Product image of Nicorette Spray (Nicotine) supplied by GNH India

Nicorette Spray

Active Ingredient:
Nicotine
Origin:
EU

Nicorette Spray (Nicotine)

Nicotine, the active ingredient in Nicorette Spray, is a nicotinic receptor agonist presented as an oral spray for oromucosal use. It provides rapid, controlled nicotine delivery to alleviate withdrawal symptoms and cravings, supporting adult smokers in their effort to quit tobacco use and maintain abstinence.

GNH India supplies Nicorette Spray as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable global logistics for regulated medicinal products across regulated medicinal products.

Manufacturer / TM Owner

Mcneil Ab

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Nicorette Spray is a nicotine replacement therapy that acts on nicotinic receptors to help manage tobacco dependence.
  • Smoking cessation: assists adult smokers in quitting by reducing withdrawal symptoms and cravings.
  • Nicotine dependence: provides a controlled nicotine dose to lessen the urge to smoke.
  • Relapse prevention: supports maintenance of abstinence after initial quitting.
  • Tobacco use disorder: helps reduce daily cigarette consumption during a quit attempt.
  • Adjunct to behavioral therapy: enhances the effectiveness of counseling programs.

How It Works

  • Nicotine in the spray binds to nicotinic acetylcholine receptors in the central and peripheral nervous system, mimicking the pharmacologic effect of inhaled tobacco smoke. This activation reduces the neuronal deficit caused by nicotine withdrawal, decreasing cravings and alleviating withdrawal symptoms. The oromucosal route allows rapid absorption through the oral mucosa, providing a steadier overall plasma nicotine level compared with smoking.

Side Effects

Nicorette Spray may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Mouth irritation: tingling or burning sensation in the oral cavity.
  • Throat irritation: soreness or scratchy feeling.
  • Nausea: mild stomach upset.

Serious or Rare Side Effects

  • Allergic reaction: rash, itching, swelling, or difficulty breathing.
  • Increased blood pressure: hypertension episodes.
  • Anaphylaxis: life‑threatening systemic reaction.

Precautions & Warnings

  • When using Nicorette Spray, consider the following precautions.
  • Pregnancy: consult a healthcare professional before use.
  • Breastfeeding: discuss potential risks with a doctor.
  • Cardiovascular disease: use with caution due to possible blood pressure effects.
  • Asthma or respiratory conditions: monitor for bronchospasm.
  • Drug interactions: review all concomitant medications with a pharmacist.
  • Store at ambient temperature: keep in original container, protect from moisture and heat.

Avoid Interactions

Nicorette Spray can interact with other medicines; monitor as indicated.

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): may increase hypertensive risk when combined with nicotine.
  • Insulin or oral hypoglycemic agents: nicotine can affect glucose control, requiring dose adjustment.
  • Beta‑blockers: nicotine may mask tachycardia, complicating cardiovascular monitoring.

Moderate Interactions (Monitor Closely)

  • Selective serotonin reuptake inhibitors (SSRIs): monitor for mood changes.
  • Antihypertensive drugs: nicotine may reduce their efficacy, requiring blood pressure checks.

Frequently Asked Questions

Nicorette Spray is an over‑the‑counter nicotine replacement product designed to help adult smokers quit by delivering a measured dose of nicotine through the oral mucosa, thereby reducing cravings and withdrawal symptoms associated with tobacco cessation.

The nicotine in the spray binds to nicotinic acetylcholine receptors in the brain and peripheral nervous system, mimicking the effect of nicotine from cigarettes. This activation lessens the neurochemical deficit that occurs during withdrawal, which in turn diminishes cravings and the urge to smoke.

The specific dosing regimen for Nicorette Spray is determined by a qualified healthcare professional based on the individual’s smoking history, level of dependence, and treatment goals. Patients should follow the prescriber’s instructions and not exceed the recommended number of sprays per day.

Safety data for nicotine oral spray in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their physician before using Nicorette Spray.

To request Nicorette Spray, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with nicotine patches or gum, the spray offers a faster onset of action because nicotine is absorbed directly through the oral mucosa. This can provide quicker relief of cravings, while patches deliver a slower, steady dose and gum requires chewing, which some users find less convenient.

Store Nicorette Spray at ambient temperature, preferably below 25 °C, in its original packaging. Keep the container tightly closed, protect it from moisture and direct sunlight, and keep it out of reach of children.

The spray is used by directing the nozzle toward the inside of the mouth, typically between the cheek and gum, and pressing the actuator to release a measured spray. Users should avoid swallowing immediately and allow the nicotine to absorb through the oral mucosa as instructed by their healthcare provider.

Serious adverse reactions, although rare, include allergic responses such as rash, swelling, or difficulty breathing, significant increases in blood pressure, and anaphylaxis. Any signs of a severe reaction require immediate medical attention.

Individuals with known hypersensitivity to nicotine or any component of the spray, those who are not current smokers, and persons with uncontrolled cardiovascular disease should avoid using Nicorette Spray unless advised otherwise by a qualified healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.