Product image of Nimodipin Hexal (Nimodipine) supplied by GNH India

Nimodipin Hexal

Active Ingredient:
Nimodipine
Origin:
EU

Nimodipin Hexal (Nimodipine)

Nimodipine, the active ingredient in Nimodipin Hexal, is a calcium channel blocker presented as an oral tablet for oral use. It helps prevent cerebral vasospasm following subarachnoid hemorrhage in adult patients.

GNH India supplies Nimodipin Hexal as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Hexal Ag

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Nimodipine is used to address vascular complications within the cerebral circulation, particularly after subarachnoid hemorrhage.

  • Prevention of cerebral vasospasm after subarachnoid hemorrhage: reduces the risk of delayed ischemic neurological deficits.
  • Management of delayed cerebral ischemia: lowers the incidence of secondary brain injury.
  • Support of neurological recovery after aneurysmal subarachnoid hemorrhage: contributes to improved functional outcomes.

How It Works

  • Nimodipine selectively blocks L‑type calcium channels in vascular smooth muscle, especially in cerebral arteries. By inhibiting calcium influx, it induces vasodilation, decreases arterial tone, and mitigates the development of vasospasm that can follow subarachnoid hemorrhage, thereby preserving cerebral blood flow.

Side Effects

Nimodipine may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Dizziness or light‑headedness: often positional.
  • Nausea or gastrointestinal discomfort.
  • Flushing: transient warmth of the skin.
  • Hypotension: mild blood pressure reduction.
  • Peripheral edema: mild swelling of the lower limbs.

Serious or Rare Side Effects

  • Severe hypotension: marked drop in blood pressure requiring medical attention.
  • Bradycardia: unusually slow heart rate.
  • Hepatic dysfunction: abnormal liver enzyme levels.
  • Allergic reactions: rash, pruritus, or angioedema.
  • Cardiac arrhythmias: irregular heart rhythms.
  • Hemorrhagic complications: rare bleeding events.

Precautions & Warnings

Before initiating therapy, clinicians should evaluate patient‑specific factors and monitor for potential complications.

  • Renal impairment: adjust monitoring as clearance may be reduced.
  • Hepatic dysfunction: consider baseline liver function tests.
  • Concomitant antihypertensives: watch for additive blood pressure lowering.
  • Pregnancy and lactation: use only if clearly needed after risk‑benefit assessment.
  • Elderly patients: start at lower doses and titrate cautiously.
  • Store at ambient temperature: keep below 25 °C, retain in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Nimodipine can interact with several drug classes, altering its efficacy or safety profile.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin): may increase plasma concentrations and risk of toxicity.
  • Concurrent use with other potent vasodilators: can cause severe hypotension.
  • Nitrates: additive vasodilatory effect leading to dangerous blood pressure drops.

Moderate Interactions (Monitor Closely):\n- CYP3A4 inducers (e.g., rifampicin, carbamazepine): may reduce therapeutic levels.

  • Beta‑blockers: may mask tachycardia signs of hypotension.
  • Diuretics: enhanced risk of electrolyte disturbances and low blood pressure.

Frequently Asked Questions

Nimodipin Hexal contains the active ingredient nimodipine, which is prescribed to prevent cerebral vasospasm following a subarachnoid hemorrhage. By maintaining adequate blood flow in the brain’s vessels, it helps reduce the risk of delayed ischemic neurological deficits in adult patients.

Nimodipine selectively blocks L‑type calcium channels on vascular smooth muscle, especially within cerebral arteries. This inhibition reduces calcium entry into the cells, causing vasodilation and preventing the narrowing (vasospasm) that can occur after a subarachnoid hemorrhage, thereby supporting cerebral perfusion.

The specific dose and dosing schedule of Nimodipin Hexal are determined by the prescribing physician based on the patient’s clinical condition, weight, and response to therapy. Healthcare professionals tailor the regimen to achieve optimal prevention of vasospasm while minimizing adverse effects.

Safety data for nimodipine in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare provider after a thorough risk‑benefit assessment.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements), and necessary import documentation.

Nimodipine is a dihydropyridine calcium channel blocker with a high affinity for cerebral vessels, making it particularly effective for preventing vasospasm after subarachnoid hemorrhage. Other vasodilators, such as nitroglycerin or other calcium channel blockers, may have broader systemic effects and are not as specifically targeted to the brain’s vasculature.

Nimodipin Hexal should be stored at ambient temperature, preferably below 25 °C. Keep the tablets in their original packaging, protect them from moisture, heat, and direct sunlight to maintain product stability throughout its shelf life.

The medication is taken orally, usually in tablet form, as directed by the prescribing clinician. It is commonly administered with or without food, depending on the physician’s instructions, and patients should follow the exact schedule provided to ensure consistent plasma levels.

Serious adverse events, though rare, include severe hypotension, bradycardia, significant hepatic dysfunction, and allergic reactions such as rash or angioedema. Patients should be monitored for these signs, and any sudden changes in blood pressure or heart rate warrant immediate medical attention.

Nimodipin Hexal is contraindicated in patients with known hypersensitivity to nimodipine or any component of the formulation. It should also be avoided in individuals taking strong CYP3A4 inhibitors or other potent vasodilators without close medical supervision, as these combinations can lead to dangerous drops in blood pressure.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.