Product image of Nisyleen (Pelargonium Sidoides Root Liquid Extraction Preparation (1 : 8-10), Extraction Solvent: Ethanol 11 %) supplied by GNH India

Nisyleen

Active Ingredient:
Pelargonium Sidoides Root Liquid Extraction Preparation (1 : 8-10), Extraction Solvent: Ethanol 11 %
Origin:
EU

Nisyleen (Pelargonium Sidoides Root Liquid Extraction Preparation (1 : 8-10), Extraction Solvent: Ethanol 11 %)

Pelargonium sidoides root extract, the active ingredient in Nisyleen, is a herbal botanical presented as a liquid oral preparation for oral use. It is traditionally employed to support respiratory health in adults with mild to moderate upper airway infections.

GNH India supplies Nisyleen as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide. The company adheres to EU quality standards and provides regulatory documentation for importers. Products are shipped in tamper‑evident containers with temperature monitoring to ensure integrity during transit.

Manufacturer / TM Owner

Vsm Geneesmiddelen Bv

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Indications & Clinical Uses

  • Nisyleen, containing Pelargonium sidoides root extract, is used primarily for conditions affecting the upper respiratory tract.
  • Acute bronchitis: supports reduction of cough frequency and may shorten the duration of symptoms.
  • Common cold: assists in relieving nasal congestion, sore throat and mild fever associated with viral upper respiratory infections.
  • Sinusitis: may improve drainage and decrease facial pressure in mild acute sinus inflammation.

How It Works

  • Pelargonium sidoides root extract exerts its activity through multiple mechanisms. It stimulates the innate immune response by enhancing macrophage activity and increasing production of interferon‑β. The extract also exhibits antimicrobial properties against common respiratory pathogens and promotes mucociliary clearance by increasing ciliary beat frequency. Additionally, it modulates inflammatory mediators, reducing excess cytokine release, which together contribute to symptom relief in respiratory infections.

Side Effects

Adverse reactions to Nisyleen are generally mild, but monitoring is advised.

Common Side Effects

  • Nausea: mild stomach upset.
  • Diarrhea: loose stools.
  • Taste disturbance: altered or bitter taste.
  • Headache: transient mild headache.

Serious or Rare Side Effects

  • Allergic reaction: rash, itching or swelling.
  • Anaphylaxis: rare systemic hypersensitivity.
  • Hepatotoxicity: occasional liver enzyme elevation.
  • Severe gastrointestinal bleeding: extremely uncommon.

Precautions & Warnings

When using Nisyleen, certain precautions should be observed to ensure safety.

  • Contraindication: avoid use in individuals with known hypersensitivity to Pelargonium sidoides.
  • Pregnancy: safety has not been established; consult a healthcare professional before use.
  • Breastfeeding: limited data; use only if benefits outweigh potential risks.
  • Pediatric use: not recommended for children under 12 years without medical advice.
  • Drug interactions: inform the prescriber of concurrent use of anticoagulants or immunosuppressants.
  • Store at ambient temperature: keep below 25 °C, protect from moisture and direct sunlight in the original container.

Avoid Interactions

Pelargonium sidoides may affect the activity of certain medicines; known interactions are summarized below.

Major Interactions (Avoid)

  • Anticoagulants (e.g., warfarin): increased risk of bleeding.
  • Immunosuppressants (e.g., cyclosporine): possible reduction of immunosuppressive effect.
  • Monoamine oxidase inhibitors: potential for hypertensive reactions.

Moderate Interactions (Monitor Closely)

  • CYP450 substrates (e.g., oral contraceptives): may alter plasma levels.
  • Antihypertensive agents: possible additive blood pressure lowering.
  • Antidiabetic drugs: monitor blood glucose for unexpected changes.

Frequently Asked Questions

Nisyleen is a liquid oral preparation containing Pelargonium sidoides root extract, traditionally used to support the respiratory system in adults experiencing mild to moderate upper respiratory tract infections such as acute bronchitis, the common cold, and sinusitis. It is not an antibiotic or vaccine but may help alleviate associated symptoms.

The extract acts through several mechanisms: it stimulates innate immune cells, increases interferon‑β production, shows mild antimicrobial activity against common respiratory pathogens, and enhances mucociliary clearance by raising ciliary beat frequency. Together these actions reduce inflammation and promote faster resolution of respiratory symptoms.

The dosage of Nisyleen is determined by the prescribing healthcare professional based on the patient’s age, weight, and clinical condition. The prescriber will specify the volume and frequency of the liquid preparation appropriate for each individual case.

Safety data for Pelargonium sidoides root extract in pregnancy and lactation are limited. Women who are pregnant, planning pregnancy, or breastfeeding should consult their physician before using Nisyleen to weigh potential benefits against unknown risks.

To place an order, submit an enquiry on the product page at gnhindia.com, indicating the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Nisyleen’s active ingredient, Pelargonium sidoides, is distinguished by documented immunomodulatory and mucolytic properties, differing from other herbal remedies such as Echinacea or elderberry that mainly target immune stimulation. Clinical studies have specifically evaluated Pelargonium sidoides for acute bronchitis, offering a more focused evidence base for this indication.

Store Nisyleen at ambient temperature, preferably below 25 °C, in its original container. Protect the bottle from direct sunlight and moisture. Keep the product out of reach of children and ensure the cap is tightly closed after each use to maintain stability.

Nisyleen is taken orally as a liquid. The prescribed volume is measured with a calibrated dropper or measuring cup provided with the product. It can be taken with or without food, following the dosing instructions given by the healthcare provider.

Although rare, serious adverse reactions may include allergic responses such as rash, swelling, or anaphylaxis, as well as liver enzyme elevations indicating potential hepatotoxicity. Patients should seek immediate medical attention if they experience signs of a severe allergic reaction or unexplained jaundice.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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