Product image of Niquitin (Nicotine) supplied by GNH India

Niquitin

Active Ingredient:
Nicotine
Origin:
EU

Niquitin (Nicotine)

Nicotine, the active ingredient in Niquitin, is a nicotinic receptor agonist presented as a transdermal patch for transdermal use. It treats nicotine dependence and aids smoking cessation in adult smokers, helping to alleviate withdrawal symptoms and reduce cravings. Niquitin is marketed in the European Union as an over‑the‑counter product and is supplied in a ready‑to‑apply patch format.

GNH India supplies Niquitin as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Omega Pharma Ltd

1
Pack/s
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Indications & Clinical Uses

Niquitin is a nicotine replacement therapy that acts on the nicotinic acetylcholine receptor system to support cessation of tobacco use.

  • Smoking cessation: helps adult smokers quit by reducing withdrawal symptoms and cravings.
  • Nicotine dependence: alleviates physiological dependence on nicotine.
  • Relapse prevention: supports maintenance of abstinence after quitting.

How It Works

  • Nicotine in Niquitin binds to and activates nicotinic acetylcholine receptors in the central nervous system, producing a mild stimulant effect that mimics the pharmacologic action of tobacco‑derived nicotine. This receptor activation reduces the intensity of withdrawal symptoms and cravings, allowing a gradual reduction in nicotine intake while the patch provides a steady transdermal delivery over several hours.

Side Effects

Niquitin may cause a range of adverse reactions, most of which are related to the transdermal delivery system or systemic nicotine exposure.

Common Side Effects

  • Skin irritation at the application site
  • Itching or redness where the patch is applied
  • Sleep disturbance or vivid dreams
  • Nausea or upset stomach
  • Headache
  • Dizziness

Serious or Rare Side Effects

  • Severe allergic reaction (e.g., rash, swelling, hives)
  • Significant hypotension or fainting
  • Chest pain or palpitations
  • Severe skin rash or blistering
  • Respiratory difficulty
  • Unexplained syncope

Precautions & Warnings

When using Niquitin, certain precautions should be observed to ensure safety and effectiveness.

  • Cardiovascular assessment: evaluate patients with recent heart disease before initiating therapy.
  • Non‑smoker use: avoid prescribing to individuals who do not currently smoke.
  • Skin condition: do not apply to damaged, irritated, or infected skin.
  • Children: keep patches out of reach of children and pets.
  • Concomitant nicotine products: avoid using other nicotine replacement therapies simultaneously.
  • Store at room temperature: keep in the original packaging, protect from moisture and direct sunlight, and store below 25 °C.

Avoid Interactions

Niquitin can interact with several medication classes; awareness of these interactions helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Monoamine oxidase inhibitors (MAOIs): increased risk of hypertensive crisis.
  • Certain antihypertensive agents: additive blood pressure lowering effects.
  • Beta‑blockers: may exacerbate bradycardia or hypotension.

Moderate Interactions (Monitor Closely)

  • Caffeine: potential for increased nervousness or insomnia.
  • Alcohol: may enhance nicotine’s cardiovascular effects.
  • Some antidepressants (e.g., SSRIs): monitor for altered nicotine metabolism.

Frequently Asked Questions

Niquitin is a nicotine transdermal patch indicated for smoking cessation and management of nicotine dependence in adult smokers. It delivers nicotine through the skin to reduce withdrawal symptoms and cravings, supporting quit attempts.

Nicotine acts as an agonist at nicotinic acetylcholine receptors in the central nervous system. By stimulating these receptors, it mimics the effect of tobacco‑derived nicotine, decreasing withdrawal intensity and craving, thereby facilitating gradual reduction of nicotine intake.

The specific dose and duration of Niquitin are determined by the prescribing health‑care professional based on the individual’s smoking history, level of dependence, and prior quit attempts. The prescriber selects the appropriate patch strength and schedule.

Safety of nicotine patches during pregnancy or lactation has not been established. Because nicotine can cross the placenta and enter breast milk, use is generally discouraged unless the potential benefit outweighs the risk and is approved by a qualified clinician.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with nicotine gum or lozenges, the transdermal patch provides a steady, controlled release of nicotine over 16–24 hours, which can improve adherence and reduce peaks and troughs in blood nicotine levels. It is also convenient as it requires only once‑daily application, whereas gums and lozenges need multiple doses throughout the day.

Store Niquitin at room temperature, below 25 °C, in its original sealed pouch. Keep the patch away from direct sunlight, moisture and heat sources. Do not expose to temperatures above the recommended range, and keep out of reach of children.

The patch is applied to a clean, dry, hair‑free area of the upper body or upper outer arm. Press firmly for several seconds, ensuring full contact. Replace the patch according to the prescriber’s schedule, typically every 16–24 hours, and rotate application sites to avoid skin irritation.

Serious adverse reactions, though uncommon, include severe skin allergic responses, hypotension, chest pain, and dizziness that may indicate cardiovascular effects. Users should seek immediate medical attention if they experience any signs of an allergic reaction, unexplained chest discomfort, or faintness.

Niquitin is contraindicated in individuals who are not currently smokers, those with known hypersensitivity to nicotine or patch adhesives, and patients with recent myocardial infarction, unstable angina, or severe cardiac arrhythmias. It should also be avoided in pregnant or breastfeeding women unless specifically advised by a qualified health professional.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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