Product image of Nicotinell Fruit (Nicotine Polacrilex) supplied by GNH India

Nicotinell Fruit

Active Ingredient:
Nicotine Polacrilex
Origin:
EU

Nicotinell Fruit (Nicotine Polacrilex)

Nicotine Polacrilex, the active ingredient in Nicotinell Fruit, is a nicotine replacement therapy presented as a buccal delivery system for buccal use. It helps adult smokers who wish to quit by supplying controlled nicotine to reduce withdrawal symptoms and cravings.

GNH India supplies Nicotinell Fruit as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies and clinics worldwide. The company adheres to EU quality standards and provides reliable logistics for bulk and individual orders. All shipments are accompanied by full regulatory documentation.

Manufacturer / TM Owner

Reddy Holding Gmbh

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Indications & Clinical Uses

Nicotinell Fruit, a nicotine replacement therapy, is used to aid smoking cessation by delivering nicotine through the buccal mucosa.

  • Smoking cessation: reduces cravings and withdrawal symptoms in adult smokers.
  • Tobacco dependence: supports gradual reduction of nicotine intake.
  • Relapse prevention: helps maintain abstinence after quitting.

How It Works

  • Nicotine Polacrilex is a polymer‑bound nicotine complex that releases nicotine slowly when placed against the buccal mucosa. The liberated nicotine is absorbed through the oral lining, activates nicotinic acetylcholine receptors in the central nervous system, and thereby diminishes withdrawal sensations and craving intensity.

Side Effects

Common Side Effects

  • Mouth irritation: mild soreness or tingling of the oral mucosa.
  • Hiccups: transient episodes during or after use.
  • Nausea: occasional feeling of queasiness.
  • Increased salivation: excess saliva production.

Serious or Rare Side Effects

  • Allergic reaction: rash, itching, or swelling.
  • Angina or arrhythmia: chest pain or irregular heartbeat.
  • Severe hypertension: marked increase in blood pressure.
  • Anaphylaxis: life‑threatening systemic allergic response.
  • Severe mouth ulceration: deep ulcer formation in the oral cavity.

Precautions & Warnings

Before using Nicotinell Fruit, consider the following precautions:

  • Assess nicotine dependence level: determine appropriate strength based on smoking history.
  • Avoid use in recent myocardial infarction: patients with recent heart attack should not use without medical advice.
  • Do not use if allergic to nicotine or excipients: discontinue immediately if hypersensitivity occurs.
  • Monitor blood pressure in hypertensive patients: nicotine can elevate blood pressure.
  • Store at ambient temperature: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Nicotinell Fruit may interact with other medicines as follows:

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): increased risk of hypertensive crisis.
  • Beta‑blockers: nicotine‑induced tachycardia may be masked.
  • CYP2A6 inhibitors: elevated nicotine plasma levels.

Moderate Interactions (Monitor Closely)

  • Alcohol: may enhance nicotine’s cardiovascular effects.
  • Selective serotonin reuptake inhibitors (SSRIs): possible increase in side‑effects.
  • Antihypertensives: nicotine may reduce their efficacy, requiring dose adjustment.

Frequently Asked Questions

Nicotinell Fruit is an over‑the‑counter nicotine replacement therapy designed to help adult smokers quit. It delivers nicotine via the buccal mucosa, which reduces withdrawal symptoms and cravings associated with smoking cessation.

Nicotine polacrilex is a polymer‑bound nicotine complex that releases nicotine slowly when placed against the buccal lining. The nicotine is absorbed through the oral mucosa, activates nicotinic acetylcholine receptors in the brain, and mitigates the physiological and psychological aspects of nicotine withdrawal.

The appropriate dose is determined by the prescribing health‑care professional based on the individual’s smoking history and level of nicotine dependence. The product is typically used several times per day as directed on the label, and patients should follow their clinician’s instructions.

Safety in pregnancy and lactation has not been established; the product is classified as pregnancy category unknown. Use during pregnancy or while breastfeeding should only occur after a thorough discussion with a physician, weighing potential benefits against possible risks to the fetus or infant.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with nicotine gum or transdermal patches, Nicotinell Fruit delivers nicotine through a buccal polymer matrix, offering a steadier release and potentially fewer dosing fluctuations. Choice of product depends on patient preference, tolerability, and clinical guidance from a health‑care professional.

Store the product at ambient temperature below 25 °C in its original packaging, protected from moisture and direct sunlight. Keep it out of reach of children and do not use it after the expiry date indicated on the label.

Place the product in the mouth and position it against the buccal mucosa, allowing the nicotine‑polacrilex complex to release nicotine. Do not chew or swallow the product whole; follow the package instructions for the duration of each use.

Serious adverse reactions, although rare, can include allergic responses such as rash or swelling, angina, arrhythmias, significant hypertension, severe mouth ulceration, and anaphylaxis. Any signs of cardiovascular distress or hypersensitivity require immediate medical attention.

Individuals with known hypersensitivity to nicotine or any excipients, those who have experienced a recent myocardial infarction, patients with uncontrolled hypertension, and persons taking monoamine oxidase inhibitors should avoid using Nicotinell Fruit unless advised otherwise by a qualified health‑care professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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