Product image of Nicotinell Lakrids (Nicotine Polacrilex) supplied by GNH India

Nicotinell Lakrids

Active Ingredient:
Nicotine Polacrilex
Origin:
EU

Nicotinell Lakrids (Nicotine Polacrilex)

Nicotine Polacrilex, the active ingredient in Nicotinell Lakrids, is a nicotine replacement therapy presented as a buccal lozenge for buccal use. It helps adult smokers manage nicotine withdrawal and reduce cravings during cessation attempts.

GNH India supplies Nicotinell Lakrids as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory‑approved batches to meet global demand. Clients benefit from reliable delivery timelines, comprehensive documentation, and dedicated technical support throughout the procurement process.

Manufacturer / TM Owner

Reddy Holding Gmbh

1
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Indications & Clinical Uses

Nicotinell Lakrids, a nicotine replacement therapy, is used to address nicotine dependence and related withdrawal symptoms.

  • Smoking cessation: assists adult smokers in quitting by supplying controlled nicotine to reduce cravings.
  • Nicotine withdrawal management: alleviates symptoms such as irritability, anxiety, and difficulty concentrating during quit attempts.
  • Harm reduction: provides a less harmful nicotine source for smokers seeking to lower cigarette consumption.

How It Works

  • Nicotine Polacrilex is a resin‑bound nicotine complex that releases nicotine gradually when placed in the mouth. The nicotine is absorbed through the buccal mucosa into the bloodstream, where it binds to nicotinic acetylcholine receptors in the central nervous system. This receptor activation mimics the effect of cigarette‑derived nicotine, reducing withdrawal intensity and craving while allowing the smoker to taper nicotine exposure over time.

Side Effects

Nicotinell Lakrids may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Mouth irritation: mild soreness or tingling in the oral cavity.
  • Nausea: feeling of queasiness after lozenge use.
  • Hiccups: involuntary diaphragm contractions.
  • Dyspepsia: indigestion or stomach discomfort.
  • Increased salivation: excess saliva production.

Serious or Rare Side Effects

  • Allergic reaction: rash, itching, swelling, or difficulty breathing.
  • Chest pain: unexpected thoracic discomfort that may indicate cardiovascular stress.
  • Severe mouth ulceration: large or persistent ulcer in the oral mucosa.

Precautions & Warnings

Before using Nicotinell Lakrids, consider the following precautions to ensure safe and effective use.

  • Assess nicotine dependence: evaluate smoking history and level of addiction.
  • Use as directed: follow prescriber instructions regarding frequency and duration.
  • Contraindicated in recent myocardial infarction: avoid use within 2 weeks of a heart attack.
  • Not for non‑smokers or occasional smokers: product is intended for regular tobacco users.
  • Keep out of reach of children: accidental ingestion can cause nicotine toxicity.
  • Store at ambient temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Nicotinell Lakrids can interact with certain medicines; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Other nicotine replacement products: concurrent use may lead to nicotine overdose.
  • Monoamine oxidase inhibitors (MAOIs): combined use can increase cardiovascular effects.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: nicotine may diminish blood‑pressure‑lowering effect.
  • Antidepressants (SSRIs): nicotine can alter plasma levels, requiring monitoring.
  • Antidiabetic drugs: nicotine may affect blood glucose control.

Frequently Asked Questions

Nicotinell Lakrids is a nicotine replacement therapy designed to help adult smokers quit or reduce cigarette use. It supplies a controlled amount of nicotine through the buccal mucosa, easing withdrawal symptoms and cravings associated with smoking cessation.

Nicotine Polacrilex is a resin‑bound nicotine complex that releases nicotine slowly when the lozenge is placed in the mouth. The nicotine is absorbed through the buccal lining, reaches the brain, and activates nicotinic acetylcholine receptors, mimicking the effect of smoked nicotine and reducing withdrawal.

The appropriate dose of Nicotinell Lakrids is determined by a qualified prescriber based on the individual’s smoking history, level of dependence, and health status. Patients should follow the healthcare professional’s instructions regarding the number of lozenges per day and the duration of therapy.

The safety of Nicotinell Lakrids in pregnancy or while breastfeeding has not been definitively established. Healthcare providers generally recommend avoiding nicotine replacement products during pregnancy unless the benefits outweigh potential risks, and they should be used with caution in lactating women.

To order Nicotinell Lakrids, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Nicotinell Lakrids offers buccal delivery of nicotine in a lozenge form, which can be convenient for users who prefer not to use patches or inhalers. Compared with patches, lozenges provide faster onset of action, while inhalers may more closely mimic the hand‑to‑mouth ritual of smoking. Choice depends on personal preference, lifestyle, and clinical guidance.

Nicotinell Lakrids should be stored at ambient temperature, below 25 °C, in its original packaging. Protect the lozenges from moisture, direct sunlight, and excessive heat to maintain product stability and potency throughout its shelf life.

The lozenge is placed in the mouth and allowed to dissolve slowly, without chewing or swallowing whole. Users should avoid eating or drinking for at least 15 minutes after the lozenge has dissolved to ensure optimal nicotine absorption through the buccal mucosa.

Serious risks include allergic reactions such as rash, swelling, or difficulty breathing, and cardiovascular events like chest pain or palpitations. If any of these symptoms occur, the user should discontinue the product immediately and seek medical attention.

Nicotinell Lakrids should not be used by individuals who are not regular smokers, those who have had a recent myocardial infarction (within the past two weeks), pregnant or breastfeeding women unless advised by a healthcare professional, and anyone with known hypersensitivity to nicotine or the lozenge excipients.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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