Product image of Nistatina Atb (Nystatin) supplied by GNH India

Nistatina Atb

Active Ingredient:
Nystatin
Origin:
EU

Nistatina Atb (Nystatin)

Nystatin, the active ingredient in Nistatina Atb, is an antifungal presented as a vaginal formulation for local use. It treats vaginal candidiasis by targeting fungal cells in the vaginal mucosa, providing relief of infection symptoms in adult women.

GNH India supplies Nistatina Atb as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to stringent quality standards and provides regulatory documentation to support import and clinical use. Our global logistics network ensures timely delivery to diverse healthcare settings.

Manufacturer / TM Owner

Antibiotice Sa

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Indications & Clinical Uses

Nystatin is an antifungal agent used to treat infections of the vaginal mucosa caused by Candida species.

  • Vaginal candidiasis: eradicates Candida overgrowth, relieving itching, discharge, and irritation.
  • Recurrent vulvovaginal candidiasis (maintenance therapy): reduces frequency of episodes when applied intermittently after initial treatment.
  • Candida colonization of the vaginal mucosa: lowers fungal load to prevent progression to symptomatic infection.

How It Works

  • Nystatin binds to ergosterol, a key sterol component of fungal cell membranes, forming pores that increase membrane permeability. This leads to leakage of essential intracellular ions and molecules, disrupting cellular homeostasis and ultimately causing fungal cell death without affecting human cells that lack ergosterol.

Side Effects

Nystatin is generally well tolerated when applied vaginally, but local reactions may occur.

Common Side Effects

  • Burning sensation: mild to moderate discomfort at the application site.
  • Vaginal irritation: redness or mild inflammation.
  • Increased vaginal discharge: watery or milky fluid.
  • Pruritus: transient itching.
  • Unpleasant odor: temporary change in vaginal scent.

Serious or Rare Side Effects

  • Severe allergic reaction: rash, swelling, or difficulty breathing.
  • Contact dermatitis: intense redness, swelling, or blistering.
  • Systemic absorption symptoms: nausea, vomiting, or abdominal pain (rare).
  • Persistent or worsening infection: may indicate resistance.
  • Vaginal ulceration: rare tissue breakdown.

Precautions & Warnings

Before using Nistatina Atb, consider the following safety measures.

  • Assess for hypersensitivity: discontinue if allergic signs appear.
  • Avoid use in known nystatin allergy: contraindicated.
  • Do not apply to severely inflamed or ulcerated tissue without medical advice.
  • Consult a healthcare professional if symptoms persist beyond 7 days.
  • Store at room temperature: keep in the original packaging, protect from moisture and heat.

Avoid Interactions

Nystatin has limited systemic absorption, but potential interactions should be noted.

Major Interactions (Avoid)

  • None identified: nystatin is not absorbed systemically, so no major drug interactions are expected.

Moderate Interactions (Monitor Closely)

  • Concurrent intravaginal antibiotics: may alter vaginal flora and affect nystatin efficacy.
  • Use with other topical agents: may increase local irritation.
  • Systemic antifungal therapy: may be redundant; coordinate with prescriber to avoid unnecessary overlap.

Frequently Asked Questions

Nistatina Atb is a vaginal formulation containing the antifungal agent nystatin. It is used to treat vaginal candidiasis, a yeast infection caused by Candida species, by eliminating the fungal overgrowth and relieving associated symptoms such as itching, discharge, and irritation.

Nystatin binds to ergosterol in the cell membrane of Candida fungi. This binding creates pores that increase membrane permeability, leading to leakage of essential intracellular components and ultimately causing fungal cell death while sparing human cells that lack ergosterol.

The dosage and duration of Nistatina Atb are determined by the prescribing healthcare professional based on the severity of the infection and patient-specific factors. Patients should follow the exact instructions provided by their prescriber and the product label.

Safety data for nystatin use during pregnancy and lactation are limited. Because systemic absorption from vaginal application is minimal, it is generally considered low risk, but the prescriber should evaluate the benefit‑risk balance for each individual patient.

To place an order, submit an enquiry on the product page at gnhindia.com specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details, and any necessary import documentation.

Nystatin is a polyene antifungal that acts locally with minimal systemic absorption, making it suitable for topical vaginal use. Compared with azole antifungals, it has a different mechanism of action and is less likely to interact with systemic medications, but it may be less convenient for patients who prefer oral therapy.

Store Nistatina Atb at room temperature, below 25 °C. Keep the product in its original packaging, protect it from moisture and direct heat, and ensure the container is tightly closed to maintain product stability.

Nistatina Atb is applied intravaginally. The prescribed amount is inserted into the vagina using the supplied applicator or a clean fingertip, typically once or twice daily, as directed by the healthcare professional.

The most serious risks include severe allergic reactions such as rash, swelling, or difficulty breathing, and rare systemic symptoms like nausea or vomiting if significant absorption occurs. Patients should seek immediate medical attention if any of these symptoms develop.

Individuals with a known hypersensitivity to nystatin or any component of the formulation should avoid using Nistatina Atb. Additionally, patients with extensive vaginal ulceration or severe inflammation should consult a healthcare provider before use.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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