Product image of Nipin (Nifedipine) supplied by GNH India

Nipin

Active Ingredient:
Nifedipine
Origin:
EU

Nipin (Nifedipine)

Nifedipine, the active ingredient in Nipin, is a calcium channel blocker presented as an oral tablet for oral use. It treats hypertension, angina pectoris and Raynaud's phenomenon in adult patients.\n\nGNH India supplies Nipin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Lab. It. Biochim. Farm.Co Lisapharma S.P.A.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

  • Nifedipine acts on the cardiovascular system to lower blood pressure and improve myocardial oxygen supply.\n\nHypertension: reduces systemic vascular resistance and lowers blood pressure.\nAngina pectoris: decreases cardiac workload and prevents chest pain episodes.\nRaynaud's phenomenon: enhances peripheral blood flow and reduces frequency of vasospastic attacks.

How It Works

  • Nifedipine selectively blocks L‑type calcium channels in vascular smooth muscle and myocardial cells, inhibiting calcium influx. This causes relaxation of arterial smooth muscle, leading to vasodilation, decreased peripheral resistance, and reduced cardiac after‑load, thereby lowering blood pressure and myocardial oxygen demand.

Side Effects

  • Nifedipine may cause a range of adverse reactions, from mild to severe.\n\nCommon Side Effects:\n- Headache\n- Flushing\n- Peripheral edema\n- Dizziness\n\nSerious or Rare Side Effects:\n- Severe hypotension\n- Allergic reactions such as rash or anaphylaxis

Precautions & Warnings

  • Before initiating therapy, clinicians should consider several safety measures.\n\nMonitor blood pressure regularly: ensure target levels are achieved without excessive drop.\nAvoid abrupt discontinuation: taper dose to prevent rebound hypertension.\nUse caution in hepatic impairment: dose adjustment may be required.\nAvoid concurrent strong CYP3A4 inhibitors: may increase nifedipine exposure.\nUse with caution in patients with heart failure: monitor for worsening symptoms.\nStore at room temperature: keep in the original container, protect from moisture and direct sunlight.

Avoid Interactions

  • Nifedipine can interact with other medicines, altering its effectiveness or safety.\n\nMajor Interactions (Avoid):\n- Grapefruit juice: markedly increases plasma concentrations.\n- Strong CYP3A4 inhibitors (e.g., ketoconazole, ritonavir): may cause toxicity.\n- Concurrent use with other potent antihypertensives: risk of severe hypotension.\n\nModerate Interactions (Monitor Closely):\n- CYP3A4 inducers (e.g., rifampicin, carbamazepine): may reduce efficacy.\n- Diuretics: may enhance hypotensive effect.\n- Digoxin: may increase serum digoxin levels, requiring monitoring.

Frequently Asked Questions

Nipin contains nifedipine, which is prescribed for managing hypertension, relieving angina pectoris, and reducing the frequency of attacks in Raynaud's phenomenon. These uses reflect its ability to dilate blood vessels and lower cardiac workload.

Nifedipine blocks L‑type calcium channels in vascular smooth muscle and heart muscle, preventing calcium entry. This leads to relaxation of arterial walls, vasodilation, decreased peripheral resistance, and reduced myocardial oxygen demand, which helps control blood pressure and chest pain.

The appropriate dose of Nipin is determined by the prescribing clinician based on the individual’s medical condition, response to therapy, and other factors. Patients should follow the dosage instructions provided by their healthcare professional.

The safety of nifedipine in pregnancy and lactation has not been definitively established. Healthcare providers should weigh potential benefits against possible risks before prescribing Nipin to pregnant or nursing women.

To request Nipin, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Nipin (nifedipine) belongs to the calcium channel blocker class, which primarily causes arterial vasodilation. Compared with beta‑blockers or ACE inhibitors, nifedipine may produce faster blood‑pressure reduction but can be associated with peripheral edema. Choice of therapy depends on patient profile and comorbidities.

Nipin should be stored at room temperature, below 25 °C, in its original packaging. Keep the product away from moisture, heat and direct sunlight to maintain its stability and potency.

Nipin is taken orally, usually with a glass of water. The tablet should be swallowed whole and not chewed or crushed unless specifically instructed by a healthcare professional.

Serious risks include severe hypotension, which can cause fainting or shock, and allergic reactions such as rash, swelling or anaphylaxis. Patients should seek immediate medical attention if they experience sudden dizziness, rapid heartbeat, or signs of an allergic response.

Nipin is contraindicated in patients with known hypersensitivity to nifedipine or other dihydropyridine calcium channel blockers, and in those with severe aortic stenosis or uncontrolled heart failure. Clinicians should evaluate each patient’s medical history before prescribing.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.