Product image of Nicorette (Nicotine Resinate 20%) supplied by GNH India

Nicorette

Active Ingredient:
Nicotine Resinate 20%
Origin:
EU

Nicorette (Nicotine Resinate 20%)

Nicotine, the active ingredient in Nicorette, is a nicotine replacement therapy presented as a 20% w/w oromucosal formulation for oromucosal use. It treats smoking cessation in adult smokers by reducing withdrawal symptoms and cravings.
GNH India supplies Nicorette as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

Manufacturer / TM Owner

Mcneil / Jntl Consumer Health (Finland) Oy

1
Pack/s
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Indications & Clinical Uses

Nicorette is a nicotine replacement product that acts on nicotine dependence to aid cessation of tobacco use.

  • Smoking cessation: helps adult smokers reduce withdrawal symptoms and quit tobacco use.
  • Nicotine dependence: supports reduction of cravings during the quitting process.
  • Tobacco addiction: provides controlled nicotine exposure to facilitate gradual reduction of smoking habit.

How It Works

  • Nicotine Resinate releases nicotine that binds to nicotinic acetylcholine receptors in the central nervous system, partially stimulating these receptors and thereby decreasing the intensity of withdrawal symptoms and cravings associated with abrupt cessation of tobacco smoking.

Side Effects

Nicorette may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Mouth irritation or soreness
  • Nausea or upset stomach
  • Headache
  • Dizziness
  • Hiccups or throat discomfort
  • Insomnia or sleep disturbances

Serious or Rare Side Effects

  • Allergic reaction (rash, swelling, difficulty breathing)
  • Chest pain or palpitations
  • Severe hypertension
  • Irregular heartbeat
  • Persistent vomiting
  • Severe skin reactions such as Stevens‑Johnson syndrome

Precautions & Warnings

Before using Nicorette, consider the following safety measures.

  • Assess nicotine dependence level: determine appropriate duration of therapy.
  • Avoid use in non‑smokers or occasional smokers: risk of nicotine excess.
  • Cardiovascular caution: do not use immediately after recent myocardial infarction or unstable angina.
  • Monitor blood pressure: nicotine can cause transient elevation.
  • Do not exceed recommended treatment duration without medical advice.
  • Store at ambient temperature: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Nicorette can interact with other substances that affect nicotine metabolism or cardiovascular function.

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): may increase risk of hypertension.
  • Concurrent use of other nicotine replacement products: risk of nicotine overdose.

Moderate Interactions (Monitor Closely)

  • Caffeine: may enhance jitteriness or palpitations.
  • Certain antidepressants (e.g., SSRIs): may increase nausea.
  • Beta‑blockers: nicotine‑induced tachycardia may be masked.

Frequently Asked Questions

Nicorette is used as a nicotine replacement therapy to help adult smokers quit tobacco. It provides a controlled dose of nicotine to reduce withdrawal symptoms and cravings, supporting a gradual reduction in cigarette consumption and ultimately achieving smoking cessation.

Nicotine from Nicorette binds to nicotinic acetylcholine receptors in the brain, partially stimulating them. This mimics the effect of nicotine from cigarettes, decreasing the intensity of withdrawal symptoms and cravings while allowing the user to wean off tobacco gradually.

The specific dose and duration of Nicorette therapy are determined by the prescribing healthcare professional based on the individual’s smoking history, nicotine dependence level, and medical condition. Patients should follow the prescriber’s instructions and not alter the regimen on their own.

Safety of Nicorette in pregnancy or while breastfeeding has not been fully established. Women who are pregnant, planning to become pregnant, or nursing should discuss potential risks and benefits with their healthcare provider before using any nicotine replacement product.

To order Nicorette, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Nicorette delivers nicotine via an oromucosal formulation, offering rapid absorption through the oral mucosa. Compared with patches, it provides more flexible dosing and quicker onset, while being similar to gums or lozenges in delivering nicotine without the need for smoking. Choice depends on patient preference and clinical considerations.

Nicorette should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and direct sunlight. Keep the product out of reach of children and do not use it after the expiry date printed on the label.

Nicorette is administered orally by placing the oromucosal formulation in the mouth and allowing it to dissolve slowly, ensuring contact with the oral mucosa. Users should avoid eating or drinking for a few minutes after placement to maximize nicotine absorption.

Serious risks include allergic reactions such as rash, swelling, or difficulty breathing, as well as cardiovascular events like chest pain, palpitations, or severe hypertension. If any of these occur, discontinue use immediately and seek medical attention.

Nicorette should not be used by individuals who are not regular tobacco users, those with recent myocardial infarction or unstable angina, patients with severe hypertension, or anyone who is hypersensitive to nicotine or any excipients in the product. Consultation with a healthcare professional is essential before starting therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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