Ninur

Active Ingredient:: Nitrofurantoin
Origin:: EU

Ninur (Nitrofurantoin)

Q: What is Ninur used for?

Ninur contains nitrofurantoin, an antibiotic indicated for the treatment of uncomplicated urinary tract infections caused by susceptible bacteria, and it can also be used for prophylaxis of recurrent infections when prescribed by a qualified healthcare professional.

Q: How does nitrofurantoin work?

Nitrofurantoin is reduced inside bacterial cells to reactive intermediates that damage DNA, ribosomal proteins and enzymes involved in carbohydrate metabolism, leading to bacterial cell death while having limited activity in human cells.

Q: What is the usual dose of Ninur?

The dosage of Ninur is determined by the prescribing clinician based on the patient’s condition, renal function and local treatment guidelines. Patients should follow the exact regimen provided by their healthcare professional.

Q: Is Ninur safe during pregnancy or breastfeeding?

Safety of nitrofurantoin in pregnancy and lactation depends on the trimester and individual risk factors. It should only be used when the potential benefit justifies any possible risk, and the decision must be made by the treating physician.

Q: How do I order Ninur from GNH India?

To request Ninur, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Q: How does Ninur compare with other urinary antiseptics?

Ninur (nitrofurantoin) is a nitrofuran antibiotic that concentrates in urine, offering targeted activity against common uropathogens. Compared with trimethoprim‑sulfamethoxazole or fluoroquinolones, nitrofurantoin has a lower risk of promoting resistance but is contraindicated in patients with reduced renal function.

Q: How should Ninur be stored and handled?

Ninur tablets should be stored at ambient temperature, below 25 °C, in the original container to protect them from moisture and light. Keep the product out of reach of children and do not use after the expiry date.

Q: How is Ninur administered?

Ninur is taken orally, usually with a full glass of water. It may be taken with food or on an empty stomach, depending on the prescriber’s instructions, to improve tolerability and absorption.

Q: What are the most serious risks associated with Ninur?

Serious adverse events include pulmonary toxicity (interstitial pneumonitis or fibrosis), hepatic injury, severe allergic reactions such as anaphylaxis, hemolytic anemia in patients with G6PD deficiency, peripheral neuropathy and agranulocytosis. Prompt medical attention is required if any of these occur.

Q: Who should not use Ninur?

Ninur should be avoided in patients with severe renal impairment (creatinine clearance <60 mL/min), known hypersensitivity to nitrofurantoin, G6PD deficiency, or in those who are pregnant in the first trimester unless the benefits outweigh the risks. Clinicians should assess each patient individually.

Nitrofurantoin, the active ingredient in Ninur, is a nitrofuran antibiotic presented as an oral tablet for systemic use. It is indicated for the treatment of uncomplicated urinary tract infections caused by susceptible bacteria, primarily in adult patients.

GNH India supplies Ninur as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, ensuring quality‑assured products and reliable logistics for global healthcare providers. The product complies with European Union pharmacopeial standards and is manufactured under GMP conditions. It is distributed through GNH India's established network to meet the needs of diverse markets.

Manufacturer / TM Owner

Belupo D.D.

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Indications & Clinical Uses

Nitrofurantoin is used primarily for infections of the urinary tract caused by susceptible bacteria.

Uncomplicated urinary tract infection: eradicates the causative bacteria and resolves dysuria, frequency and urgency.
Acute cystitis: provides rapid symptom relief and bacterial clearance in adult women.
Recurrent urinary tract infection prophylaxis: reduces the frequency of new infections when administered over a prolonged period.

How It Works

Nitrofurantoin is reduced by bacterial flavoproteins to reactive intermediates that damage bacterial DNA, ribosomal proteins and enzymes involved in carbohydrate metabolism. This multi‑targeted attack disrupts essential cellular processes, leading to bacterial cell death while sparing most human cells due to limited drug activation in mammalian tissues.

Side Effects

Adverse reactions may occur with nitrofurantoin therapy and vary in frequency and severity.

