Product image of Niquitin (Nicotine) supplied by GNH India

Niquitin

Active Ingredient:
Nicotine
Origin:
EU

Niquitin (Nicotine)

Nicotine, the active ingredient in Niquitin, is a nicotinic agonist presented as a transdermal patch for transdermal use. It is indicated for adult smokers who wish to quit, helping to alleviate nicotine withdrawal symptoms and reduce cravings during cessation attempts.

GNH India supplies Niquitin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, with distribution aligned to EU regulatory standards. The product meets European pharmacopoeial specifications and is manufactured under GMP conditions, ensuring consistent performance throughout its shelf life.

Manufacturer / TM Owner

Perrigo Poland Sp. Z.O.O.

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Indications & Clinical Uses

Niquitin (nicotine) is used in smoking cessation therapy to address nicotine dependence.

  • Smoking cessation: supports adult smokers in quitting by mitigating withdrawal and cravings.
  • Nicotine dependence: reduces physiological need for nicotine in regular tobacco users.
  • Relapse prevention: helps maintain abstinence after initial quitting by providing controlled nicotine exposure.

How It Works

  • Nicotine in Niquitin binds to neuronal nicotinic acetylcholine receptors, primarily the α4β2 subtype, leading to modest dopamine release that eases withdrawal symptoms. Continuous transdermal delivery maintains stable plasma nicotine levels, decreasing the urge to smoke and attenuating the reinforcing effects of tobacco nicotine.

Side Effects

Common Side Effects

  • Skin irritation at the application site: redness, itching, or rash.
  • Insomnia: difficulty falling or staying asleep.
  • Vivid dreams: unusually intense or disturbing dreams.
  • Nausea: feeling of stomach upset.
  • Headache: mild to moderate head discomfort.
  • Dizziness: sensation of light‑headedness.

Serious or Rare Side Effects

  • Allergic reaction: swelling, hives, or difficulty breathing.
  • Severe skin reaction: blistering or extensive dermatitis.
  • Tachycardia: abnormally fast heart rate.
  • Hypertension: elevated blood pressure.
  • Seizures: rare occurrence of convulsive episodes.

Precautions & Warnings

Before using Niquitin, consider the following safety measures.

  • Cardiovascular assessment: evaluate history of heart disease or recent myocardial infarction.
  • Lowest effective dose: start with the smallest patch strength that provides symptom relief.
  • Non‑smoker use: avoid use in individuals who do not regularly smoke.
  • Pregnancy and lactation: only use if benefits outweigh potential risks.
  • Psychiatric monitoring: watch for mood changes or increased anxiety.
  • Store at room temperature: keep in the original packaging, protect from moisture and direct heat.

Avoid Interactions

Niquitin may interact with other medicines; review the following.

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): may increase risk of hypertensive crisis.
  • Concurrent nicotine products (gum, lozenge, inhaler): can cause nicotine overdose.

Moderate Interactions (Monitor Closely)

  • Antihypertensive agents: additive blood pressure‑lowering effect.
  • CYP2A6 inhibitors (e.g., certain antiretrovirals): may raise nicotine plasma levels.
  • Bupropion: combined use may raise seizure risk, requiring careful monitoring.

Frequently Asked Questions

Niquitin is a nicotine transdermal patch indicated for smoking cessation. It helps adult smokers reduce withdrawal symptoms and cravings, supporting the process of quitting tobacco use.

Nicotine in the patch binds to nicotinic acetylcholine receptors in the brain, especially the α4β2 subtype, producing a modest dopamine release that eases withdrawal and diminishes the urge to smoke.

The prescribed dose of Niquitin is determined by the treating clinician based on the individual’s smoking history, dependence level, and previous response to nicotine replacement therapy.

Use of Niquitin in pregnancy or while breastfeeding should only occur if the prescriber judges that the potential benefits outweigh any possible risks to the fetus or infant.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Niquitin delivers nicotine continuously through the skin, providing steadier plasma levels than short‑acting forms such as gum or lozenges. This can result in smoother symptom control, though choice depends on patient preference, smoking pattern and clinical guidance.

Store the patch at room temperature, preferably below 25 °C, in its original sealed pouch. Keep it away from moisture, direct sunlight and heat sources to maintain patch integrity.

The patch is applied to clean, dry, hair‑free skin on the upper arm, chest, or back. Press firmly for several seconds, then replace it with a new patch according to the prescriber’s schedule, typically every 24 hours.

Serious risks include severe skin reactions, allergic responses, tachycardia, hypertension, and, rarely, seizures. Patients should seek immediate medical attention if they experience any signs of an allergic reaction or cardiovascular symptoms.

Niquitin is contraindicated for non‑smokers, individuals with recent myocardial infarction or unstable heart disease, and those who are allergic to nicotine or any patch components.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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