Product image of Nisidinasol (Paracetamol) supplied by GNH India

Nisidinasol

Active Ingredient:
Paracetamol
Origin:
EU

Nisidinasol (Paracetamol)

Paracetamol, the active ingredient in Nisidinasol, is an analgesic presented as an oral dosage form for oral use. It is commonly employed to reduce fever and relieve mild to moderate pain in adults and children when appropriate dosing is applied, and is available over‑the‑counter in many European markets.

GNH India supplies Nisidinasol as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides reliable global distribution.

Manufacturer / TM Owner

Euromed Pharma S.R.L.

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Indications & Clinical Uses

Nisidinasol, a paracetamol‑based analgesic, acts on the prostaglandin pathway to manage common pain and fever conditions.

  • Fever: helps lower elevated body temperature.
  • Headache: provides relief from tension‑type headaches.
  • Musculoskeletal pain: alleviates mild to moderate aches and strains.
  • Toothache: reduces pain associated with dental discomfort.

How It Works

  • Paracetamol exerts its effect by inhibiting cyclooxygenase enzymes, primarily COX‑2, within the central nervous system. This inhibition reduces the synthesis of prostaglandins that mediate pain and fever, leading to antipyretic and analgesic outcomes without significant peripheral anti‑inflammatory activity.

Side Effects

Paracetamol is generally well tolerated, but adverse reactions can occur.

Common Side Effects

  • Nausea: mild stomach upset.
  • Abdominal discomfort: transient discomfort in the upper abdomen.
  • Rash: mild skin redness or itching.
  • Dizziness: occasional light‑headed sensation.

Serious or Rare Side Effects

  • Hepatotoxicity: potential liver injury, especially with overdose.
  • Severe skin reactions: such as Stevens‑Johnson syndrome or toxic epidermal necrolysis.
  • Blood disorders: rare cases of thrombocytopenia or leukopenia.
  • Anaphylaxis: immediate hypersensitivity reaction requiring emergency care.

Precautions & Warnings

When using Nisidinasol, consider the following safety measures.

  • Dosage adjustment: reduce dose in patients with hepatic impairment.
  • Avoid alcohol: concurrent consumption may increase liver toxicity risk.
  • Allergy: do not use if hypersensitive to paracetamol or related compounds.
  • Pregnancy: consult a healthcare professional before use.
  • Drug interactions: review concomitant medications for potential interactions.
  • Store at ambient temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Paracetamol may interact with several medicines; monitoring is advised.

Major Interactions (Avoid)

  • Alcohol: heightened risk of liver injury.
  • Warfarin: may enhance anticoagulant effect, increasing bleeding risk.
  • Isoniazid: combined use can raise hepatotoxicity potential.

Moderate Interactions (Monitor Closely)

  • Carbamazepine: may reduce paracetamol efficacy.
  • Phenobarbital: may increase paracetamol metabolism.
  • Phenytoin: may accelerate paracetamol clearance, lowering therapeutic levels.

Frequently Asked Questions

Nisidinasol contains paracetamol and is used to lower fever and relieve mild to moderate pain such as headaches, toothaches, and musculoskeletal aches. It is an over‑the‑counter analgesic and antipyretic commonly employed in both adults and children under appropriate supervision.

Paracetamol works by inhibiting cyclooxygenase enzymes in the central nervous system, which reduces the production of prostaglandins that signal pain and raise body temperature. This central action provides analgesic and antipyretic effects without significant peripheral anti‑inflammatory activity.

The appropriate dose of Nisidinasol is determined by a qualified prescriber based on the patient’s age, weight, clinical condition, and local regulatory guidelines. Patients should follow the healthcare professional’s instructions and never exceed the recommended amount.

Paracetamol is generally considered compatible with pregnancy and lactation when used at recommended doses, but safety depends on individual circumstances. Pregnant or breastfeeding individuals should consult their healthcare provider before using Nisidinasol to ensure it is appropriate for their situation.

To order Nisidinasol, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India supplies hospitals, pharmacies, and procurement teams worldwide, and will request trade or institutional credentials before providing pricing, availability, shipping details, and any necessary import documentation.

Compared with non‑steroidal anti‑inflammatory drugs (NSAIDs), paracetamol offers analgesic and antipyretic benefits without the gastrointestinal or platelet‑inhibiting effects typical of NSAIDs. It is often preferred when anti‑inflammatory action is not required or when NSAID use is contraindicated.

Nisidinasol should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and excessive heat. Keep the product out of reach of children and avoid exposing it to direct sunlight.

Nisidinasol is taken orally, usually with a glass of water. The tablet (or other oral form) should be swallowed whole unless the prescribing information advises otherwise. It can be taken with or without food, depending on patient preference and tolerability.

The most serious risks include liver injury, especially with overdose or chronic high‑dose use, and rare severe skin reactions such as Stevens‑Johnson syndrome. Patients should avoid exceeding the recommended dose and seek immediate medical attention if they notice signs of liver dysfunction or severe rash.

Individuals with known hypersensitivity to paracetamol or any component of the formulation should avoid Nisidinasol. It should also be used with caution in patients with severe liver disease, chronic alcohol use, or those taking medications that significantly affect liver metabolism.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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