Product image of Nimotop (Nimodipine) supplied by GNH India

Nimotop

Active Ingredient:
Nimodipine
Origin:
EU

Nimotop (Nimodipine)

Nimodipine, the active ingredient in Nimotop, is a calcium channel blocker (dihydropyridine) presented as a tablet for oral use. It is used to prevent cerebral vasospasm following subarachnoid hemorrhage in adult patients.

GNH India supplies Nimotop as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Bayer Portugal Lda

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Nimotop is a calcium channel blocker used in the management of cerebral vasospasm after subarachnoid hemorrhage.
  • Cerebral vasospasm after subarachnoid hemorrhage: reduces the risk of delayed ischemic neurological deficits.

How It Works

  • Nimodipine selectively blocks L‑type calcium channels on vascular smooth‑muscle cells, especially within cerebral arteries. This inhibition decreases calcium influx, leading to vasodilation of intracranial vessels and improved cerebral blood flow, thereby mitigating the development of vasospasm after subarachnoid hemorrhage.

Side Effects

Nimotop may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Dizziness or light‑headedness.
  • Flushing or warmth sensation.
  • Nausea or vomiting.
  • Low blood pressure (hypotension).
  • Peripheral edema.

Serious or Rare Side Effects

  • Severe hypotension or shock.
  • Bradycardia or heart block.
  • Allergic reactions including rash, pruritus, or anaphylaxis.
  • Hepatic enzyme elevation or liver injury.
  • Hematologic abnormalities such as neutropenia.
  • Myocardial infarction or cardiac ischemia.

Precautions & Warnings

  • Before initiating therapy, clinicians should consider several safety measures.
  • Monitor blood pressure: watch for symptomatic hypotension.
  • Assess hepatic function: use cautiously in patients with liver impairment.
  • Avoid abrupt discontinuation: taper if long‑term therapy is required.
  • Review concomitant antihypertensives: adjust doses to prevent additive effects.
  • Pregnancy and lactation: evaluate risk‑benefit ratio before prescribing.
  • Store at below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Nimotop can interact with several drug classes, requiring careful management.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., clarithromycin, itraconazole): may increase plasma levels.
  • Concurrent use with other calcium‑channel blockers: risk of excessive vasodilation.
  • Nitrates or other potent vasodilators: additive hypotensive effect.
  • Grapefruit juice: can raise nimodipine concentrations.

Moderate Interactions (Monitor Closely)

  • CYP3A4 inducers (e.g., rifampicin, carbamazepine): may reduce efficacy.
  • Diuretics: may potentiate blood‑pressure lowering.
  • Antacids containing aluminum or magnesium: could affect absorption.
  • Beta‑blockers: monitor for bradycardia.
  • Anticoagulants: observe for bleeding if hypotension occurs.

Frequently Asked Questions

Nimotop contains the active ingredient nimodipine and is indicated for the prophylaxis of cerebral vasospasm that can occur after a subarachnoid hemorrhage. By preventing vessel narrowing, it helps reduce the risk of delayed ischemic neurological deficits in affected patients.

Nimodipine blocks L‑type calcium channels in the smooth muscle of cerebral arteries. This action limits calcium entry into the cells, causing selective vasodilation of intracranial vessels, improving blood flow and decreasing the likelihood of vasospasm following hemorrhage.

The dose of Nimotop is determined by the prescribing physician based on clinical guidelines and the individual patient's condition. Typical regimens involve oral administration for a defined period after subarachnoid hemorrhage, but exact dosing must be individualized and confirmed by a healthcare professional.

Safety data for nimodipine in pregnancy and lactation are limited. It is generally avoided unless the potential benefit outweighs the possible risk to the fetus or infant. Women who are pregnant, planning pregnancy, or breastfeeding should discuss alternatives with their healthcare provider.

To place an order, submit an enquiry on the Nimotop product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Nimodipine is more selective for cerebral vessels than many other dihydropyridine calcium‑channel blockers such as nicardipine or amlodipine, which act more broadly on systemic vasculature. This selectivity makes nimodipine particularly effective for preventing vasospasm after subarachnoid hemorrhage while minimizing systemic blood‑pressure effects.

Nimotop tablets should be stored at temperatures below 25 °C, in their original packaging, and protected from moisture and direct sunlight. Do not store in bathrooms or near heat sources. Keep out of reach of children and dispose of any expired product according to local regulations.

Nimotop is supplied as oral tablets. The tablet should be swallowed whole with a glass of water, with or without food, as directed by the prescriber. Patients should follow the exact schedule provided by their healthcare professional to maintain consistent drug levels.

The most serious adverse events include severe hypotension, bradycardia, allergic reactions such as anaphylaxis, significant liver enzyme elevations, and rare hematologic abnormalities like neutropenia. Patients should seek immediate medical attention if they experience faintness, rapid heartbeat, rash, or signs of liver dysfunction.

Nimotop is contraindicated in individuals with known hypersensitivity to nimodipine or any excipients, patients with severe hypotension, and those with certain cardiac conduction disorders. Caution is also advised for patients with significant hepatic impairment or those taking interacting medications that could cause dangerous blood‑pressure drops.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.