Product image of Nicotinell Fruit (Nicotine Polacrilex) supplied by GNH India

Nicotinell Fruit

Active Ingredient:
Nicotine Polacrilex
Origin:
EU

Nicotinell Fruit (Nicotine Polacrilex)

Nicotine Polacrilex, the active ingredient in Nicotinell Fruit, is a nicotine replacement therapy presented as a buccal delivery system for buccal use. It is intended to aid adult smokers in quitting by reducing nicotine withdrawal symptoms and cravings.

GNH India supplies Nicotinell Fruit as a licensed, GDP-compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

Manufacturer / TM Owner

Haleon Spain, S.A.

1
Pack/s
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Indications & Clinical Uses

Nicotinell Fruit is a nicotine replacement product that acts on nicotine dependence to support smoking cessation.

  • Smoking cessation: helps adult smokers quit by alleviating withdrawal symptoms and reducing cravings.
  • Tobacco dependence: assists individuals who wish to cut down on cigarette consumption while transitioning away from smoking.
  • Relapse prevention: provides support for former smokers aiming to maintain long‑term abstinence.

How It Works

  • Nicotine Polacrilex releases nicotine in the oral cavity where it is absorbed through the buccal mucosa. The nicotine binds to nicotinic acetylcholine receptors in the central nervous system, partially stimulating these receptors and thereby diminishing the intensity of withdrawal symptoms and cravings associated with tobacco cessation.

Side Effects

Nicotinell Fruit may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Mouth irritation or soreness
  • Hiccups
  • Nausea
  • Headache
  • Dizziness
  • Throat irritation

Serious or Rare Side Effects

  • Allergic reaction (rash, swelling, difficulty breathing)
  • Oral ulceration or lesions
  • Increased blood pressure or palpitations
  • Chest pain
  • Severe nausea or vomiting
  • Unexplained fainting

Precautions & Warnings

Before using Nicotinell Fruit, consider the following safety measures.

  • Assess nicotine dependence: evaluate smoking history and level of dependence prior to initiation.
  • Avoid use in non‑smokers: not indicated for individuals without nicotine addiction.
  • Monitor cardiovascular status: use with caution in patients with heart disease or hypertension.
  • Do not use with other nicotine products: avoid concurrent use of patches, gum, or e‑cigarettes.
  • Store at ambient temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Nicotinell Fruit can interact with other medicines, requiring attention to avoid adverse outcomes.

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): may increase risk of hypertensive crisis.
  • Strong CYP2A6 inhibitors: can alter nicotine metabolism and increase systemic exposure.

Moderate Interactions (Monitor Closely)

  • Selective serotonin reuptake inhibitors (SSRIs): may heighten nausea.
  • Antihypertensive agents: nicotine may reduce their efficacy.
  • Alcohol: concurrent use can enhance nicotine’s cardiovascular effects.

Frequently Asked Questions

Nicotinell Fruit is an over‑the‑counter nicotine replacement therapy designed to help adult smokers quit. It delivers nicotine through the buccal mucosa, reducing withdrawal symptoms and cravings, thereby supporting smoking cessation and aiding in the transition away from tobacco use.

Nicotine polacrilex is a polymer‑bound nicotine that releases the active compound slowly in the mouth. The nicotine is absorbed through the buccal lining and binds to nicotinic acetylcholine receptors in the brain, providing a controlled stimulus that eases withdrawal and diminishes the urge to smoke.

The appropriate dose is determined by the prescribing health professional based on the individual’s smoking history and dependence level. Clinicians typically start with a dose that matches the smoker’s current nicotine intake and then taper it gradually over time.

Safety data for nicotine polacrilex in pregnancy and lactation are limited, and the product’s pregnancy category is listed as unknown. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and alternatives with their healthcare provider before use.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Nicotinell Fruit provides buccal nicotine delivery, offering a rapid onset similar to nicotine gum but without the need for chewing. Compared with patches, it allows more flexible dosing and quicker tapering. It is an alternative for users who prefer a discreet, non‑chewing option.

Store Nicotinell Fruit at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture, direct sunlight and excessive heat. Do not refrigerate or freeze the tablets, as this could affect their integrity.

Place a tablet or lozenge in the mouth and allow it to dissolve slowly against the buccal mucosa. Do not chew or swallow whole. The nicotine is absorbed through the lining of the cheek, providing a steady release that helps control cravings.

Serious adverse reactions, although rare, include allergic responses such as rash, swelling or difficulty breathing, and severe oral ulceration. Cardiovascular events like increased blood pressure, palpitations or chest pain may also occur, especially in patients with pre‑existing heart conditions.

Nicotinell Fruit is not recommended for non‑smokers, children, or adolescents. Individuals with uncontrolled hypertension, recent myocardial infarction, severe heart disease, or known hypersensitivity to nicotine polacrilex should avoid using this product unless advised otherwise by a clinician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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