Product image of Nitrendipino Stada (Nitrendipine) supplied by GNH India

Nitrendipino Stada

Active Ingredient:
Nitrendipine
Origin:
EU

Nitrendipino Stada (Nitrendipine)

Nitrendipine, the active ingredient in Nitrendipino Stada, is a calcium channel blocker presented as an oral tablet for oral administration. It is used to lower high blood pressure in adult patients by relaxing vascular smooth muscle and reducing peripheral resistance.

GNH India supplies Nitrendipino Stada as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide, providing reliable sourcing for regulated markets with stringent quality standards and comprehensive logistics support.

Manufacturer / TM Owner

Laboratorio Stada, S.L.

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Indications & Clinical Uses

  • Nitrendipine is a calcium channel blocker used to manage conditions related to elevated vascular resistance.
  • Hypertension: Reduces systolic and diastolic blood pressure, helping to control essential hypertension.
  • Essential hypertension: Provides sustained blood‑pressure control in patients with primary hypertension.
  • Isolated systolic hypertension: Lowers elevated systolic pressure, decreasing cardiovascular risk.
  • Chronic stable angina: Improves coronary blood flow by vasodilation, relieving anginal symptoms.

How It Works

  • Nitrendipine selectively antagonizes L‑type calcium channels on vascular smooth‑muscle cells, inhibiting calcium influx. This causes relaxation of arterial smooth muscle, resulting in vasodilation, decreased peripheral vascular resistance, and ultimately a reduction in systemic blood pressure.

Side Effects

Nitrendipino Stada may cause adverse reactions; they are categorized by frequency.

Common Side Effects

  • Headache
  • Flushing
  • Peripheral edema
  • Dizziness
  • Tachycardia
  • Nausea

Serious or Rare Side Effects

  • Severe hypotension
  • Myocardial infarction
  • Hepatic dysfunction
  • Allergic reactions (rash, angioedema)
  • Cardiac arrhythmias
  • Heart block

Precautions & Warnings

  • When prescribing Nitrendipino Stada, consider the following precautions to ensure safe use.
  • Monitor blood pressure: Adjust therapy based on regular measurements.
  • Use caution in hepatic impairment: Dose may need adjustment.
  • Avoid abrupt discontinuation: Taper to prevent rebound hypertension.
  • Use with caution in heart failure: Monitor for worsening symptoms.
  • Review concomitant CYP3A4 inhibitors: May increase plasma levels.
  • Store at room temperature: Keep in original container, protect from moisture.

Avoid Interactions

Nitrendipino Stada can interact with other medicines; awareness of major and moderate interactions helps prevent adverse outcomes.

Major Interactions (Avoid)

  • Strong CYP3A4 inhibitors (e.g., ketoconazole, itraconazole)
  • Grapefruit juice
  • Concurrent use with other potent antihypertensives
  • Simultaneous use with phosphodiesterase‑5 inhibitors (e.g., sildenafil)
  • Certain antiarrhythmic agents (e.g., quinidine)

Moderate Interactions (Monitor Closely)

  • Beta‑blockers
  • Diuretics
  • ACE inhibitors
  • NSAIDs
  • Digoxin
  • Rifampin (enzyme inducer)

Frequently Asked Questions

Nitrendipino Stada is a prescription oral medication that contains nitrendipine, a calcium channel blocker indicated for the treatment of hypertension in adult patients, helping to lower elevated blood pressure.

Nitrendipine selectively blocks L‑type calcium channels in vascular smooth muscle, preventing calcium entry. This causes arterial relaxation, vasodilation, and a reduction in peripheral vascular resistance, which lowers systemic blood pressure.

The dosage is individualized; the prescribing physician determines the appropriate strength and regimen based on the patient’s clinical condition, response, and tolerability.

Safety in pregnancy and lactation has not been established. It should only be used if the potential benefit justifies the potential risk to the fetus or infant, and the decision must be made by a qualified health professional.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and required import documentation.

Both are dihydropyridine calcium channel blockers for hypertension, but nitrendipine has a shorter half‑life and may require once‑daily dosing, whereas amlodipine’s longer duration often allows once‑daily dosing with a different side‑effect profile, such as a lower incidence of peripheral edema.

Store at room temperature, below 25 °C, in the original packaging, protected from moisture and direct sunlight to maintain product stability.

The medication is taken orally, usually with or without food, as directed by the prescriber. Swallow the tablet whole with a glass of water; do not crush or chew unless specifically instructed.

Serious adverse events include severe hypotension, myocardial infarction, hepatic dysfunction, life‑threatening allergic reactions, and cardiac arrhythmias. Seek immediate medical attention if symptoms such as fainting, chest pain, severe dizziness, or rash occur.

Individuals with known hypersensitivity to nitrendipine or any component of the formulation, patients with severe aortic stenosis, uncontrolled heart failure, or those taking contraindicated strong CYP3A4 inhibitors should avoid this medication unless a physician determines it is safe.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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