Nicotinell Anijs (Nicotine Polacrilex)

Nicotinell Anijs is a nicotine replacement product used to address tobacco‑related dependence and support quitting efforts.

• Smoking cessation: assists adult smokers in quitting by reducing cravings and withdrawal symptoms.
• Tobacco dependence: provides a controlled nicotine source to support gradual reduction of tobacco use.
• Relapse prevention: helps maintain abstinence after the initial quitting phase.

• Nicotine Polacrilex is a polymeric resin complex that releases nicotine slowly when placed against the buccal mucosa. The nicotine is absorbed through the oral mucosa into the bloodstream, where it stimulates nicotinic acetylcholine receptors in the central nervous system, mimicking the pharmacologic effects of tobacco smoke and thereby diminishing withdrawal and craving sensations.

Common side effects are generally mild and related to the buccal route of administration.

Common Side Effects

• Mouth irritation: mild soreness or tingling in the oral cavity.
• Throat irritation: occasional scratchy feeling after use.
• Nausea: transient feeling of queasiness.
• Increased salivation: excess saliva production.
• Dyspepsia: mild indigestion or stomach discomfort.
• Hiccups: brief episodes of involuntary diaphragm contraction.

Serious or Rare Side Effects

• Allergic reaction: rash, itching, or swelling that may indicate hypersensitivity.
• Angioedema: rapid swelling of the face, lips, or tongue requiring immediate medical attention.
• Chest pain or arrhythmia: cardiovascular symptoms that should be evaluated promptly.
• Severe mouth ulcer: persistent ulceration beyond normal irritation.
• Anaphylaxis: rare, life‑threatening systemic allergic response.

Before using Nicotinell Anijs, consider the following safety measures.

• Assess nicotine dependence: determine the appropriate level of nicotine replacement.
• Cardiovascular risk: avoid use in patients with recent myocardial infarction or unstable angina.
• Pregnancy and lactation: do not use unless the potential benefit outweighs the risk.
• Duration of therapy: do not exceed the recommended treatment period without medical supervision.
• Concomitant nicotine products: avoid using other nicotine replacement therapies simultaneously.
• Store at ambient temperature: keep in the original packaging, protect from moisture and direct heat.

Nicotinell Anijs may interact with other medicines; awareness of potential interactions helps ensure safe use.

Major Interactions (Avoid)

• Other nicotine replacement products: combined use can lead to nicotine overdose.
• Monoamine oxidase inhibitors (MAOIs): may increase cardiovascular strain.
• Certain antihypertensives: concurrent use may potentiate blood pressure changes.

Moderate Interactions (Monitor Closely)

• CYP2A6 inhibitors: may alter nicotine metabolism and increase systemic exposure.
• Beta‑blockers: nicotine‑induced tachycardia may be masked.
• Alcohol: can enhance nicotine cravings and affect tolerability.