Product image of Nintedanib Newbury (Nintedanib) supplied by GNH India

Nintedanib Newbury

Active Ingredient:
Nintedanib
Origin:
EU

Nintedanib Newbury (Nintedanib)

Nintedanib, the active ingredient in Nintedanib Newbury, is a tyrosine kinase inhibitor presented as an oral formulation for oral use. It is indicated for the treatment of idiopathic pulmonary fibrosis, systemic sclerosis‑associated interstitial lung disease, and in combination therapy for non‑small cell lung cancer, helping to slow disease progression in these conditions.\n\nGNH India supplies Nintedanib Newbury as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, oncology centres and pharmacies worldwide.

Manufacturer / TM Owner

Newbury Pharmaceuticals Ab

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Nintedanib is used to target fibrotic and oncologic pathways in several serious lung disorders.\n\n- Idiopathic pulmonary fibrosis: slows decline in forced vital capacity, reduces exacerbation rate, and helps preserve quality of life.\n- Systemic sclerosis‑associated interstitial lung disease: helps maintain lung volumes, delays fibrosis progression, and may improve functional outcomes.\n- Non‑small cell lung cancer (in combination therapy): adds anti‑angiogenic activity to chemotherapy, contributing to disease control and potentially extending survival.

How It Works

  • Nintedanib inhibits multiple receptor tyrosine kinases—including vascular endothelial growth factor receptors (VEGFR 1‑3), fibroblast growth factor receptors (FGFR 1‑3), and platelet‑derived growth factor receptors (PDGFR‑α/β). By blocking these pathways, it reduces endothelial cell proliferation, fibroblast activation, and angiogenesis, thereby limiting fibrotic tissue formation and tumor vascularization. The simultaneous inhibition of these three receptor families curtails downstream signaling cascades such as MAPK and PI3K/AKT, which are critical for cell migration, extracellular matrix deposition, and neovascular growth.

Side Effects

  • Nintedanib may be associated with a range of adverse reactions, which are categorized by frequency and severity.\n\nCommon Side Effects:\n- Diarrhea: frequent loose stools that may be mild, moderate, or occasionally severe and can lead to dehydration.\n- Nausea: a sensation of sickness that may be transient or persist, sometimes accompanied by loss of appetite.\n- Elevated liver enzymes: mild to moderate increases in alanine aminotransferase (ALT) and aspartate aminotransferase (AST) observed in laboratory tests.\n\nSerious or Rare Side Effects:\n- Hepatotoxicity: clinically significant liver injury that may present with jaundice, elevated bilirubin, or hepatic failure.\n- Bleeding events: gastrointestinal hemorrhage or other serious bleeding that may require medical intervention.\n- Severe infections: opportunistic or serious infections, including pneumonia, that can occur in patients with compromised immunity.

Precautions & Warnings

  • When prescribing Nintedanib, clinicians should consider several precautionary measures to minimize risk and ensure safe use.\n\n- Liver function monitoring: assess baseline ALT/AST and bilirubin,

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Nintedanib

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT