Product image of Nitradisc (Glyceryl Trinitrate) supplied by GNH India

Nitradisc

Active Ingredient:
Glyceryl Trinitrate
Origin:
EU

Nitradisc (Glyceryl Trinitrate)

Glyceryl trinitrate, the active ingredient in Nitradisc, is an organic nitrate presented as a transdermal patch for transdermal use. It acts as a vasodilator that reduces myocardial oxygen demand and is indicated for the treatment and prophylaxis of angina pectoris in patients with chronic stable angina.

GNH India supplies Nitradisc as a licensed, GDP‑compliant international pharmaceutical supplier, providing the product to hospitals, pharmacies and clinics worldwide while ensuring regulatory compliance, reliable logistics and strict quality standards for global distribution.

Manufacturer / TM Owner

Viatris Healthcare Lda.

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Nitradisc (glyceryl trinitrate) is used in the management of coronary artery disease, specifically for angina‑related conditions.

  • Angina pectoris: provides rapid relief of chest pain by dilating coronary vessels.
  • Prevention of angina attacks: maintains continuous nitrate delivery to reduce the frequency of episodes.
  • Chronic stable angina: improves exercise tolerance and reduces myocardial oxygen demand.

How It Works

  • Glyceryl trinitrate releases nitric oxide in vascular smooth muscle, activating guanylate cyclase and increasing cyclic GMP levels. The rise in cyclic GMP leads to relaxation of smooth muscle cells, causing vasodilation of veins and arteries, decreasing preload and afterload, and ultimately reducing myocardial oxygen consumption.

Side Effects

Adverse reactions to Nitradisc are generally related to its vasodilatory action and may vary in frequency and severity.

Common Side Effects

  • Headache: throbbing pain often occurring shortly after patch application.
  • Flushing: warmth and redness of the skin, especially on the face and neck.
  • Dizziness: light‑headed sensation that may be posture‑related.
  • Hypotension: mild drop in blood pressure causing faintness.

Serious or Rare Side Effects

  • Severe hypotension: marked blood pressure fall leading to syncope.
  • Reflex tachycardia: rapid heart rate in response to vasodilation.
  • Methemoglobinemia: elevated methemoglobin levels causing cyanosis.
  • Allergic skin reaction: rash, itching, or dermatitis at the patch site.

Precautions & Warnings

When prescribing Nitradisc, clinicians should consider several safety measures to minimise risks.

  • Cardiovascular assessment: evaluate baseline blood pressure and heart rate before initiating therapy.
  • Concomitant nitrates: avoid using with other nitrate preparations to prevent additive hypotension.
  • Phosphodiesterase‑5 inhibitors: do not combine with sildenafil or similar agents due to risk of severe hypotension.
  • Recent myocardial infarction: use with caution in patients who have had a recent heart attack.
  • Surgery or anesthesia: discontinue the patch prior to elective procedures to reduce intra‑operative hypotension.
  • Store at room temperature: keep below 25°C in the original pouch, protect from moisture and direct sunlight.

Avoid Interactions

Nitradisc may interact with several medicines, altering its efficacy or safety profile.

Major Interactions (Avoid)

  • Other organic nitrates: combined use can cause profound hypotension.
  • Phosphodiesterase‑5 inhibitors (e.g., sildenafil): risk of severe blood pressure reduction.
  • Guanylate cyclase stimulators: additive vasodilatory effect leading to dangerous hypotension.

Moderate Interactions (Monitor Closely)

  • Antihypertensive agents (beta‑blockers, ACE inhibitors): may enhance blood pressure‑lowering effect.
  • Diuretics: can increase risk of orthostatic hypotension.
  • Alcohol: may potentiate vasodilatory side effects such as dizziness.

Frequently Asked Questions

Nitradisc is a transdermal patch containing glyceryl trinitrate, prescribed to relieve chest pain in angina pectoris, to prevent recurrent angina attacks, and to improve exercise tolerance in patients with chronic stable angina.

Glyceryl trinitrate releases nitric oxide, which activates guanylate cyclase in vascular smooth muscle. The resulting increase in cyclic GMP causes relaxation of veins and arteries, lowering cardiac preload and afterload and reducing the heart’s oxygen demand.

The prescribed dose of Nitradisc is determined by the treating physician based on the patient’s clinical condition, severity of angina, and response to therapy. Different patch strengths may be available, and the prescriber selects the appropriate regimen.

Safety data for glyceryl trinitrate in pregnancy and lactation are limited. The product should only be used if the potential benefit justifies any possible risk to the fetus or infant, and it must be prescribed by a qualified healthcare professional.

To order Nitradisc, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Nitradisc delivers continuous nitrate therapy via a transdermal patch, offering steady plasma levels and reduced dosing frequency compared with short‑acting oral nitrates. Unlike beta‑blockers or calcium‑channel blockers, it primarily reduces preload through venous dilation, making it useful as adjunct therapy or when other agents are contraindicated.

Store Nitradisc patches at room temperature, below 25 °C, in their original sealed pouch. Protect them from moisture, direct sunlight and extreme temperatures. Keep the product out of reach of children and do not use patches that are damaged or past their expiry date.

The patch is applied to clean, dry, hair‑free skin on the upper torso or upper arm. Remove the protective liner, press the adhesive side firmly for several seconds, and replace the backing. Change the patch according to the prescriber’s schedule, typically every 24 hours, and rotate sites to avoid skin irritation.

Serious risks include severe hypotension, which can cause fainting or shock, and reflex tachycardia, a rapid heart rate triggered by sudden blood‑pressure drops. Rarely, methemoglobinemia or severe allergic skin reactions may occur; patients should seek immediate medical attention if these symptoms develop.

Nitradisc is contraindicated in patients with known hypersensitivity to glyceryl trinitrate or other organic nitrates, those who have taken phosphodiesterase‑5 inhibitors within the past 24‑48 hours, and individuals with severe anemia, increased intracranial pressure, or uncompensated heart failure unless specifically advised by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Glyceryl Trinitrate

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT