Product image of Nimotop (Nimodipine) supplied by GNH India

Nimotop

Active Ingredient:
Nimodipine
Origin:
EU

Nimotop (Nimodipine)

Nimodipine, the active ingredient in Nimotop, is a calcium channel blocker presented as a 30 mg tablet for oral use. It treats and helps prevent cerebral vasospasm after subarachnoid hemorrhage and may be used in cerebral ischemia.
GNH India supplies Nimotop as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Laboratoire Xo

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Nimotop is a calcium channel blocker used in cerebrovascular conditions to improve outcomes.

  • Prevention of cerebral vasospasm after subarachnoid hemorrhage: reduces the incidence of delayed ischemic neurological deficits.
  • Cerebral ischemia: enhances cerebral blood flow in patients with reduced perfusion.
  • Management of subarachnoid hemorrhage complications: supports neurological recovery by maintaining adequate cerebral circulation.

How It Works

  • Nimodipine selectively blocks L‑type calcium channels in the smooth muscle of cerebral arteries, decreasing calcium influx. This antagonism leads to vasodilation of intracerebral vessels, increasing cerebral blood flow and oxygen delivery while limiting vasospasm after hemorrhagic events.

Side Effects

Nimotop may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Headache: mild to moderate intensity.
  • Flushing: transient warmth and redness of skin.
  • Hypotension: occasional drop in blood pressure.
  • Nausea: mild gastrointestinal upset.
  • Dizziness: sensation of light‑headedness.
  • Peripheral edema: swelling of lower limbs.

Serious or Rare Side Effects

  • Severe hypotension: marked blood pressure reduction requiring medical attention.
  • Myocardial infarction: rare cardiac event.
  • Arrhythmias: abnormal heart rhythms.
  • Hepatic dysfunction: elevated liver enzymes or jaundice.
  • Allergic reactions: rash, Stevens‑Johnson syndrome, or anaphylaxis.
  • Thrombocytopenia: low platelet count.

Precautions & Warnings

Before initiating Nimotop, clinicians should evaluate patient‑specific factors and monitor for potential complications.

  • Renal or hepatic impairment: adjust monitoring as needed.
  • Hypotension: observe blood pressure, especially with other antihypertensives.
  • Concomitant nitrates: avoid combined use due to additive vasodilatory effect.
  • Pregnancy and lactation: use only if benefit outweighs risk, as safety is not established.
  • Elderly patients: consider lower starting dose and monitor for dizziness.
  • Store at ambient temperature: keep below 25°C, retain in original packaging, protect from moisture and light.

Avoid Interactions

Nimotop can interact with several drug classes, requiring careful management.

Major Interactions (Avoid)

  • Concomitant use with other potent vasodilators (e.g., nitroglycerin): may cause severe hypotension.
  • Strong CYP3A4 inhibitors (e.g., ketoconazole, clarithromycin): increase nimodipine plasma concentrations.
  • Strong CYP3A4 inducers (e.g., rifampicin, carbamazepine): reduce therapeutic efficacy.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: may enhance bradycardia.
  • Diuretics: may potentiate hypotensive effect.
  • Anticoagulants: monitor for bleeding if hypotension occurs.

Frequently Asked Questions

Nimotop contains the active ingredient nimodipine and is indicated for the prevention of cerebral vasospasm following subarachnoid hemorrhage, as well as for improving cerebral blood flow in patients with cerebral ischemia. These uses aim to reduce delayed neurological deficits and support recovery after hemorrhagic or ischemic brain events.

Nimodipine is an L‑type calcium channel antagonist. By blocking calcium entry into the smooth muscle cells of cerebral arteries, it causes selective vasodilation of intracerebral vessels, thereby increasing cerebral perfusion and reducing the risk of vasospasm after bleeding into the subarachnoid space.

The exact dose of Nimotop is determined by the prescribing physician based on the individual patient's condition and clinical guidelines. Typically, the medication is administered orally as a tablet taken twice daily, but the prescriber’s specific order should always be followed.

Safety data for nimodipine in pregnancy and lactation are limited, and the product is classified as having an unknown pregnancy category. It should be used only when the potential benefit to the mother outweighs any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare professional.

To order Nimotop, submit an enquiry on the product page at gnhindia.com, indicating the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any required cold‑chain handling) and the necessary import documentation.

Nimodipine is specifically designed to cross the blood‑brain barrier, providing targeted cerebral vasodilation, whereas many other dihydropyridine calcium channel blockers such as amlodipine primarily affect systemic vascular beds and are not indicated for preventing cerebral vasospasm. This pharmacokinetic property makes nimodipine the preferred choice for neurovascular indications.

Nimotop tablets should be stored at ambient temperature below 25 °C, in the original blister pack, protected from moisture, light and heat. Keep the medication out of reach of children and do not use it after the printed expiry date.

Nimotop is taken orally as a whole tablet, usually with or without food as directed by the prescriber. Swallow the tablet with a glass of water; do not crush, chew, or split the tablet unless specifically instructed by a healthcare professional.

Serious adverse reactions can include severe hypotension, myocardial infarction, cardiac arrhythmias, hepatic dysfunction, and allergic reactions such as Stevens‑Johnson syndrome or anaphylaxis. Patients should seek immediate medical attention if they experience chest pain, fainting, unexplained rash, jaundice, or any sudden change in health status.

Nimotop should be avoided in individuals with known hypersensitivity to nimodipine or other dihydropyridine calcium channel blockers, patients with severe hypotension, and those taking contraindicated vasodilators. Caution is also advised for patients with significant liver impairment, and the drug should be used only under medical supervision in such cases.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.