Product image of Niquitin Fruit (Nicotine Resinate) supplied by GNH India

Niquitin Fruit

Active Ingredient:
Nicotine Resinate
Origin:
EU

Niquitin Fruit (Nicotine Resinate)

Nicotine Resinate, the active ingredient in Niquitin Fruit, is a nicotine replacement therapy presented as an oromucosal formulation for oral use. It delivers nicotine through the mucous membranes to alleviate withdrawal symptoms and cravings in adult smokers who are attempting to quit, supporting a gradual reduction in nicotine dependence.

GNH India supplies Niquitin Fruit as a licensed, GDP‑compliant international pharmaceutical supplier serving pharmacies worldwide. The company provides reliable sourcing, regulatory support, and global logistics to meet the needs of healthcare providers.

Manufacturer / TM Owner

Perrigo Poland Sp. Z.O.O.

1
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Indications & Clinical Uses

  • Niquitin Fruit, a nicotine replacement therapy, is used to manage nicotine dependence and support smoking cessation.
  • Smoking cessation: helps adult smokers reduce withdrawal symptoms and quit tobacco use.
  • Nicotine dependence: provides controlled nicotine delivery to lessen cravings during a quit attempt.
  • Relapse prevention: assists individuals who have quit smoking to maintain abstinence by managing occasional urges.

How It Works

  • Nicotine Resinate acts as an agonist at nicotinic acetylcholine receptors in the central and peripheral nervous system. By stimulating these receptors, it mimics the pharmacological effects of nicotine, thereby reducing the intensity of withdrawal symptoms and cravings associated with abrupt cessation. The oromucosal route allows rapid absorption through the oral mucosa, providing a steady plasma nicotine level that facilitates a gradual tapering of nicotine intake.

Side Effects

Niquitin Fruit may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Mouth irritation or soreness
  • Nausea or upset stomach
  • Hiccups or throat discomfort
  • Dizziness or light‑headedness
  • Headache
  • Increased salivation

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis)
  • Chest pain or tightness
  • Rapid heartbeat (tachycardia)
  • High blood pressure spikes
  • Seizures
  • Severe skin rash or Stevens‑Johnson syndrome

Precautions & Warnings

  • Before using Niquitin Fruit, consider the following safety measures.
  • Assess nicotine dependence level: evaluate patient’s smoking history before initiating therapy.
  • Avoid use in individuals with recent myocardial infarction: consult a physician.
  • Monitor for cardiovascular symptoms: watch for chest pain or palpitations.
  • Do not use concurrently with other nicotine replacement products: risk of nicotine overdose.
  • Store below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Niquitin Fruit can interact with certain medicines; awareness helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): may increase risk of hypertensive crisis.
  • Other nicotine‑containing products: risk of nicotine toxicity.
  • CYP2A6 inhibitors: can raise nicotine plasma levels.

Moderate Interactions (Monitor Closely)

  • Antidepressants (SSRIs): may alter nicotine metabolism.
  • Beta‑blockers: may mask tachycardia symptoms.
  • Alcohol: can enhance nicotine’s cardiovascular effects.

Frequently Asked Questions

Niquitin Fruit is an oromucosal nicotine replacement product used to help adult smokers quit by reducing nicotine withdrawal symptoms and cravings during a smoking cessation attempt.

Nicotine Resinate binds to nicotinic acetylcholine receptors in the brain, providing a controlled nicotine stimulus that mimics the effect of tobacco nicotine, thereby easing withdrawal and decreasing the urge to smoke.

The appropriate dose is determined by the prescribing healthcare professional based on the individual’s smoking history, level of dependence, and clinical response. Patients should follow the prescriber’s instructions exactly.

Safety data for Nicotine Resinate in pregnancy and lactation are limited. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks with their healthcare provider before using the product.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with nicotine patches or gum, Niquitin Fruit delivers nicotine through the oral mucosa, offering faster absorption and flexible dosing. It may be preferred by patients who want rapid relief of cravings, while patches provide a slower, steady release over 24 hours.

Store the product below 25 °C in its original packaging, protected from moisture and direct sunlight. Keep out of reach of children and do not use if the packaging is damaged or the product appears discoloured.

The product is placed in the mouth and allowed to dissolve slowly against the oral mucosa, following the prescriber’s instructions. It should not be swallowed whole; the mucosal surface should be in contact with the formulation for optimal absorption.

Serious adverse events include severe allergic reactions such as anaphylaxis, chest pain, rapid heartbeat, high blood pressure spikes, seizures, and severe skin reactions. Patients experiencing any of these should seek immediate medical attention.

Individuals with known hypersensitivity to nicotine resinate or any excipients, those who have recently experienced a myocardial infarction or severe cardiovascular disease, and patients already using other nicotine‑containing products should avoid using Niquitin Fruit unless directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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