Product image of Niquitin Lozenge (Nicotine) supplied by GNH India

Niquitin Lozenge

Active Ingredient:
Nicotine
Origin:
EU

Niquitin Lozenge (Nicotine)

Nicotine, the active ingredient in Niquitin Lozenge, is a nicotine drug presented as an oral lozenge for oromucosal use. It is used to help adult smokers manage nicotine withdrawal and support smoking cessation efforts, reducing dependence on tobacco.
GNH India supplies Niquitin Lozenge as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to European Union quality standards and provides regulatory‑compliant shipments to a global customer base.

Manufacturer / TM Owner

Perrigo Belgium Nv

1
Pack/s
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Indications & Clinical Uses

  • Niquitin Lozenge, a nicotine replacement therapy, is indicated for conditions related to tobacco dependence.
  • Smoking cessation: assists adult smokers in quitting by reducing nicotine cravings.
  • Nicotine dependence: alleviates withdrawal symptoms during quit attempts.
  • Tobacco use disorder: supports gradual reduction of nicotine intake as part of a cessation program.

How It Works

  • Nicotine lozenges deliver nicotine to the oral mucosa, where it is absorbed into the bloodstream. The nicotine binds to nicotinic acetylcholine receptors in the central nervous system, partially stimulating these receptors and mimicking the effect of tobacco‑derived nicotine. This reduces the intensity of withdrawal symptoms and cravings, allowing the user to taper nicotine exposure while maintaining a level of receptor activation that eases the transition away from smoking.

Side Effects

Niquitin Lozenge may cause a range of adverse reactions, most of which are mild and transient.

Common Side Effects

  • Mouth irritation
  • Nausea
  • Heartburn
  • Hiccups
  • Increased salivation
  • Bad taste

Serious or Rare Side Effects

  • Severe allergic reaction (anaphylaxis)
  • Persistent dizziness
  • Chest pain
  • Irregular heartbeat
  • Severe nausea or vomiting
  • High blood pressure

Precautions & Warnings

  • When using Niquitin Lozenge, certain precautions should be observed to ensure safe and effective use.
  • Assess suitability: confirm the patient is an adult smoker seeking cessation.
  • Avoid use in non‑smokers: nicotine can cause dependence.
  • Limit duration: follow prescriber guidance to prevent prolonged nicotine exposure.
  • Monitor cardiovascular status: nicotine may affect heart rate and blood pressure.
  • Avoid concurrent use with other nicotine products: may increase total nicotine dose.
  • Store below 25°C: keep in the original pack, protect from moisture.

Avoid Interactions

Niquitin Lozenge can interact with other medicines, altering their effects or increasing side‑effect risk.

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): may enhance hypertensive response.
  • Uncontrolled hypertension: nicotine can raise blood pressure.
  • Recent myocardial infarction or unstable angina: nicotine may increase cardiac workload.

Moderate Interactions (Monitor Closely)

  • Antidepressants (SSRIs, SNRIs): monitor for increased anxiety.
  • Anticoagulants (warfarin): nicotine may affect platelet function.
  • Caffeine: nicotine can potentiate stimulant effects.
  • Diabetes medications: nicotine may affect glucose control.

Frequently Asked Questions

Niquitin Lozenge is an oral nicotine replacement product used to help adult smokers manage cravings and withdrawal symptoms during a quit attempt. It provides a controlled dose of nicotine to reduce dependence on tobacco and supports the overall smoking cessation process.

The lozenge releases nicotine onto the oral mucosa, where it is absorbed into the bloodstream. Nicotine then binds to nicotinic acetylcholine receptors in the brain, partially stimulating them and mimicking the effect of cigarette‑derived nicotine, which lessens cravings and withdrawal discomfort.

The exact dosing regimen is determined by the prescriber based on the individual’s smoking history and dependence level. A healthcare professional will select the appropriate strength and frequency, typically starting with a low dose and adjusting as needed during the cessation program.

Safety of nicotine lozenges in pregnancy and lactation has not been fully established. Women who are pregnant, planning to become pregnant, or breastfeeding should discuss potential risks with their healthcare provider before using the product.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details and any necessary import documentation.

Compared with nicotine patches, the lozenge offers rapid absorption through the oral mucosa, allowing flexible dosing and immediate relief of cravings. Unlike nicotine gum, the lozenge does not require chewing, which some users find more comfortable. Choice depends on personal preference, dosing needs and clinician recommendation.

Store the lozenges below 25°C in their original packaging, protecting them from moisture and direct sunlight. Keep out of reach of children and do not use if the packaging is damaged or the product appears discoloured.

Place one lozenge in the mouth and allow it to dissolve slowly, moving it occasionally from cheek to gum. Do not chew or swallow whole. Avoid eating or drinking for at least 15 minutes before and after use to ensure optimal nicotine absorption.

Serious risks, though rare, include severe allergic reactions such as anaphylaxis, persistent dizziness, chest pain, irregular heartbeat, severe nausea or vomiting, and significant increases in blood pressure. Users should seek immediate medical attention if any of these symptoms occur.

The lozenge is contraindicated for non‑smokers, children, adolescents, pregnant or breastfeeding women without medical advice, and individuals with uncontrolled hypertension, recent myocardial infarction, unstable angina, or severe cardiovascular disease. Anyone with known hypersensitivity to nicotine should also avoid use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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