Common Side Effects

Nausea: mild to moderate upset stomach.
Loss of appetite: reduced desire to eat.
Headache: transient cranial discomfort.
Diarrhea: loose stools, usually self‑limiting.
Metallic taste: transient alteration of taste perception.
Mild skin rash: localized erythema or itching.

Serious or Rare Side Effects

Pulmonary toxicity: interstitial pneumonitis or fibrosis, potentially life‑threatening.
Hepatic injury: jaundice, elevated liver enzymes.
Severe allergic reactions: anaphylaxis, angioedema.
Hemolytic anemia: especially in patients with G6PD deficiency.
Peripheral neuropathy: numbness or tingling in extremities.
Agranulocytosis: marked reduction in white blood cells.

Precautions & Warnings

Before initiating nitrofurantoin, clinicians should consider several safety aspects.

Renal function assessment: avoid use in patients with creatinine clearance <60 mL/min.
Pregnancy and lactation: use only if benefits outweigh potential risks.
G6PD deficiency: contraindicated due to risk of hemolysis.
Long‑term therapy: monitor for pulmonary or hepatic toxicity.
Concomitant nephrotoxic drugs: exercise caution to prevent renal impairment.
Store at ambient temperature: keep below 25 °C, retain in original packaging, protect from moisture and direct sunlight.

Avoid Interactions

Nitrofurantoin may interact with other medicines, altering its efficacy or safety.

Major Interactions (Avoid)

Antacids containing magnesium or aluminum: reduce nitrofurantoin absorption.
Probenecid: increases nitrofurantoin plasma concentrations, raising toxicity risk.
Warfarin: may potentiate anticoagulant effect, requiring INR monitoring.
Methenamine: concurrent use can diminish antimicrobial activity.

Moderate Interactions (Monitor Closely)

NSAIDs: combined renal stress may impair kidney function.
Diuretics: altered urinary concentration can affect drug excretion.
Fluoroquinolones: concurrent use may increase risk of tendon disorders.

Frequently Asked Questions

Ninur contains nitrofurantoin, an antibiotic indicated for the treatment of uncomplicated urinary tract infections caused by susceptible bacteria, and it can also be used for prophylaxis of recurrent infections when prescribed by a qualified healthcare professional.

Nitrofurantoin is reduced inside bacterial cells to reactive intermediates that damage DNA, ribosomal proteins and enzymes involved in carbohydrate metabolism, leading to bacterial cell death while having limited activity in human cells.

The dosage of Ninur is determined by the prescribing clinician based on the patient’s condition, renal function and local treatment guidelines. Patients should follow the exact regimen provided by their healthcare professional.

Safety of nitrofurantoin in pregnancy and lactation depends on the trimester and individual risk factors. It should only be used when the potential benefit justifies any possible risk, and the decision must be made by the treating physician.

To request Ninur, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Ninur (nitrofurantoin) is a nitrofuran antibiotic that concentrates in urine, offering targeted activity against common uropathogens. Compared with trimethoprim‑sulfamethoxazole or fluoroquinolones, nitrofurantoin has a lower risk of promoting resistance but is contraindicated in patients with reduced renal function.

Ninur tablets should be stored at ambient temperature, below 25 °C, in the original container to protect them from moisture and light. Keep the product out of reach of children and do not use after the expiry date.

Ninur is taken orally, usually with a full glass of water. It may be taken with food or on an empty stomach, depending on the prescriber’s instructions, to improve tolerability and absorption.

Serious adverse events include pulmonary toxicity (interstitial pneumonitis or fibrosis), hepatic injury, severe allergic reactions such as anaphylaxis, hemolytic anemia in patients with G6PD deficiency, peripheral neuropathy and agranulocytosis. Prompt medical attention is required if any of these occur.

Ninur should be avoided in patients with severe renal impairment (creatinine clearance <60 mL/min), known hypersensitivity to nitrofurantoin, G6PD deficiency, or in those who are pregnant in the first trimester unless the benefits outweigh the risks. Clinicians should assess each patient individually.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated: 27 Sep 2026

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