Product image of Nicotinell Icemint (Nicotine Polacrilex) supplied by GNH India

Nicotinell Icemint

Active Ingredient:
Nicotine Polacrilex
Origin:
EU

Nicotinell Icemint (Nicotine Polacrilex)

Nicotine Polacrilex, the active ingredient in Nicotinell Icemint, is a nicotine replacement therapy presented as a chewing gum for buccal use. It delivers controlled nicotine to the oral mucosa, helping adult smokers who are motivated to quit by reducing withdrawal symptoms and cravings associated with nicotine cessation.

GNH India supplies Nicotinell Icemint as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies and clinics worldwide. The product complies with EU regulatory standards and is available for distribution to healthcare providers across multiple regions.

Manufacturer / TM Owner

Reddy Holding Gmbh

1
Pack/s
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Indications & Clinical Uses

Nicotinell Icemint, a nicotine replacement therapy, is used to aid smoking cessation in adults.

  • Smoking cessation: helps reduce nicotine withdrawal and cravings during quit attempts.
  • Tobacco dependence: supports gradual reduction of nicotine intake for individuals seeking to quit smoking.

How It Works

  • Nicotine Polacrilex is a resin‑bound nicotine complex that releases nicotine slowly when chewed. The nicotine is absorbed through the buccal mucosa, binding to nicotinic acetylcholine receptors in the brain, which mitigates the neurochemical deficits that cause withdrawal symptoms and cravings during nicotine abstinence.

Side Effects

Nicotinell Icemint may cause a range of adverse reactions. Most are mild and resolve with continued use or after discontinuation.

Common Side Effects

  • Mouth irritation: soreness or discomfort in the oral cavity.
  • Hiccups: involuntary diaphragm spasms.
  • Nausea: feeling of queasiness or upset stomach.
  • Dyspepsia: indigestion or heartburn.
  • Increased salivation: excess saliva production.
  • Throat irritation: scratchy or sore throat.

Serious or Rare Side Effects

  • Allergic reaction: rash, itching, swelling, or difficulty breathing.
  • Chest pain: unexpected discomfort in the chest area.
  • Irregular heartbeat: palpitations or arrhythmia.
  • Severe dizziness: feeling of light‑headedness or loss of balance.
  • Swallowing difficulties: trouble swallowing or feeling of blockage.
  • Persistent vomiting: ongoing emesis that does not resolve.

Precautions & Warnings

Before using Nicotinell Icemint, consider the following safety measures.

  • Cardiovascular assessment: evaluate heart disease or hypertension before initiating therapy.
  • Follow dosing instructions: use only as directed by a healthcare professional.
  • Non‑smoker restriction: do not use if you have never smoked regularly.
  • Avoid excessive chewing: do not chew longer than recommended to prevent nicotine overdose.
  • Keep out of reach of children: store securely to prevent accidental ingestion.
  • Store at ambient temperature: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Nicotinell Icemint can interact with other medications or substances. Review the following categories.

Major Interactions (Avoid)

  • Other nicotine products: concurrent use may lead to nicotine toxicity.
  • Monoamine oxidase inhibitors (MAOIs): increased risk of hypertensive episodes.
  • Certain antidepressants (e.g., bupropion): heightened seizure risk.

Moderate Interactions (Monitor Closely)

  • Caffeine: may amplify stimulant effects such as jitteriness.
  • Warfarin: nicotine can affect clotting parameters; monitor INR.
  • Insulin or oral hypoglycemics: nicotine may alter blood glucose control.
  • Beta‑blockers: nicotine‑induced tachycardia may be masked.
  • Antipsychotics metabolized by CYP2D6: nicotine can induce enzyme activity, reducing drug levels.

Frequently Asked Questions

Nicotinell Icemint is a nicotine replacement therapy in chewing‑gum form that helps adult smokers reduce withdrawal symptoms and cravings while they attempt to quit smoking. It is intended for short‑term use as part of a comprehensive smoking‑cessation program.

Nicotine polacrilex is a resin‑bound nicotine complex that releases nicotine gradually when the gum is chewed. The nicotine is absorbed through the buccal mucosa and binds to nicotinic acetylcholine receptors in the brain, decreasing the neurochemical drive that produces withdrawal and cravings.

The specific dosing regimen is set by the prescribing healthcare professional based on the individual’s smoking history and dependence level. Typical regimens involve chewing a defined number of pieces per day, but the exact schedule should be confirmed with the prescriber.

Safety data for nicotine polacrilex in pregnancy and lactation are limited, and the product is classified as having an unknown pregnancy category. Women who are pregnant, planning pregnancy, or breastfeeding should discuss potential risks with their healthcare provider before using the gum.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Compared with nicotine patches or lozenges, Nicotinell Icemint provides rapid nicotine delivery through the oral mucosa, allowing users to control intake by adjusting chewing frequency. This can be advantageous for managing sudden cravings, while patches offer steadier plasma levels. Choice depends on personal preference, smoking pattern, and clinician recommendation.

Store the gum at ambient temperature, preferably below 25 °C, in its original packaging to protect it from moisture and direct sunlight. Keep the product out of reach of children and do not use if the packaging is damaged or the gum appears discolored.

Place a piece of gum between the cheek and gum, chew slowly until a peppery taste develops, then park the gum between the cheek and gum to allow nicotine absorption. Repeat the chew‑park cycle for about 30 minutes, then discard the gum. Follow the prescriber’s instructions for frequency.

Serious adverse events, though rare, include allergic reactions such as rash, swelling, or difficulty breathing, as well as chest pain, irregular heartbeat, severe dizziness, persistent vomiting, and swallowing difficulties. Any of these symptoms require immediate medical attention.

Individuals who have never smoked regularly, those with known hypersensitivity to nicotine or any gum ingredients, patients with recent myocardial infarction or uncontrolled hypertension, and persons using other nicotine‑containing products should avoid using Nicotinell Icemint unless directed by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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