Product image of Nimodipina Pensa (Nimodipine) supplied by GNH India

Nimodipina Pensa

Active Ingredient:
Nimodipine
Origin:
EU

Nimodipina Pensa (Nimodipine)

Nimodipine, the active ingredient in Nimodipina Pensa, is a calcium channel blocker (dihydropyridine) presented as an oral formulation for oral use. It is employed to prevent cerebral vasospasm following subarachnoid hemorrhage in adult patients.
GNH India supplies Nimodipina Pensa as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Towa Pharmaceutical S.P.A.

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Indications & Clinical Uses

Nimodipine acts on cerebral vascular smooth muscle to reduce vasospasm after hemorrhagic events.

  • Subarachnoid hemorrhage: prevention of cerebral vasospasm after aneurysmal bleed
  • Cerebral vasospasm: reduction of vessel constriction to improve cerebral blood flow
  • Neurological complications post‑SAH: support of recovery by maintaining adequate perfusion

How It Works

  • Nimodipine selectively blocks voltage‑dependent L‑type calcium channels in cerebral arterial smooth muscle. This inhibition reduces calcium influx, causing vasodilation of intracranial vessels, which increases cerebral blood flow and mitigates the risk of ischemic injury after subarachnoid hemorrhage.

Side Effects

Nimodipine may cause a range of adverse reactions, most of which are dose‑related and reversible.

Common Side Effects

  • Headache: mild to moderate intensity
  • Hypotension: transient blood pressure drop
  • Nausea: occasional gastrointestinal upset
  • Flushing: warmth and redness of skin
  • Dizziness: sensation of light‑headedness
  • Tachycardia: increased heart rate

Serious or Rare Side Effects

  • Severe hypotension: marked blood pressure reduction requiring medical attention
  • Myocardial infarction: rare cardiac ischemic events
  • Hepatic dysfunction: abnormal liver enzymes or hepatitis
  • Allergic reactions: rash, pruritus, or anaphylaxis
  • Blood dyscrasias: neutropenia or thrombocytopenia

Precautions & Warnings

Before prescribing Nimodipina Pensa, clinicians should consider several safety aspects.

  • Blood pressure monitoring: check for hypotension, especially after initiation
  • Hepatic impairment: adjust use in patients with severe liver disease
  • Pregnancy: category C, use only if benefit outweighs risk
  • Elderly patients: start at lower dose and monitor closely
  • Concomitant antihypertensives: avoid excessive blood pressure lowering
  • Store below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Nimodipine can interact with other medicines, altering its efficacy or safety.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin): increase nimodipine levels
  • Potent vasodilators (e.g., nitroglycerin): risk of severe hypotension
  • Other calcium‑channel blockers: additive cardiovascular effects

Moderate Interactions (Monitor Closely):\n- Antihypertensive agents (beta‑blockers, ACE inhibitors): monitor blood pressure

  • CYP3A4 substrates (e.g., statins): possible increased exposure
  • Diuretics: watch for electrolyte disturbances
  • NSAIDs: may blunt antihypertensive effect

Frequently Asked Questions

Nimodipina Pensa contains nimodipine, which is prescribed to prevent cerebral vasospasm after an aneurysmal subarachnoid hemorrhage. By keeping the brain’s blood vessels dilated, it helps maintain adequate cerebral blood flow during the critical recovery period.

Nimodipine selectively blocks L‑type calcium channels in the smooth muscle of cerebral arteries. This reduces calcium entry, causing the vessels to relax and dilate, which increases blood flow to the brain and reduces the risk of ischemic injury after hemorrhage.

The specific dose and dosing schedule are determined by the treating physician based on the patient’s clinical condition, weight, and response. Nimodipina Pensa is a prescription‑only product, and dosing should follow the prescriber’s instructions.

Nimodipine is classified as pregnancy category C, meaning risk cannot be ruled out. It should only be used if the potential benefit justifies the potential risk to the fetus. Breastfeeding is not recommended unless the benefit to the mother outweighs possible effects on the infant.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Nimodipine is a dihydropyridine calcium‑channel blocker with high selectivity for cerebral vessels, offering a favorable balance of efficacy and tolerability for preventing vasospasm after subarachnoid hemorrhage. Other vasodilators may lack this cerebral selectivity or have a different side‑effect profile, making nimodipine the preferred choice in most guidelines.

Store Nimodipina Pensa below 25 °C in its original packaging. Protect the product from moisture and direct sunlight to maintain stability throughout its shelf life.

Nimodipina Pensa is taken orally, usually as a tablet, with or without food as directed by the prescriber. The exact administration schedule should follow the healthcare professional’s guidance.

Serious risks include severe hypotension, myocardial infarction, hepatic dysfunction, allergic reactions such as anaphylaxis, and rare blood disorders like neutropenia. Patients should be monitored for these events, especially during treatment initiation.

Nimodipina Pensa is contraindicated in patients with known hypersensitivity to nimodipine or any excipients, and in those with severe hypotension or uncontrolled heart failure. Caution is also advised for individuals with significant liver impairment.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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