Product image of Nilox Mini (Nitroxoline) supplied by GNH India

Nilox Mini

Active Ingredient:
Nitroxoline
Origin:
EU

Nilox Mini (Nitroxoline)

Nitroxoline, the active ingredient in Nilox Mini, is an antibacterial presented as an oral dosage form for oral use. It is indicated for the treatment of urinary tract infections in adults and children where appropriate.
GNH India supplies Nilox Mini as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Cnp Pharma Gmbh

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Nitroxoline is used to manage infections of the urinary tract by targeting bacterial growth.

  • Uncomplicated urinary tract infection: reduces bacterial load and alleviates symptoms.
  • Acute cystitis: helps eradicate the causative organisms and shortens disease duration.
  • Pyelonephritis: contributes to bacterial clearance in upper urinary tract infection.

How It Works

  • Nitroxoline exerts antibacterial activity by inhibiting bacterial enzymes involved in nucleic acid synthesis and interfering with DNA replication. This dual action disrupts essential metabolic pathways in both Gram‑negative and Gram‑positive organisms, particularly those colonising the urinary tract, leading to bacterial death or growth inhibition.

Side Effects

Nitroxoline may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Nausea: mild to moderate upset stomach.
  • Vomiting: occasional episodes after dosing.
  • Abdominal pain: cramp‑like discomfort.
  • Headache: transient mild headache.
  • Dyspepsia: indigestion or heartburn.
  • Rash: mild skin erythema.

Serious or Rare Side Effects

  • Anaphylaxis: severe allergic reaction requiring immediate medical attention.
  • Hepatic enzyme elevation: signs of liver irritation or injury.
  • Blood dyscrasias: rare cases of neutropenia or thrombocytopenia.
  • Stevens‑Johnson syndrome: severe skin and mucous membrane disorder.

Precautions & Warnings

Before prescribing Nilox Mini, clinicians should consider several safety aspects.

  • Renal impairment: monitor renal function and adjust therapy if needed.
  • Hepatic dysfunction: use with caution and observe liver enzymes.
  • Pregnancy: safety category unknown; avoid unless benefits outweigh risks.
  • Breastfeeding: unknown excretion in milk; consider alternative therapy.
  • Elderly patients: increased susceptibility to adverse effects; monitor closely.
  • Store at ambient temperature: keep in the original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Nitroxoline can interact with other medicines, requiring attention to avoid reduced efficacy or increased toxicity.

Major Interactions (Avoid)

  • Metal cations (iron, calcium, magnesium supplements): may markedly decrease nitroxoline absorption.
  • Anticoagulants (warfarin): potential enhancement of bleeding risk.

Moderate Interactions (Monitor Closely)

  • NSAIDs: may increase risk of renal toxicity when combined.
  • Diuretics: possible electrolyte disturbances.
  • Other antibiotics (e.g., quinolones): additive antimicrobial toxicity may occur.

Frequently Asked Questions

Nilox Mini contains nitroxoline and is prescribed to treat urinary tract infections. It targets the bacteria that cause conditions such as acute cystitis and uncomplicated lower urinary tract infections, helping to clear the infection and relieve associated symptoms.

Nitroxoline inhibits bacterial enzymes that are essential for DNA synthesis and interferes with nucleic acid replication. By disrupting these processes, it prevents bacterial growth and promotes bacterial death, particularly against organisms commonly found in the urinary tract.

The dosage of Nilox Mini is determined by the prescribing clinician based on the patient’s age, weight, renal function and severity of infection. Healthcare professionals tailor the regimen to achieve optimal therapeutic effect while minimizing risk.

The safety of nitroxoline during pregnancy and lactation has not been established. It should be used only if the potential benefit justifies the potential risk to the fetus or infant, and alternative agents with known safety profiles are preferred.

To order Nilox Mini, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

The most common alternative for urinary tract infections is trimethoprim‑sulfamethoxazole. Nitroxoline offers a different mechanism of action, which can be advantageous in cases of resistance to sulfonamides. Both agents are prescription‑only, but nitroxoline may have a distinct side‑effect profile and drug‑interaction considerations.

Nilox Mini should be stored at ambient temperature, below 25 °C, in its original container to protect it from moisture and light. Keep the product out of reach of children and avoid storing in bathrooms or other humid environments.

Nilox Mini is administered orally, usually with a glass of water. The tablet should be swallowed whole unless the prescriber advises otherwise. It is taken according to the schedule set by the healthcare professional, which may involve dosing with or without food.

Serious adverse reactions, although rare, include severe allergic responses such as anaphylaxis, significant liver enzyme elevations indicating hepatic injury, blood dyscrasias like neutropenia, and severe skin reactions such as Stevens‑Johnson syndrome. Patients should seek immediate medical attention if they experience any of these symptoms.

Nilox Mini should be avoided in individuals with known hypersensitivity to nitroxoline or any component of the formulation. Caution is also advised for patients with severe renal or hepatic impairment, and it is generally not recommended for pregnant or breastfeeding women unless clearly indicated by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.