Product image of Nifedipina Mylan Generics (Nifedipine) supplied by GNH India

Nifedipina Mylan Generics

Active Ingredient:
Nifedipine
Origin:
EU

Nifedipina Mylan Generics (Nifedipine)

Nifedipine, the active ingredient in Nifedipina Mylan Generics, is a calcium channel blocker presented as an oral formulation for oral use. It is employed to manage high blood pressure, relieve chest pain from angina, and improve blood flow in Raynaud's phenomenon.

GNH India supplies Nifedipina Mylan Generics as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, and ensures reliable logistics. The company adheres to stringent quality standards and provides regulatory documentation to support safe distribution across global markets.

Manufacturer / TM Owner

Mylan S.P.A.

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Indications & Clinical Uses

Nifedipine is a calcium channel blocker used to treat vascular and cardiac conditions.

  • Hypertension: reduces systemic vascular resistance, leading to sustained blood pressure control in adults with primary hypertension.
  • Angina pectoris: dilates coronary arteries and lowers myocardial oxygen demand, providing relief from exertional chest pain.
  • Raynaud's phenomenon: relaxes digital arterioles, enhancing peripheral blood flow and decreasing the frequency of vasospastic attacks.

How It Works

  • Nifedipine selectively blocks L-type calcium channels on vascular smooth muscle and myocardial cells, decreasing calcium influx. This inhibition causes arterial vasodilation, lowers peripheral resistance, and reduces myocardial oxygen consumption, thereby lowering blood pressure and alleviating ischemic chest pain.

Side Effects

Nifedipine may cause a range of adverse reactions.

Common Side Effects

  • Headache
  • Flushing
  • Peripheral edema
  • Dizziness

Serious or Rare Side Effects

  • Severe hypotension
  • Myocardial infarction
  • Allergic reactions such as rash or angioedema

Precautions & Warnings

Before initiating therapy, several precautions should be considered.

  • Monitor blood pressure: check regularly to avoid excessive hypotension.
  • Assess cardiac function: evaluate for existing heart failure or recent myocardial infarction.
  • Use caution in hepatic impairment: dose adjustments may be required.
  • Avoid abrupt discontinuation: tapering helps prevent rebound hypertension.
  • Review concomitant medications: consider additive effects with other antihypertensives.
  • Store at room temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Nifedipine can interact with several drug classes.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin) may raise plasma levels.
  • Co‑administration with other antihypertensives can cause excessive blood pressure drop.
  • Grapefruit juice may increase nifedipine exposure.

Moderate Interactions (Monitor Closely):\n- Beta‑blockers: may blunt compensatory heart rate response.

  • Diuretics: additive hypotensive effect.
  • Digoxin: increased risk of arrhythmia when combined with significant hypotension.

Frequently Asked Questions

Nifedipina Mylan Generics contains nifedipine, a calcium channel blocker indicated for the treatment of hypertension, angina pectoris, and Raynaud's phenomenon. It works by relaxing blood vessels, which helps lower blood pressure and improve blood flow to the heart and peripheral tissues.

Nifedipine blocks L-type calcium channels on vascular smooth‑muscle cells and cardiac myocytes. By reducing calcium entry, it causes arterial vasodilation, lowers peripheral resistance, and decreases myocardial oxygen demand, which together lower blood pressure and relieve chest pain.

The appropriate dose is determined by the prescribing healthcare professional based on the individual’s condition, response, and other medications. Patients should follow the prescriber’s instructions and not adjust the dose without medical guidance.

Safety data for nifedipine in pregnancy and lactation are limited. It should only be used if the potential benefit outweighs the risk, and the decision must be made by a qualified healthcare provider after careful evaluation.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Nifedipine belongs to the dihydropyridine calcium‑channel blocker class, which primarily causes arterial vasodilation. Compared with beta‑blockers, it has less effect on heart rate, and unlike ACE inhibitors, it does not interfere with the renin‑angiotensin system. Choice depends on patient profile and comorbidities.

Store the product at room temperature, below 25 °C, in the original container. Protect it from moisture and direct sunlight. Do not use if the packaging is damaged or the tablets appear discolored.

The medication is taken orally. Swallow the tablet whole with a full glass of water, preferably at the same time each day. Do not crush, chew, or split extended‑release formulations unless instructed by a pharmacist.

Serious adverse events include severe hypotension, myocardial infarction, and allergic reactions such as rash, angioedema, or anaphylaxis. Patients should seek immediate medical attention if they experience sudden dizziness, fainting, chest pain, or signs of an allergic response.

Individuals with known hypersensitivity to nifedipine or any component of the formulation, those experiencing severe hypotension, cardiogenic shock, or recent myocardial infarction should avoid this medication. A healthcare professional must evaluate any contraindications before prescribing.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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