Product image of Nifedipina Alter (Nifedipine) supplied by GNH India

Nifedipina Alter

Active Ingredient:
Nifedipine
Origin:
EU

Nifedipina Alter (Nifedipine)

Nifedipine, the active ingredient in Nifedipina Alter, is a calcium channel blocker presented as a tablet for oral use. It is used to manage high blood pressure, relieve chest pain from angina, and improve blood flow in Raynaud's phenomenon, primarily in adult patients.
GNH India supplies Nifedipina Alter as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Alter S.A.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Nifedipine acts on the cardiovascular system by relaxing vascular smooth muscle, which is useful in several related conditions.
  • Hypertension: lowers blood pressure by reducing peripheral vascular resistance.
  • Chronic stable angina: decreases myocardial oxygen demand and alleviates chest pain.
  • Raynaud's phenomenon: improves peripheral blood flow, reducing episodes of vasospasm.

How It Works

  • Nifedipine selectively inhibits L‑type calcium channels in vascular smooth muscle and cardiac myocytes. By blocking calcium influx, it prevents contraction of arterial smooth muscle, causing vasodilation and reduced systemic vascular resistance, while also decreasing myocardial contractility and oxygen consumption, which together lower blood pressure and relieve anginal symptoms.

Side Effects

Nifedipine may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Headache: often mild and transient.
  • Flushing: warmth and redness of the skin.
  • Peripheral edema: swelling of the ankles or feet.
  • Dizziness or light‑headedness, especially on standing.
  • Nausea or abdominal discomfort.
  • Gingival hyperplasia: overgrowth of gum tissue.

Serious or Rare Side Effects

  • Severe hypotension: marked drop in blood pressure.
  • Myocardial infarction: rare but reported in high‑risk patients.
  • Atrioventricular block: conduction abnormalities.
  • Hepatotoxicity: liver enzyme elevations.
  • Severe allergic reactions: rash, swelling, or anaphylaxis.
  • Thrombocytopenia: low platelet count.

Precautions & Warnings

Before prescribing Nifedipina Alter, clinicians should consider several safety factors.

  • Cardiovascular disease: assess for severe aortic stenosis or recent myocardial infarction.
  • Liver impairment: dose adjustment may be required in hepatic dysfunction.
  • Concomitant antihypertensives: monitor for additive blood‑pressure lowering effects.
  • Elderly patients: start with lower doses and monitor for orthostatic hypotension.
  • Pregnancy and lactation: use only if the potential benefit justifies the potential risk.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging, and protect from moisture.

Avoid Interactions

Nifedipine can interact with several medicines, altering its efficacy or safety.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin): may increase nifedipine plasma levels and risk toxicity.
  • Grapefruit juice: can markedly raise drug concentrations.
  • Concurrent use with other potent vasodilators: may cause severe hypotension.

Moderate Interactions (Monitor Closely):\n- Beta‑blockers: may mask tachycardia but enhance antihypertensive effect.

  • Diuretics: increased risk of electrolyte imbalance and hypotension.
  • Antacids containing aluminum or magnesium: may reduce oral absorption; separate dosing by at least 2 hours.

Frequently Asked Questions

Nifedipina Alter contains nifedipine, which is prescribed to treat hypertension, chronic stable angina, and Raynaud's phenomenon. By relaxing blood vessels, it helps lower blood pressure, reduces chest pain caused by reduced heart blood flow, and improves circulation in peripheral arteries affected by Raynaud's attacks.

Nifedipine blocks L‑type calcium channels on vascular smooth muscle and cardiac cells. This inhibition prevents calcium from entering the cells, leading to relaxation of arterial walls, vasodilation, and a decrease in peripheral resistance. The resulting effect lowers blood pressure and reduces the heart's workload, which alleviates angina and improves peripheral blood flow.

The specific dose of Nifedipina Alter is determined by the prescribing clinician based on the individual’s medical condition, response to therapy, and other factors. Healthcare professionals tailor the regimen to achieve optimal blood‑pressure control or angina relief while minimizing side effects.

Safety of nifedipine in pregnancy or while nursing has not been fully established. It should only be used if the potential therapeutic benefit justifies any possible risk to the fetus or infant. Physicians will evaluate the risk‑benefit profile before prescribing to pregnant or lactating patients.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Nifedipine belongs to the calcium‑channel blocker class, which differs from ACE inhibitors, ARBs, or beta‑blockers in its mechanism of causing direct vasodilation. Compared with other antihypertensives, it provides rapid blood‑pressure reduction and is especially useful when patients have concomitant angina or Raynaud's phenomenon. Choice of therapy depends on individual patient profiles and comorbidities.

Nifedipina Alter should be stored at ambient temperature, preferably below 25 °C. Keep the product in its original packaging, protect it from moisture, and store it out of direct sunlight. Do not refrigerate or freeze the tablets, as temperature extremes can affect stability.

Nifedipina Alter is taken orally, usually with a glass of water. The tablet should be swallowed whole and not crushed or chewed unless specifically instructed by a healthcare professional. Dosing frequency and timing are set by the prescriber based on the therapeutic goal and patient response.

Serious risks include severe hypotension, myocardial infarction, atrioventricular block, and rare cases of hepatotoxicity or severe allergic reactions. Patients should be monitored for signs of chest pain, fainting, rapid heartbeat, or skin rash, and seek immediate medical attention if any of these occur.

Nifedipina Alter is contraindicated in patients with known hypersensitivity to nifedipine or any other calcium‑channel blocker, those with severe aortic stenosis, and individuals who have experienced a serious reaction to the drug previously. Clinicians should also exercise caution in patients with significant liver impairment or unstable cardiac conditions.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.