Product image of Nifedipine Teva (Nifedipine) supplied by GNH India

Nifedipine Teva

Active Ingredient:
Nifedipine
Origin:
EU

Nifedipine Teva (Nifedipine)

Nifedipine, the active ingredient in Nifedipine Teva, is a calcium channel blocker presented as a tablet for oral use. It treats hypertension and angina pectoris in adults.
GNH India supplies Nifedipine Teva as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Teva Nederland B.V.

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Indications & Clinical Uses

  • Nifedipine is a dihydropyridine calcium channel blocker used to manage cardiovascular conditions.
  • Hypertension: lowers blood pressure by relaxing arterial smooth muscle.
  • Angina pectoris: reduces myocardial oxygen demand by decreasing afterload.
  • Coronary artery spasm: alleviates vasospasm and improves coronary blood flow.

How It Works

  • Nifedipine selectively blocks L-type calcium channels in vascular smooth muscle, preventing calcium influx that is necessary for contraction. This inhibition leads to vasodilation of peripheral arteries, reduced systemic vascular resistance, and consequently lower blood pressure and myocardial workload.

Side Effects

Nifedipine may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Flushing: warm sensation, often on the face and neck.
  • Peripheral edema: swelling of ankles or feet.
  • Dizziness or light‑headedness.
  • Nausea: occasional gastrointestinal upset.
  • Tachycardia: increased heart rate.

Serious or Rare Side Effects

  • Severe hypotension: marked drop in blood pressure.
  • Myocardial infarction: rare but possible cardiac event.
  • Arrhythmias: abnormal heart rhythms.
  • Hepatic dysfunction: elevated liver enzymes.
  • Allergic reactions: rash, pruritus, or anaphylaxis.
  • Stevens‑Johnson syndrome: severe skin reaction.

Precautions & Warnings

  • Before initiating therapy, clinicians should evaluate patient‑specific factors and monitor for potential complications.
  • Monitor blood pressure: ensure adequate control without excessive drop.
  • Assess cardiac function: especially in patients with existing heart disease.
  • Avoid abrupt discontinuation: taper to prevent rebound hypertension.
  • Use caution in hepatic impairment: metabolism may be reduced.
  • Use caution in elderly patients: increased sensitivity to hypotension.
  • Store at room temperature: keep in the original pack, protect from moisture.

Avoid Interactions

Nifedipine can interact with several medicines, altering its effectiveness or safety profile.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole): increase plasma levels.
  • Concurrent use with other potent vasodilators (e.g., nitroglycerin): risk of severe hypotension.
  • Grapefruit juice: can raise nifedipine concentrations.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: may enhance bradycardia or hypotension.
  • Diuretics: may increase risk of electrolyte imbalance and low blood pressure.

Frequently Asked Questions

Nifedipine Teva is prescribed to manage high blood pressure (hypertension) and to relieve chest pain caused by reduced blood flow to the heart (angina pectoris). It works by relaxing the smooth muscle in blood vessels, which lowers vascular resistance and improves cardiac oxygen supply.

Nifedipine blocks L‑type calcium channels on vascular smooth‑muscle cells, preventing calcium entry that is required for muscle contraction. This results in vasodilation of peripheral arteries, decreased systemic vascular resistance, and reduced workload on the heart, helping to control blood pressure and alleviate angina.

The appropriate dose of Nifedipine Teva is determined by the prescribing healthcare professional based on the patient’s medical condition, response to therapy, and other individual factors. Dosage adjustments are made according to clinical judgment and monitoring.

Safety data for Nifedipine Teva in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Nifedipine belongs to the dihydropyridine calcium‑channel blocker class, which primarily causes arterial vasodilation. Compared with beta‑blockers or ACE inhibitors, it has a rapid onset of vasodilatory effect and may be preferred when a strong peripheral arterial relaxation is needed, but individual therapy should be tailored to the patient’s overall profile.

Nifedipine Teva should be stored at room temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and avoid storing it in humid environments such as bathrooms.

Nifedipine Teva is taken orally, usually with a glass of water. The tablet should be swallowed whole and not chewed or crushed unless specifically instructed by a healthcare professional. Dosing times and frequency are set by the prescriber.

Serious risks include severe hypotension, myocardial infarction, life‑threatening arrhythmias, and rare severe skin reactions such as Stevens‑Johnson syndrome. Patients should be monitored for sudden drops in blood pressure, chest pain, or any signs of allergic reaction, and seek immediate medical attention if they occur.

Nifedipine Teva is contraindicated in patients with known hypersensitivity to nifedipine or any component of the formulation, and in those with severe aortic stenosis or cardiogenic shock. Caution is also advised for individuals with significant liver disease, uncontrolled heart failure, or those taking interacting medications listed under major interactions.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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