Product image of Nicotinell Fruit (Nicotine Polacrilex) supplied by GNH India

Nicotinell Fruit

Active Ingredient:
Nicotine Polacrilex
Origin:
EU

Nicotinell Fruit (Nicotine Polacrilex)

Nicotine Polacrilex, the active ingredient in Nicotinell Fruit, is a nicotine replacement therapy presented as a buccal delivery system for buccal use. It is intended to help adults who are trying to quit smoking by providing controlled nicotine exposure to reduce withdrawal symptoms.\n\nGNH India supplies Nicotinell Fruit as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

Manufacturer / TM Owner

Haleon Ireland Limited

1
Pack/s
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Indications & Clinical Uses

  • Nicotinell Fruit, a nicotine replacement therapy, is used to support individuals who are trying to quit tobacco smoking.\n\n- Smoking cessation: helps reduce cravings and withdrawal symptoms associated with quitting smoking, facilitating a gradual reduction in nicotine dependence.\n- Nicotine dependence: provides a controlled source of nicotine to replace cigarettes, allowing users to taper their intake under professional guidance.

How It Works

  • Nicotine Polacrilex is a resin‑bound nicotine complex that releases nicotine slowly when placed in the buccal cavity. The nicotine is absorbed through the oral mucosa, binds to nicotinic acetylcholine receptors in the central nervous system, and partially stimulates these receptors, thereby alleviating withdrawal symptoms and reducing the urge to smoke.

Side Effects

  • Common side effects are generally mild and related to the buccal route of administration.\n\nCommon Side Effects:\n- Mouth irritation: soreness or discomfort in the oral cavity.\n- Nausea: feeling of queasiness after use.\n- Headache: mild to moderate headache episodes.\n- Taste disturbance: altered or unpleasant taste perception.\n\nSerious or Rare Side Effects:\n- Allergic reaction: rash, itching, or swelling that may require medical attention.\n- Throat swelling: significant edema that could affect breathing.\n- Severe mouth ulceration: painful lesions that persist beyond normal use.

Precautions & Warnings

  • Before initiating therapy, consider the following safety measures.\n\n- Assess cardiovascular status: evaluate patient history for recent myocardial infarction or uncontrolled hypertension.\n- Avoid use in recent myocardial infarction: contraindicated in patients with a recent heart attack.\n- Pregnancy and lactation: do not use unless the potential benefit outweighs the risk to the fetus or infant.\n- Monitor for nicotine toxicity: advise patients to report symptoms such as dizziness, rapid heartbeat, or nausea.\n- Store at ambient temperature: keep in the original packaging, protect from moisture and heat.

Avoid Interactions

  • Nicotine can influence the pharmacokinetics or pharmacodynamics of several medicines.\n\nMajor Interactions (Avoid):\n- MAO inhibitors: may increase the risk of hypertensive crisis.\n- Insulin: nicotine may affect glucose control, requiring dose adjustments.\n- Warfarin: nicotine can alter metabolism, potentially affecting anticoagulation.\n\nModerate Interactions (Monitor Closely):\n- Beta‑blockers: nicotine may mask tachycardia, complicating cardiovascular monitoring.\n- CYP1A2 substrates (e.g., theophylline): nicotine induces enzyme activity, possibly reducing drug efficacy.

Frequently Asked Questions

Nicotinell Fruit is an over‑the‑counter nicotine replacement product designed to help adults who want to quit smoking. It delivers nicotine through the buccal mucosa, reducing cravings and withdrawal symptoms associated with tobacco cessation.

Nicotine polacrilex is a resin‑bound nicotine complex that releases nicotine slowly when placed in the mouth. The nicotine is absorbed through the oral lining, binds to nicotinic acetylcholine receptors in the brain, and partially stimulates them, which eases withdrawal and diminishes the urge to smoke.

The specific dosing regimen for Nicotinell Fruit is determined by the prescribing health professional based on the individual’s smoking history, level of dependence, and overall health status. Patients should follow the prescriber’s instructions and not exceed the recommended amount.

The safety of nicotine polacrilex in pregnancy or while breastfeeding has not been definitively established. It should only be used if the potential benefit justifies the possible risk to the fetus or infant, and this decision must be made by a qualified health‑care provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Nicotinell Fruit delivers nicotine via a buccal system, similar to nicotine gum or lozenges, but its resin‑bound formulation provides a steadier release. Compared with patches, it offers more rapid onset and allows users to adjust dosing throughout the day, while still being non‑prescription.

Store Nicotinell Fruit at ambient temperature, below 25 °C, in its original packaging. Keep the product away from moisture, direct sunlight, and excessive heat to maintain its stability and effectiveness.

Place the tablet or lozenge in the mouth and allow it to dissolve slowly between the gum and cheek. Do not chew or swallow whole; the buccal absorption provides the intended nicotine delivery.

Serious risks include allergic reactions such as rash, itching, or swelling, and rare cases of throat edema that could impair breathing. Users should seek immediate medical attention if they experience any signs of a severe allergic response.

Individuals with recent myocardial infarction, uncontrolled hypertension, or known hypersensitivity to nicotine polacrilex should avoid using Nicotinell Fruit. It is also contraindicated in patients for whom nicotine replacement therapy is not appropriate, as determined by a health professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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