Product image of Nifedipine Retard Teva (Nifedipine) supplied by GNH India

Nifedipine Retard Teva

Active Ingredient:
Nifedipine
Origin:
EU

Nifedipine Retard Teva (Nifedipine)

Nifedipine, the active ingredient in Nifedipine Retard Teva, is a calcium channel blocker presented as an oral tablet for oral use. It treats hypertension and angina pectoris by relaxing vascular smooth muscle and reducing cardiac workload.

GNH India supplies Nifedipine Retard Teva as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva Nederland B.V.

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Indications & Clinical Uses

  • Nifedipine is a calcium channel blocker used to manage conditions related to vascular tone and cardiac workload.
  • Hypertension: lowers elevated blood pressure and reduces risk of cardiovascular complications.
  • Angina pectoris: relieves chest pain by improving myocardial oxygen supply.
  • Chronic stable angina: decreases frequency of angina attacks and improves exercise tolerance.

How It Works

  • Nifedipine selectively blocks L‑type calcium channels in vascular smooth muscle and myocardial cells, inhibiting calcium influx. This causes arterial vasodilation, reduces peripheral resistance, and lowers myocardial oxygen demand, leading to decreased blood pressure and relief of anginal symptoms.

Side Effects

Nifedipine may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Headache
  • Flushing
  • Peripheral edema
  • Dizziness

Serious or Rare Side Effects

  • Severe hypotension
  • Myocardial infarction
  • Severe allergic reaction (e.g., anaphylaxis)

Precautions & Warnings

  • Before initiating therapy, consider the following safety measures.
  • Monitor blood pressure regularly: ensure therapeutic effect without excessive hypotension.
  • Assess hepatic function: dose adjustment may be needed in liver impairment.
  • Avoid abrupt discontinuation: taper to prevent rebound hypertension.
  • Use caution in heart failure: monitor for worsening symptoms.
  • Review concomitant medications: evaluate for additive hypotensive effects.
  • Store at room temperature: keep in the original container, protect from moisture.

Avoid Interactions

Nifedipine can interact with several drug classes; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): increase nifedipine levels.
  • Grapefruit juice: markedly raises plasma concentration.
  • Other antihypertensives (e.g., beta‑blockers, ACE inhibitors): additive hypotensive effect.
  • Certain antiarrhythmics (e.g., quinidine): risk of arrhythmias.
  • Simultaneous use with other calcium channel blockers: may cause excessive vasodilation.

Moderate Interactions (Monitor Closely)

  • Diuretics: may enhance blood pressure lowering.
  • Digoxin: increased risk of digoxin toxicity.
  • Statins metabolized by CYP3A4 (e.g., atorvastatin): monitor for muscle toxicity.

Frequently Asked Questions

Nifedipine Retard Teva is prescribed to lower high blood pressure (hypertension) and to relieve chest pain caused by angina pectoris. By relaxing blood vessels, it improves blood flow and reduces the heart's workload, helping prevent cardiovascular complications.

Nifedipine blocks L‑type calcium channels in the smooth muscle of arteries and in cardiac muscle. This inhibition prevents calcium entry, leading to vasodilation, reduced peripheral resistance, and lower myocardial oxygen demand, which together control blood pressure and alleviate angina.

The specific dose and dosing schedule are determined by the prescribing clinician based on the patient’s condition, response, and other medical factors. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety in pregnancy and lactation has not been definitively established. The drug should only be used if the potential benefit justifies the possible risk to the fetus or infant, and this decision must be made by a qualified healthcare professional.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Nifedipine belongs to the calcium channel blocker class, which primarily causes arterial vasodilation. Compared with ACE inhibitors or beta‑blockers, it may have a quicker onset of blood‑pressure reduction but can be associated with peripheral edema. Choice of therapy depends on individual patient profile and comorbidities.

Store the tablets at room temperature, below 25 °C, in the original packaging. Protect them from moisture and direct sunlight to maintain stability. Do not refrigerate or freeze the product.

The medication is taken orally, usually with a full glass of water. It may be prescribed as a once‑daily or twice‑daily regimen, depending on the formulation and the prescriber’s recommendation. Swallow the tablet whole; do not crush or chew unless instructed otherwise.

Serious risks include severe hypotension, myocardial infarction, and life‑threatening allergic reactions such as anaphylaxis. Patients should seek immediate medical attention if they experience sudden dizziness, fainting, chest pain, or signs of an allergic response.

Individuals with known hypersensitivity to nifedipine or any component of the formulation should avoid the drug. Caution is also advised for patients with severe aortic stenosis, uncontrolled heart failure, or those taking contraindicated medications such as strong CYP3A4 inhibitors.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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