Product image of Nimotop (Nimodipine) supplied by GNH India

Nimotop

Active Ingredient:
Nimodipine
Origin:
EU

Nimotop (Nimodipine)

Nimodipine, the active ingredient in Nimotop, is a calcium channel blocker presented as an oral tablet for oral use. It is used to prevent cerebral vasospasm following subarachnoid hemorrhage in patients at risk of ischemic complications.

GNH India supplies Nimotop as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratoire Xo

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Nimotop is a calcium channel blocker indicated for the management of cerebrovascular complications after subarachnoid hemorrhage.

  • Subarachnoid hemorrhage (post‑SAH): Prevention of cerebral vasospasm and associated ischemic injury.

How It Works

  • Nimodipine antagonizes L‑type calcium channels, with a preferential effect on cerebral arterial smooth muscle. By reducing calcium influx, it causes selective vasodilation of cerebral vessels, improving blood flow and limiting ischemic damage after subarachnoid hemorrhage.

Side Effects

Nimotop may cause a range of adverse reactions, most of which are mild and reversible.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Hypotension: transient blood‑pressure reduction.
  • Nausea: occasional gastrointestinal upset.
  • Flushing: warm sensation and reddening of skin.
  • Dizziness: sensation of light‑headedness.
  • Fatigue: general feeling of tiredness.

Serious or Rare Side Effects

  • Severe hypotension: marked drop in blood pressure requiring medical attention.
  • Bradycardia: unusually slow heart rate.
  • Hepatic dysfunction: abnormal liver enzyme elevations.
  • Allergic reaction: rash, itching, or swelling.
  • Neutropenia: reduced white‑blood‑cell count.
  • Seizures: rare occurrence of convulsive episodes.

Precautions & Warnings

Before initiating Nimotop, clinicians should evaluate patient‑specific risk factors and monitor for potential complications.

  • Blood pressure monitoring: check for hypotension during therapy.
  • Hepatic impairment: use with caution in patients with liver disease.
  • Concomitant vasodilators: avoid additive hypotensive effects.
  • Pregnancy: prescribe only if potential benefit outweighs risk.
  • Elderly patients: start at lower dose and titrate cautiously.
  • Store at below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Nimotop can interact with several drug classes, influencing its safety and efficacy.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole): may increase nimodipine plasma levels.
  • Other calcium channel blockers: additive vasodilatory effect leading to hypotension.
  • Nitrates: risk of severe hypotension.

Moderate Interactions (Monitor Closely)

  • CYP3A4 inducers (e.g., rifampin): may reduce therapeutic effect.
  • Beta‑blockers: combined effect on heart rate and blood pressure.
  • Diuretics: may enhance orthostatic hypotension.

Frequently Asked Questions

Nimotop contains nimodipine, a calcium channel blocker that is specifically indicated to prevent cerebral vasospasm after subarachnoid hemorrhage. By improving blood flow in the brain’s vessels, it helps reduce the risk of delayed ischemic neurological deficits in patients who have experienced this type of bleed.

Nimodipine selectively blocks L‑type calcium channels in the smooth muscle of cerebral arteries. This inhibition reduces calcium entry into the cells, causing vasodilation of the brain’s blood vessels. The resulting increase in cerebral blood flow helps protect neural tissue from ischemia following a subarachnoid hemorrhage.

The dosage of Nimotop is determined by the prescribing clinician based on the patient’s clinical condition, weight, and response. Health‑care professionals follow established guidelines and adjust the regimen as needed; patients should not alter the dose without medical advice.

The safety of Nimotop in pregnancy and lactation has not been definitively established. It is classified as pregnancy category unknown, and use is generally reserved for situations where the potential benefit justifies any possible risk to the fetus or infant. Consultation with a specialist is recommended.

To request Nimotop, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain requirements) and necessary import documentation.

Nimotop (nimodipine) is distinguished by its preferential action on cerebral vessels, whereas many other vasodilators affect systemic circulation more broadly. This selectivity makes it particularly effective for preventing vasospasm after subarachnoid hemorrhage, while other agents may be used for peripheral hypertension or angina.

Nimotop should be stored at temperatures below 25 °C, in its original packaging, and protected from moisture. Keep the product away from direct sunlight and do not store in a bathroom or other humid environment. No refrigeration is required for this oral tablet.

Nimotop is taken orally, usually as a tablet, with or without food as directed by the prescriber. The exact timing and frequency are individualized, and patients should follow the dosing schedule provided by their health‑care professional to maintain consistent drug levels.

The most serious adverse events include severe hypotension, bradycardia, hepatic dysfunction, and rare allergic reactions such as rash or anaphylaxis. Patients should be monitored for signs of these conditions, and any sudden changes in blood pressure or heart rate should prompt immediate medical evaluation.

Nimotop is contraindicated in patients with known hypersensitivity to nimodipine or any component of the formulation. It should also be avoided in individuals with severe hypotension or uncontrolled heart failure unless specifically directed by a specialist, as the drug’s vasodilatory effect may exacerbate these conditions.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.