Product image of Niquitin Fruit (Nicotine Resinate) supplied by GNH India

Niquitin Fruit

Active Ingredient:
Nicotine Resinate
Origin:
EU

Niquitin Fruit (Nicotine Resinate)

Nicotine resinate, the active ingredient in Niquitin Fruit, is a nicotine replacement therapy presented as an oromucosal product for oromucosal use. It helps adult smokers who wish to reduce or quit nicotine dependence.

GNH India supplies Niquitin Fruit as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Richard Bittner Ag,

1
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Indications & Clinical Uses

Niquitin Fruit is used as a nicotine replacement to support smoking cessation and manage nicotine dependence.

  • Smoking cessation: assists adult smokers in reducing cravings and withdrawal symptoms.
  • Nicotine dependence: supports gradual reduction of nicotine intake.
  • Tobacco cessation programs: used as part of comprehensive cessation plans.

How It Works

  • Nicotine resinate dissociates in the oral mucosa, releasing nicotine that binds to nicotinic acetylcholine receptors in the central nervous system. This stimulation reduces withdrawal symptoms and cravings by mimicking the pharmacologic effects of tobacco‑derived nicotine while delivering a controlled dose through the oromucosal route.

Side Effects

Niquitin Fruit may cause a range of adverse reactions.

Common Side Effects

  • Mouth irritation or soreness.
  • Nausea or upset stomach.
  • Dizziness or light‑headedness.
  • Headache.
  • Increased salivation.
  • Hiccups.

Serious or Rare Side Effects

  • Cardiovascular events such as hypertension or arrhythmia.
  • Severe allergic reactions including rash, swelling, or anaphylaxis.
  • Respiratory depression.
  • Seizures.
  • Hypotension.
  • Persistent vomiting.

Precautions & Warnings

When using Niquitin Fruit, consider the following precautions.

  • Cardiovascular assessment: evaluate patients with recent myocardial infarction or unstable angina.
  • Hypertension monitoring: avoid use in uncontrolled high blood pressure.
  • Allergy screening: watch for signs of hypersensitivity.
  • Pregnancy and lactation: use only if clearly needed and prescribed.
  • Concomitant nicotine products: do not combine with other nicotine replacement therapies.
  • Store at room temperature: keep in the original packaging, protect from moisture and direct heat.

Avoid Interactions

Niquitin Fruit can interact with several drug classes.

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): increased risk of hypertensive crisis.
  • Other nicotine replacement products: potential nicotine overdose.
  • CYP2A6 inhibitors: elevated nicotine plasma levels.

Moderate Interactions (Monitor Closely)

  • Antidepressants (e.g., SSRIs): may alter nicotine metabolism.
  • Antihypertensive agents: nicotine may reduce their efficacy.
  • Theophylline: possible increase in plasma concentration.
  • Beta‑blockers: may blunt nicotine‑induced tachycardia.
  • Anticoagulants: nicotine may affect platelet function.

Frequently Asked Questions

Niquitin Fruit contains nicotine resinate and is used as a nicotine replacement therapy to help adult smokers reduce cravings and manage withdrawal symptoms during smoking cessation efforts.

Nicotine resinate releases nicotine when applied to the oral mucosa. The nicotine binds to nicotinic acetylcholine receptors in the brain, providing a controlled stimulant effect that lessens withdrawal and craving without the harmful constituents of tobacco smoke.

The appropriate dose of Niquitin Fruit is determined by the prescribing healthcare professional based on the individual’s smoking history, dependence level, and overall health status.

Safety in pregnancy or lactation has not been fully established. It should only be used if the potential benefit justifies the potential risk, and this decision must be made by a qualified healthcare provider.

To place an order, submit an enquiry on the product page at gnhindia.com with the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Niquitin Fruit delivers nicotine via an oromucosal route, offering rapid absorption similar to other oral nicotine products but without the need for chewing or inhalation. Compared with patches, it provides quicker onset of action, while dosing can be more easily titrated than lozenges.

Store Niquitin Fruit at room temperature, below 25 °C. Keep it in the original packaging, protect it from moisture, direct sunlight and excessive heat to maintain product stability.

Niquitin Fruit is applied to the oral mucosa according to the prescriber’s instructions. The patient places the product in the mouth and allows it to dissolve, ensuring contact with the mucosal surface for optimal nicotine absorption.

Serious risks include cardiovascular events such as hypertension or arrhythmia, severe allergic reactions (including anaphylaxis), respiratory depression, and seizures. Patients should seek immediate medical attention if any of these occur.

Niquitin Fruit should be avoided by individuals with known hypersensitivity to nicotine resinate, those who have recently experienced a myocardial infarction or unstable angina, and patients for whom nicotine use is contraindicated, unless a healthcare professional determines otherwise.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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