Nicotine Citron Sans Sucre, Édulcorée Au Xylitol Eg Labo (Nicotine)

Nicotine, a nicotine replacement therapy, is used to support smoking cessation by reducing withdrawal symptoms.

• Smoking cessation: helps reduce cravings and withdrawal in adults attempting to quit tobacco.
• Tobacco dependence: provides controlled nicotine to aid transition away from cigarettes.
• Relapse prevention: supports maintenance of abstinence after quitting.
• Craving management: lessens urge to smoke during stressful situations.
• Withdrawal symptom control: mitigates irritability, anxiety, and concentration difficulties.

• Nicotine acts as an agonist at neuronal nicotinic acetylcholine receptors, primarily the α4β2 subtype, producing mild stimulation that mimics the pharmacologic effects of tobacco smoke. This controlled activation reduces the intensity of withdrawal symptoms and cravings, facilitating gradual reduction of nicotine dependence while allowing the user to wean off tobacco.

Nicotine may cause a range of adverse reactions, varying from mild to serious.

Common Side Effects

• Mouth irritation: mild soreness or tingling in the oral cavity.
• Nausea: feeling of queasiness or upset stomach.
• Headache: mild to moderate head pain.
• Dizziness: transient light‑headedness.

Serious or Rare Side Effects

• Cardiovascular events: chest pain, palpitations, or arrhythmia.
• Hypertension: elevated blood pressure.
• Allergic reaction: rash, swelling, or difficulty breathing.
• Seizures: rare convulsive episodes.

When using nicotine buccal products, consider the following precautions to ensure safe use.

• Cardiovascular assessment: evaluate heart disease history before initiating therapy.
• Medical supervision: use under guidance of a healthcare professional.
• Concomitant nicotine: avoid using other nicotine‑containing products simultaneously.
• Recent myocardial infarction: do not use within 2 weeks of a heart attack.
• Children safety: keep out of reach of children and pets.
• Store at ambient temperature: keep in original packaging, protect from moisture and heat.

Nicotine can interact with several medicines; awareness of these interactions helps prevent adverse effects.

Major Interactions (Avoid)

• Other nicotine products: combined use may cause nicotine toxicity.
• Monoamine oxidase inhibitors (MAOIs): may enhance nicotine’s cardiovascular effects.

Moderate Interactions (Monitor Closely)

• Antihypertensive drugs: nicotine may reduce the effectiveness of blood pressure medications.
• Bupropion: concurrent use may increase risk of seizures.
• Caffeine: nicotine can potentiate stimulant effects, leading to increased heart rate.