Product image of Nicotinell Lakrits (Nicotine Polacrilex) supplied by GNH India

Nicotinell Lakrits

Active Ingredient:
Nicotine Polacrilex
Origin:
EU

Nicotinell Lakrits (Nicotine Polacrilex)

Nicotine polacrilex, the active ingredient in Nicotinell Lakrits, is a nicotine replacement therapy presented as a buccal delivery system for buccal use. It helps adults who smoke to manage withdrawal symptoms and cravings during cessation attempts.

GNH India supplies Nicotinell Lakrits as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies and clinics worldwide.

Manufacturer / TM Owner

Reddy Holding Gmbh

1
Pack/s
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Indications & Clinical Uses

Nicotinell Lakrits is a nicotine replacement therapy that addresses nicotine dependence and supports quitting smoking.

  • Smoking cessation: reduces withdrawal symptoms and cravings, facilitating a smoother transition to a smoke‑free life.
  • Tobacco dependence: provides controlled nicotine exposure to lessen the urge to smoke.
  • Relapse prevention: helps maintain abstinence by delivering steady nicotine levels during high‑risk periods.

How It Works

  • Nicotine polacrilex releases nicotine through buccal absorption, where the nicotine binds to nicotinic acetylcholine receptors in the central nervous system. This partial stimulation reduces the intensity of withdrawal symptoms and cravings associated with nicotine deprivation, allowing the user to gradually wean off tobacco smoking while maintaining a level of nicotine satisfaction.

Side Effects

Nicotinell Lakrits may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Mouth irritation: mild soreness or tingling at the site of placement.
  • Nausea: occasional upset stomach or feeling of queasiness.
  • Headache: mild to moderate head discomfort.
  • Dizziness: transient light‑headedness.
  • Increased salivation: excess saliva production.
  • Indigestion: mild heartburn or dyspepsia.

Serious or Rare Side Effects

  • Allergic reaction: rash, itching, swelling, or difficulty breathing.
  • Persistent throat irritation: severe or prolonged soreness.
  • Cardiovascular events: chest pain or palpitations (rare).
  • Severe nausea/vomiting: uncontrollable episodes.
  • Hypotension: unusually low blood pressure.
  • Stevens‑Johnson syndrome: rare severe skin reaction.

Precautions & Warnings

Before using Nicotinell Lakrits, consider the following safety measures.

  • Cardiovascular disease: consult a healthcare professional if you have heart conditions.
  • Pregnancy: discuss risks with a physician before use.
  • Breastfeeding: seek medical advice regarding exposure to the infant.
  • Pediatric use: not recommended for children under 18 years.
  • Concomitant nicotine products: avoid using other nicotine sources simultaneously.
  • Storage: Store below 25°C: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Nicotinell Lakrits can interact with certain medications and substances.

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): may increase hypertensive risk.
  • Certain antihypertensives: nicotine can counteract blood‑pressure‑lowering effects.

Moderate Interactions (Monitor Closely)

  • Caffeine: nicotine may enhance stimulant effects, leading to jitteriness.
  • Antidepressants (SSRIs, SNRIs): monitor for increased anxiety or insomnia.
  • Antipsychotics: nicotine may alter plasma levels, requiring dose adjustment.
  • Alcohol: combined use can increase cardiovascular strain.
  • Herbal supplements (e.g., St. John’s wort): may affect nicotine metabolism.

Frequently Asked Questions

Nicotinell Lakrits is an over‑the‑counter nicotine replacement therapy designed to help adults who smoke manage withdrawal symptoms and cravings during a quit attempt. It delivers nicotine through the buccal mucosa, providing a controlled dose that reduces the urge to smoke and supports smoking cessation.

Nicotine polacrilex is a polymer‑bound nicotine that releases the active ingredient slowly when placed against the cheek. The nicotine is absorbed through the buccal lining, binds to nicotinic acetylcholine receptors in the brain, and partially stimulates them. This mimics the effect of smoking enough to lessen cravings while allowing the user to taper nicotine exposure over time.

The appropriate dose of Nicotinell Lakrits is determined by the prescribing healthcare professional based on the individual’s smoking history, level of dependence, and treatment goals. Patients should follow the prescriber’s instructions and not exceed the recommended number of tablets per day.

Safety data for nicotine polacrilex in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks and benefits with their healthcare provider before using Nicotinell Lakrits. The prescriber may recommend alternative cessation strategies if concerns arise.

To order Nicotinell Lakrits, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, and will request verification of trade or institutional credentials. After confirmation, the team provides pricing, availability, shipping details, and any necessary import documentation.

Nicotinell Lakrits delivers nicotine via a buccal tablet, offering a discreet, non‑inhaled option compared with patches, gums, or lozenges. Its polymer‑bound nicotine provides a steady release, which can result in fewer spikes in nicotine levels than some gums or lozenges. Choice of product depends on patient preference, tolerability, and specific cessation plan.

Nicotinell Lakrits should be stored below 25 °C in its original packaging, protected from moisture and direct sunlight. Keep the product out of reach of children and avoid exposing it to extreme temperatures, which could affect tablet integrity and nicotine stability.

The tablet is placed between the gum and cheek, allowing it to dissolve slowly. Users should avoid chewing or swallowing the tablet whole. The tablet should remain in place until it has fully dissolved, typically a few minutes, after which the user can replace it with a new one as directed by the prescriber.

Serious risks, though rare, include allergic reactions such as rash, swelling, or difficulty breathing, and cardiovascular events like chest pain or palpitations. Users should seek immediate medical attention if they experience any signs of a severe allergic response or persistent chest discomfort while using the product.

Nicotinell Lakrits is not recommended for individuals under 18 years of age, those with known hypersensitivity to nicotine polacrilex or any tablet excipients, and patients with recent myocardial infarction or uncontrolled severe cardiovascular disease unless advised otherwise by a healthcare professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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