Product image of Niferex (Ferrous (Ii) Glycine Sulfate Complex) supplied by GNH India

Niferex

Active Ingredient:
Ferrous (Ii) Glycine Sulfate Complex
Origin:
EU

Niferex (Ferrous (Ii) Glycine Sulfate Complex)

Ferrous (II) Glycine Sulfate Complex, the active ingredient in Niferex, is an iron supplement presented as an oral formulation for oral use. It is used to prevent and treat iron deficiency and iron‑deficiency anemia in individuals who require additional dietary iron.

GNH India supplies Niferex as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Ucb Pharma Gmbh

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Indications & Clinical Uses

Niferex is an oral iron supplement that addresses conditions related to insufficient iron availability.

  • Iron deficiency anemia: helps restore normal hemoglobin and red blood cell counts.
  • Prevention of iron deficiency: supports maintenance of adequate iron stores in at‑risk populations.
  • Anemia due to chronic blood loss: provides supplemental iron to compensate for ongoing losses.

How It Works

  • Ferrous (II) Glycine Sulfate Complex dissociates in the gastrointestinal tract, releasing ferrous iron that is readily absorbed via the divalent metal transporter‑1 (DMT‑1) in the duodenum. The absorbed iron enters the plasma, binds to transferrin, and is delivered to the bone marrow for incorporation into hemoglobin and to other tissues for iron‑dependent enzymatic processes.

Side Effects

Iron supplementation can be associated with a range of adverse reactions.

Common Side Effects

  • Nausea: mild to moderate stomach discomfort.
  • Constipation: reduced bowel movements.
  • Diarrhea: loose stools in some individuals.
  • Dark stools: harmless change in stool color.
  • Metallic taste: transient after ingestion.

Serious or Rare Side Effects

  • Severe allergic reaction: rash, itching, swelling, or difficulty breathing.
  • Iron overload: symptoms of organ dysfunction in cases of excessive dosing.
  • Gastrointestinal bleeding: uncommon but serious.
  • Hypotension: rare, especially with rapid intravenous administration (not applicable to oral form).

Precautions & Warnings

When using Niferex, consider the following safety measures.

  • Assess iron status: confirm deficiency before initiating therapy.
  • Monitor hemoglobin: periodic testing to avoid excess iron.
  • Pregnancy and lactation: use only if prescribed after risk‑benefit evaluation.
  • Drug interactions: separate dosing from antacids or calcium supplements.
  • Storage: Store below 25°C: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

Iron supplements can affect the absorption or efficacy of other medications.

Major Interactions (Avoid)

  • Tetracycline antibiotics: chelation reduces antibiotic absorption.
  • Fluoroquinolones (e.g., ciprofloxacin): decreased antimicrobial effectiveness.
  • Levothyroxine: impaired thyroid hormone uptake.

Moderate Interactions (Monitor Closely)

  • Antacids containing aluminum or magnesium: may lower iron absorption.
  • Calcium supplements or dairy products: compete for intestinal uptake.
  • Proton pump inhibitors: may reduce gastric acidity and iron solubility.

Frequently Asked Questions

Niferex is an oral iron supplement indicated for the prevention of iron deficiency and the treatment of iron‑deficiency anemia. It helps restore normal hemoglobin levels and supports adequate iron stores in individuals with low iron status.

The complex releases ferrous iron in the gastrointestinal tract, which is absorbed through the duodenal divalent metal transporter‑1. The absorbed iron binds to transferrin, delivering it to the bone marrow for hemoglobin synthesis and to other tissues for essential enzymatic functions.

The appropriate dose of Niferex is determined by a qualified healthcare professional based on the patient’s iron status, age, weight, and clinical condition. Prescribers tailor the regimen to achieve optimal therapeutic outcomes while minimizing the risk of excess iron.

Use of Niferex during pregnancy or lactation should be guided by a prescriber. Iron supplementation may be necessary in these periods, but the decision must weigh potential benefits against any risks, following current clinical guidelines.

To order Niferex, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and necessary import documentation.

Niferex delivers iron as a ferrous glycine sulfate complex, which is designed for high bioavailability. Compared with ferrous sulfate tablets, the glycine chelate may improve absorption and reduce gastrointestinal irritation, though individual response can vary.

Store Niferex below 25 °C in its original packaging, protecting it from moisture and direct sunlight. Keep the product out of reach of children and avoid storing in humid environments such as bathrooms.

Niferex is taken orally, usually with water. It is recommended to ingest the tablet on an empty stomach for optimal absorption, but if gastrointestinal upset occurs, it may be taken with a small amount of food. Follow the prescriber’s instructions regarding timing and dosage.

Serious risks include severe allergic reactions (rash, swelling, breathing difficulty) and iron overload, which can cause organ damage. Patients should report any signs of hypersensitivity or unusual symptoms promptly to a healthcare professional.

Niferex should be avoided in individuals with known hypersensitivity to ferrous compounds, those with hemochromatosis or other iron‑storage disorders, and patients who have experienced severe reactions to oral iron preparations. Consultation with a prescriber is essential before initiating therapy.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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