalen): may alter nicotine metabolism.
  • Alcohol: can enhance nicotine’s cardiovascular effects.
  • Other nicotine replacement products: risk of nicotine overdose.

Frequently Asked Questions

Nicorette Microtab is an over‑the‑counter nicotine replacement product intended to help adults stop smoking. It provides a controlled sublingual dose of nicotine that eases withdrawal symptoms and reduces cravings, supporting quit‑attempts when used as part of a comprehensive cessation plan.

The nicotine in Nicorette Microtab binds to nicotinic acetylcholine receptors in the brain, especially the α4β2 subtype. This activation releases dopamine and other neurotransmitters, reproducing the rewarding effect of tobacco smoke and thereby lowering the intensity of withdrawal and craving sensations.

The appropriate dosing schedule for Nicorette Microtab is determined by a qualified healthcare professional based on the individual’s smoking history, dependence level, and treatment goals. Patients should follow the prescriber’s instructions and not alter the regimen without medical advice.

Safety data for Nicorette Microtab in pregnancy and lactation are limited. It should only be used if the potential benefit to the mother outweighs any possible risk to the fetus or infant, and this decision must be made in consultation with a physician.

To request Nicorette Microtab, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with nicotine patches or gum, Nicorette Microtab offers rapid sublingual absorption, giving quicker symptom relief. It avoids the need for chewing or wearing a patch, but like all NRTs, it should be matched to patient preference, tolerance, and the overall cessation strategy.

Store Nicorette Microtab at temperatures below 25 °C in its original packaging, protected from moisture and direct sunlight. Keep the tablets out of reach of children and do not use them after the expiry date printed on the label.

Place one tablet under the tongue and allow it to dissolve completely without chewing or swallowing whole. The tablet should remain in place for several minutes to ensure optimal sublingual absorption before swallowing any residual saliva.

Serious adverse events, although rare, include allergic reactions such as rash, swelling or breathing difficulty, chest pain, and rapid heart rate (tachycardia). Users experiencing any of these symptoms should seek immediate medical attention.

Nicorette Microtab is contraindicated in individuals with known hypersensitivity to nicotine or any tablet excipients, and in patients with recent myocardial infarction or unstable angina unless a physician explicitly advises otherwise.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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