Product image of Nicotinell Icemint (Nicotine Polacrilex) supplied by GNH India

Nicotinell Icemint

Active Ingredient:
Nicotine Polacrilex
Origin:
EU

Nicotinell Icemint (Nicotine Polacrilex)

Nicotine Polacrilex, the active ingredient in Nicotinell Icemint, is a nicotine replacement therapy presented as a lozenge for buccal use. It treats smoking cessation in adult smokers who wish to quit nicotine dependence.
GNH India supplies Nicotinell Icemint as a licensed, GDP-compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

Manufacturer / TM Owner

Dr. Reddy's Laboratories (Uk) Ltd

1
Pack/s
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Indications & Clinical Uses

Nicotinell Icemint is a nicotine replacement therapy that addresses nicotine dependence and supports quitting smoking.

  • Smoking cessation: helps adult smokers reduce cravings and withdrawal symptoms when quitting tobacco.
  • Nicotine dependence: provides controlled nicotine delivery to lessen physiological dependence.
  • Relapse prevention: assists individuals who have quit to maintain abstinence by managing occasional urges.

How It Works

  • Nicotine Polacrilex is a nicotine ion‑exchange resin that releases nicotine slowly in the oral cavity. The nicotine is absorbed through the buccal mucosa, stimulating nicotinic acetylcholine receptors in the brain, which mimics the pharmacologic effect of cigarette smoking and thereby reduces withdrawal symptoms and cravings associated with cessation.

Side Effects

Nicotinell Icemint may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Mouth irritation: mild soreness or tingling in the oral cavity.
  • Nausea: occasional feeling of queasiness.
  • Headache: mild to moderate tension‑type headache.
  • Dyspepsia: indigestion or stomach discomfort.
  • Increased salivation: temporary excess saliva production.

Serious or Rare Side Effects

  • Cardiovascular events: chest pain, palpitations, or hypertension.
  • Severe allergic reaction: rash, itching, swelling, or difficulty breathing.
  • Persistent dizziness or fainting.
  • Gastrointestinal ulceration or bleeding.
  • Uncontrolled hypertension in susceptible individuals.

Precautions & Warnings

Before using Nicotinell Icemint, consider the following safety measures.

  • Cardiovascular disease: use with caution if you have heart disease or hypertension.
  • Pregnancy and lactation: consult a healthcare professional before use.
  • Diabetes: monitor blood glucose as nicotine may affect glycemic control.
  • Concomitant nicotine products: avoid using other nicotine replacement therapies simultaneously.
  • Storage: Store at ambient temperature below 25°C: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Nicotinell Icemint can interact with certain medications, requiring attention to dosage and monitoring.

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): may increase risk of hypertensive crisis.
  • Beta‑blockers: nicotine may blunt therapeutic response.

Moderate Interactions (Monitor Closely)

  • Antidepressants (SSRIs, SNRIs): nicotine may alter plasma levels.
  • Antidiabetic agents: nicotine can affect glucose metabolism.
  • Caffeine‑containing products: may enhance stimulant effects.
  • Other nicotine replacement products: risk of nicotine overdose.

Frequently Asked Questions

Nicotinell Icemint is an over‑the‑counter nicotine replacement therapy formulated as a lozenge. It is used to help adult smokers quit tobacco by delivering nicotine through the buccal mucosa, thereby reducing cravings and withdrawal symptoms associated with smoking cessation.

Nicotine polacrilex is a resin‑bound form of nicotine that releases the drug slowly when the lozenge dissolves in the mouth. The released nicotine is absorbed across the buccal lining, activates nicotinic acetylcholine receptors in the brain, and mimics the stimulant effect of smoking, which eases withdrawal and craving.

The specific dosing regimen for Nicotinell Icemint is determined by the prescribing healthcare professional based on the individual’s smoking history, level of dependence, and treatment goals. The prescriber will advise the number of lozenges per day and the duration of therapy.

Safety data for nicotine polacrilex in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Nicotinell Icemint.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Nicotinell Icemint delivers nicotine via buccal absorption, offering a slower, steadier release compared with nicotine gum, which requires chewing, and nicotine patches, which provide transdermal delivery. The lozenge can be convenient for users who prefer a discreet, oral option and who may experience less oral irritation than gum.

Store the lozenges at ambient temperature below 25 °C, in the original packaging, protected from moisture, heat, and direct sunlight. Keep out of reach of children and do not use if the package is damaged or the lozenges appear discolored.

Place one lozenge in the mouth and allow it to dissolve slowly without chewing or swallowing whole. Avoid eating or drinking for at least 15 minutes after the lozenge has dissolved to ensure optimal nicotine absorption through the buccal mucosa.

Serious adverse reactions, although rare, include cardiovascular events such as chest pain or hypertension, severe allergic reactions (rash, swelling, difficulty breathing), and gastrointestinal ulceration or bleeding. Users should seek immediate medical attention if any of these symptoms occur.

Individuals with known hypersensitivity to nicotine polacrilex or any component of the lozenge should avoid use. It is also contraindicated in patients with recent myocardial infarction, uncontrolled hypertension, or those currently using other nicotine replacement products without medical supervision.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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