Product image of Nicorettespray (Nicotine) supplied by GNH India

Nicorettespray

Active Ingredient:
Nicotine
Origin:
EU

Nicorettespray (Nicotine)

Nicotine, the active ingredient in Nicorettespray, is a nicotine replacement therapy presented as an oral spray for oromucosal use. It helps adults who are trying to quit smoking by reducing withdrawal symptoms and cravings associated with nicotine dependence. It is available over‑the‑counter and is intended for short‑term use as part of a comprehensive quit‑smoking program.

GNH India supplies Nicorettespray as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, adhering to EU quality standards and providing reliable sourcing for nicotine replacement therapy products.

Manufacturer / TM Owner

Kenvue France

1
Pack/s
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Indications & Clinical Uses

Nicorettespray is a nicotine replacement therapy used to aid smoking cessation.

  • Smoking cessation: reduces nicotine withdrawal symptoms and cravings, facilitating quitting.
  • Tobacco dependence: provides controlled nicotine delivery to replace cigarettes during a quit plan.
  • Relapse prevention: supports maintenance of abstinence by managing occasional urges after initial cessation.

How It Works

  • Nicotine in Nicorettespray acts as an agonist at nicotinic acetylcholine receptors in the central nervous system, particularly the α4β2 subtype. By stimulating these receptors, it mimics the pharmacologic effects of cigarette‑derived nicotine, thereby decreasing the intensity of withdrawal symptoms and reducing the urge to smoke during cessation attempts.

Side Effects

Common Side Effects

  • Mouth irritation: mild soreness or tingling in the oral cavity.
  • Throat irritation: transient scratchy feeling after use.
  • Nausea: occasional upset stomach.
  • Headache: mild to moderate intensity.
  • Dizziness: brief light‑headed sensation.
  • Cough: transient dry cough.

Serious or Rare Side Effects

  • Allergic reaction: rash, swelling, or anaphylaxis.
  • Increased blood pressure: notable rise in systolic/diastolic values.
  • Cardiac arrhythmia: irregular heart rhythm.
  • Severe mouth ulceration: persistent lesions.
  • Respiratory distress: difficulty breathing or wheezing.

Precautions & Warnings

Before using Nicorettespray, consider the following precautions:

  • Assess nicotine dependence level: determine appropriate replacement dose.
  • Allergy check: do not use if hypersensitive to nicotine.
  • Cardiovascular risk: avoid in patients with recent myocardial infarction or unstable angina.
  • Pregnancy and lactation: use only if benefits outweigh potential risks.
  • Dosage limit: do not exceed the prescribed number of sprays per day.
  • Store at room temperature: keep in the original container, protect from moisture and heat.

Avoid Interactions

Nicorettespray may interact with other medicines as follows:

Major Interactions (Avoid)

  • CYP1A2 substrates (e.g., theophylline, clozapine): nicotine induces metabolism, reducing efficacy.
  • Beta‑blockers: nicotine may blunt heart‑rate response.
  • Insulin: nicotine can affect glucose control, requiring dose adjustment.

Moderate Interactions (Monitor Closely)

  • Antidepressants (SSRIs): possible increased side effects such as agitation.
  • Anticoagulants (warfarin): nicotine may alter INR values.
  • Hormonal contraceptives: nicotine may reduce contraceptive effectiveness.

Frequently Asked Questions

Nicorettespray is an oral nicotine spray used as a nicotine replacement therapy to help adults quit smoking. It delivers a controlled dose of nicotine through the mouth, reducing withdrawal symptoms and cravings during a quit‑smoking program.

The nicotine in Nicorettespray binds to nicotinic acetylcholine receptors in the brain, especially the α4β2 subtype. This activation mimics the effect of cigarette‑derived nicotine, easing withdrawal and decreasing the urge to smoke while the user transitions away from cigarettes.

The prescribed dose of Nicorettespray is determined by the treating healthcare professional based on the individual’s smoking habits, nicotine dependence level, and overall health. Patients should follow the prescriber’s instructions and not exceed the recommended number of sprays per day.

Safety data for Nicorettespray in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant, and this decision must be made by a qualified healthcare provider.

To order Nicorettespray, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with nicotine patches or gum, Nicorettespray offers rapid absorption through the oral mucosa, allowing quicker relief of cravings. It also provides flexible dosing, as each spray delivers a precise amount, which can be adjusted more easily than fixed‑dose patches.

Nicorettespray should be stored at room temperature, below 25 °C, in its original packaging. Keep the container tightly closed, protect it from moisture and direct sunlight, and keep it out of reach of children.

The spray is administered orally by directing the nozzle toward the inside of the cheek or under the tongue and pressing the actuator to release a measured spray. The user should avoid swallowing immediately, allowing the nicotine to absorb through the oral mucosa.

Serious risks include allergic reactions such as rash or anaphylaxis, significant increases in blood pressure, cardiac arrhythmias, severe mouth ulceration, and respiratory distress. Any of these symptoms require immediate medical attention.

Nicorettespray should not be used by individuals with known hypersensitivity to nicotine, those who have recently experienced a myocardial infarction or unstable angina, and anyone for whom a healthcare professional determines that the risks outweigh the benefits.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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