Product image of Nicotinell Cool Mint (Nicotine Polacrilex) supplied by GNH India

Nicotinell Cool Mint

Active Ingredient:
Nicotine Polacrilex
Origin:
EU

Nicotinell Cool Mint (Nicotine Polacrilex)

Nicotine Polacrilex, the active ingredient in Nicotinell Cool Mint, is a nicotine replacement therapy presented as a chewing gum for buccal use. It is intended for adult smokers who are attempting to quit, providing a controlled dose of nicotine to alleviate withdrawal symptoms and reduce cravings associated with tobacco cessation.

GNH India supplies Nicotinell Cool Mint as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring consistent quality, regulatory compliance, and reliable delivery across diverse global markets through a robust supply chain.

Manufacturer / TM Owner

Haleon Belgium

1
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Indications & Clinical Uses

Nicotinell Cool Mint, a nicotine replacement therapy, is used to support smoking cessation.

  • Smoking cessation: helps adult smokers quit by reducing nicotine withdrawal and cravings.
  • Heavy smokers: provides a gradual reduction in nicotine intake to aid transition away from cigarettes.
  • Light smokers: assists in managing mild withdrawal symptoms during quit attempts.

How It Works

  • Nicotine Polacrilex is a nicotine salt bound to an ion‑exchange resin that releases nicotine slowly in the oral cavity. The released nicotine acts as a partial agonist at nicotinic acetylcholine receptors in the central nervous system, producing modest stimulation that mitigates withdrawal symptoms and cravings while allowing the smoker to taper nicotine exposure.

Side Effects

Common Side Effects

  • Mouth irritation: discomfort or soreness in the oral mucosa.
  • Hiccups: transient involuntary diaphragmatic contractions.
  • Nausea: mild upset stomach after chewing.
  • Dyspepsia: indigestion or abdominal discomfort.
  • Increased salivation: excess saliva production.
  • Jaw discomfort: muscle fatigue from chewing.

Serious or Rare Side Effects

  • Allergic reactions: rash, itching, or angioedema.
  • Chest pain: possible cardiac discomfort.
  • Palpitations: irregular or rapid heartbeat.
  • Severe dizziness: marked vertigo or light‑headedness.
  • Throat swelling: potential airway compromise.
  • Anaphylaxis: rare life‑threatening hypersensitivity.

Precautions & Warnings

Before using Nicotinell Cool Mint, consider the following precautions:

  • Assess nicotine dependence: evaluate daily cigarette consumption to select appropriate therapy.
  • Do not exceed recommended chewing frequency: follow prescriber guidance on number of pieces per day.
  • Avoid use in patients with recent myocardial infarction: consult a physician before initiating.
  • Pregnancy and lactation: discuss potential risks with a healthcare provider.
  • Dental conditions: use with caution if oral lesions, ulcers, or recent dental surgery are present.
  • Store at ambient temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Nicotinell Cool Mint may interact with other substances. Monitor as follows:

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): concurrent use may increase cardiovascular stimulation.
  • Other nicotine replacement products: combined use can lead to nicotine overdose.

Moderate Interactions (Monitor Closely)

  • Caffeine: may enhance stimulant effects such as jitteriness.
  • Alcohol: can increase nicotine metabolism, potentially altering efficacy.
  • Certain antihypertensives: monitor blood pressure as nicotine can affect vascular tone.

Frequently Asked Questions

Nicotinell Cool Mint is a nicotine replacement therapy designed to help adult smokers quit by delivering a controlled amount of nicotine through a buccal chewing gum. It reduces withdrawal symptoms and cravings, supporting a gradual transition away from tobacco use.

Nicotine Polacrilex is a nicotine salt bound to an ion‑exchange resin that releases nicotine slowly when the gum is chewed. The nicotine acts as a partial agonist at nicotinic acetylcholine receptors in the brain, providing enough stimulation to lessen withdrawal while allowing the user to taper nicotine exposure.

The exact dosing regimen is determined by the prescribing healthcare professional based on the individual’s smoking history, dependence level, and health status. A prescriber will select the appropriate number of pieces per day and the duration of therapy to match the patient’s quit plan.

Safety data for nicotine polacrilex in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using any nicotine replacement product.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Compared with nicotine patches, the gum provides rapid oral absorption and allows users to titrate nicotine intake by adjusting chewing frequency. Unlike lozenges, the gum offers a longer chewing period, which can help manage cravings more gradually. Choice depends on personal preference, lifestyle, and clinician recommendation.

Store the gum at ambient temperature, ideally below 25 °C, in its original packaging to protect it from moisture and excessive heat. Keep out of reach of children and avoid exposing the product to direct sunlight or humid environments.

The gum is taken buccally. Chew the piece slowly until a mild tingling sensation appears, then park it between the cheek and gum. Repeat chewing intermittently for about 30 minutes, avoiding swallowing the saliva. Do not exceed the number of pieces prescribed per day.

Serious adverse reactions, although rare, include allergic responses such as rash, angioedema, or anaphylaxis, as well as cardiovascular events like chest pain or palpitations. Users should seek immediate medical attention if they experience any signs of a severe allergic reaction or unexplained cardiac symptoms.

Individuals with recent myocardial infarction, uncontrolled hypertension, severe cardiac arrhythmias, or known hypersensitivity to nicotine or any gum ingredients should avoid using Nicotinell Cool Mint. Pregnant or breastfeeding women should only use it after consulting a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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