Product image of Nicotinamide Sterop (Nicotinamide) supplied by GNH India

Nicotinamide Sterop

Active Ingredient:
Nicotinamide
Origin:
EU

Nicotinamide Sterop (Nicotinamide)

Nicotinamide, the active ingredient in Nicotinamide Sterop, is a Vitamin B3 (niacinamide) presented as a sterile solution for Intramuscular, Intravenous use. It is employed to prevent and treat niacin (vitamin B3) deficiency and to support cellular NAD+ levels in metabolic disorders.
GNH India supplies Nicotinamide Sterop as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratoires Sterop

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Indications & Clinical Uses

Nicotinamide Sterop is used in the management of conditions related to vitamin B3 deficiency and NAD+ metabolism.

  • Niacin deficiency: restores normal levels of vitamin B3 and prevents associated pellagra symptoms.
  • Metabolic disorders: supports NAD+ synthesis, aiding cellular energy metabolism in conditions such as mitochondrial dysfunction.
  • Dermatologic support: may improve skin barrier function in certain skin conditions where niacinamide is indicated.

How It Works

  • Nicotinamide acts as a precursor for nicotinamide adenine dinucleotide (NAD+), a co‑enzyme essential for redox reactions, DNA repair, and cellular signaling. After administration, it is converted intracellularly to NAD+, thereby enhancing metabolic pathways that depend on this co‑factor and supporting normal cellular function.

Side Effects

Nicotinamide Sterop may be associated with a range of adverse reactions following intramuscular or intravenous administration.

Common Side Effects

  • Injection site pain or erythema
  • Mild headache
  • Transient nausea or gastrointestinal discomfort
  • Low‑grade fever
  • Dizziness

Serious or Rare Side Effects

  • Anaphylactic reaction
  • Severe hypotension
  • Stevens‑Johnson syndrome or toxic epidermal necrolysis
  • Significant liver enzyme elevation
  • Hyperuricemia

Precautions & Warnings

When using Nicotinamide Sterop, consider the following safety measures.

  • Assess renal function: adjust use in patients with severe renal impairment.
  • Monitor liver enzymes: watch for hepatic toxicity during prolonged therapy.
  • Evaluate hypersensitivity: discontinue if signs of allergic reaction appear.
  • Use caution in pregnancy: safety data are limited; prescribe only if benefit outweighs risk.
  • Avoid in patients with gout: nicotinamide may increase uric acid levels.
  • Store at ambient temperature: keep in original container, protect from moisture and light.

Avoid Interactions

Nicotinamide may interact with other medicines, requiring attention to potential effects.

Major Interactions (Avoid)

  • Concurrent high‑dose niacin: may exacerbate flushing and hepatotoxicity.
  • Hepatotoxic drugs (e.g., isoniazid, methotrexate): increase risk of liver injury.
  • Anticoagulants (warfarin): may potentiate bleeding risk.

Moderate Interactions (Monitor Closely)

  • Alcohol: can heighten liver enzyme elevations.
  • Antihypertensives: nicotinamide may modestly lower blood pressure.
  • Antidiabetic agents: may affect glucose control.
  • Seizure medications: possible alteration of plasma levels.
  • Oral contraceptives: may increase plasma nicotinamide concentrations.

Frequently Asked Questions

Nicotinamide Sterop is an injectable form of nicotinamide used to prevent and treat vitamin B3 (niacin) deficiency and to support cellular NAD+ levels in metabolic disorders. It may also be employed as an adjunct in certain dermatologic conditions where nicotinamide benefits skin health.

Nicotinamide serves as a precursor for NAD+, a vital co‑enzyme in redox reactions, DNA repair, and cellular signaling. After administration, it is converted to NAD+, enhancing metabolic pathways that rely on this molecule and helping maintain normal cellular function.

The appropriate dose of Nicotinamide Sterop is determined by the prescribing healthcare professional based on the patient’s condition, age, weight, and clinical response. Dosage regimens are individualized and should follow the prescriber’s instructions.

Safety data for Nicotinamide Sterop in pregnancy and lactation are limited. It should be used only if the potential benefit justifies any possible risk to the fetus or infant, and the decision should be made by the treating physician.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including cold‑chain if needed) and import documentation.

Nicotinamide Sterop provides a sterile injectable form of nicotinamide, allowing rapid systemic delivery, whereas oral niacin or nicotinamide tablets are absorbed more slowly and may cause flushing. Injectable nicotinamide avoids the flushing side effect and is useful when oral administration is not feasible.

Store Nicotinamide Sterop at ambient temperature, preferably below 25 °C. Keep the vials in their original packaging, protect them from moisture and direct light, and discard any product that appears discolored or contains particles.

Nicotinamide Sterop is administered by a qualified healthcare professional via intramuscular or intravenous injection. The route, injection site, and infusion rate are selected according to the patient’s clinical needs and the prescriber’s instructions.

Serious risks include anaphylactic reactions, severe hypotension, Stevens‑Johnson syndrome or toxic epidermal necrolysis, significant liver enzyme elevations, and hyperuricemia. Patients should be monitored for any signs of these reactions, and treatment should be stopped immediately if they occur.

Nicotinamide Sterop should be avoided in individuals with known hypersensitivity to nicotinamide or any excipients, in patients with severe hepatic or renal impairment without appropriate monitoring, and in those with a history of severe gout attacks unless benefits outweigh risks.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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