Nitrofurantoin Iasis Pharma

Active Ingredient:: Nitrofurantoin
Origin:: EU

Nitrofurantoin Iasis Pharma (Nitrofurantoin)

Q: What is Nitrofurantoin Iasis Pharma used for?

Nitrofurantoin Iasis Pharma is an oral nitrofuran antibiotic indicated for the treatment of uncomplicated urinary tract infections, including acute cystitis, and may be prescribed for prophylaxis of recurrent urinary tract infections when appropriate.

Q: How does Nitrofurantoin work?

Nitrofurantoin inhibits bacterial enzyme systems that are essential for carbohydrate metabolism and cell‑wall synthesis. This action results in bactericidal activity that is concentrated in the urinary tract, where the drug reaches therapeutic concentrations to eliminate susceptible pathogens.

Q: What is the usual dose of Nitrofurantoin Iasis Pharma?

The dosage regimen is set by the prescribing clinician based on the type of infection, the patient’s renal function, and local treatment guidelines. Patients should follow the prescriber’s instructions and the product label precisely.

Q: Is Nitrofurantoin safe in pregnancy or breastfeeding?

Safety data are limited; the product is classified as pregnancy category unknown and is generally avoided in the third trimester. Women who are pregnant, planning pregnancy, or breastfeeding should discuss potential risks and alternative therapies with their healthcare provider.

Q: How do I order Nitrofurantoin Iasis Pharma from GNH India?

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Q: How does Nitrofurantoin compare with other urinary antiseptics?

Compared with agents such as trimethoprim‑sulfamethoxazole, nitrofurantoin has a narrower spectrum focused on common uropathogens and achieves high urinary concentrations, limiting systemic exposure. Resistance patterns, renal function and patient tolerance often guide the choice between these agents.

Q: How should Nitrofurantoin Iasis Pharma be stored?

Store the product below 25 °C in its original packaging, protected from moisture and direct sunlight. Keep the container tightly closed and out of reach of children to maintain stability and potency.

Q: How is Nitrofurantoin administered?

Nitrofurantoin Iasis Pharma is taken orally, usually with food or milk to reduce gastrointestinal irritation. Swallow tablets whole with a full glass of water; do not crush or chew unless specifically instructed by a healthcare professional.

Q: What are the most serious risks to watch for with Nitrofurantoin?

Rare but serious adverse reactions include pulmonary toxicity, severe liver injury, hemolytic anemia in patients with G6PD deficiency, and life‑threatening allergic reactions such as anaphylaxis. Seek immediate medical attention if you experience shortness of breath, rash, jaundice, or dark urine.

Q: Who should not use Nitrofurantoin Iasis Pharma?

Patients with severe renal impairment (creatinine clearance <30 mL/min), known hypersensitivity to nitrofurantoin, G6PD deficiency, or those in the third trimester of pregnancy should avoid this medication. Clinicians must evaluate each patient’s medical history before prescribing.

Nitrofurantoin, the active ingredient in Nitrofurantoin Iasis Pharma, is a nitrofuran antibiotic presented as an oral dosage form for oral use. It treats uncomplicated urinary tract infections and may be used for prophylaxis of recurrent infections in appropriate patients.

GNH India supplies Nitrofurantoin Iasis Pharma as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Iasis Pharma

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Indications & Clinical Uses

Nitrofurantoin Iasis Pharma is a nitrofuran antibiotic used to manage infections of the urinary tract.

Uncomplicated urinary tract infection: eradicates susceptible bacteria causing bladder infection.
Acute cystitis: provides rapid bactericidal activity to resolve bladder infection symptoms.
Prophylaxis of recurrent urinary tract infection: reduces the frequency of future infections when taken as preventive therapy.

How It Works

Nitrofurantoin exerts its antibacterial effect by inhibiting bacterial enzyme systems involved in carbohydrate metabolism and cell‑wall synthesis. This disruption leads to bactericidal activity that is concentrated in the urinary tract, where the drug achieves therapeutic levels sufficient to eliminate susceptible uropathogens.

Side Effects

Nitrofurantoin may cause a range of adverse reactions.

Common Side Effects

Nausea: mild to moderate stomach upset.
Loss of appetite: reduced desire to eat.
Headache: transient cranial discomfort.
Diarrhea: loose stools, often self‑limiting.
Metallic taste: transient alteration of taste perception.
Rash: mild skin irritation or erythema.

Serious or Rare Side Effects

Pulmonary toxicity: interstitial lung disease or acute respiratory distress.
Hepatic injury: elevated liver enzymes or hepatitis.
Hemolytic anemia in G6PD deficiency: rapid destruction of red blood cells.
Severe allergic reaction: anaphylaxis or angioedema.
Peripheral neuropathy: tingling or numbness in extremities.
Stevens‑Johnson syndrome: severe skin blistering and mucosal involvement.

Precautions & Warnings

Before prescribing Nitrofurantoin Iasis Pharma, clinicians should consider several safety factors.

Renal function assessment: avoid use in patients with creatinine clearance <30 mL/min.
G6PD deficiency: contraindicated due to risk of hemolysis.
Pregnancy trimester: avoid in late (third) pregnancy.
Monitor pulmonary symptoms: discontinue if respiratory distress develops.
Hepatic impairment: use with caution in severe liver disease.
Store below 25°C: keep in the original pack, protect from moisture and direct sunlight.

Avoid Interactions

Nitrofurantoin Iasis Pharma can interact with other medicines, requiring attention to avoid reduced efficacy or increased toxicity.

Major Interactions (Avoid)

Antacids containing magnesium or aluminum: decrease nitrofurantoin absorption.
Probenecid: increases nitrofurantoin plasma levels, raising toxicity risk.
Warfarin: may enhance anticoagulant effect, increasing bleeding risk.

Moderate Interactions (Monitor Closely)

Fluoroquinolones: additive gastrointestinal upset.
Non‑steroidal anti‑inflammatory drugs (NSAIDs): potential renal function impact.
Diuretics: may alter urinary concentration, affecting drug efficacy.

Frequently Asked Questions

Nitrofurantoin Iasis Pharma is an oral nitrofuran antibiotic indicated for the treatment of uncomplicated urinary tract infections, including acute cystitis, and may be prescribed for prophylaxis of recurrent urinary tract infections when appropriate.

Nitrofurantoin inhibits bacterial enzyme systems that are essential for carbohydrate metabolism and cell‑wall synthesis. This action results in bactericidal activity that is concentrated in the urinary tract, where the drug reaches therapeutic concentrations to eliminate susceptible pathogens.

The dosage regimen is set by the prescribing clinician based on the type of infection, the patient’s renal function, and local treatment guidelines. Patients should follow the prescriber’s instructions and the product label precisely.

Safety data are limited; the product is classified as pregnancy category unknown and is generally avoided in the third trimester. Women who are pregnant, planning pregnancy, or breastfeeding should discuss potential risks and alternative therapies with their healthcare provider.

Submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Compared with agents such as trimethoprim‑sulfamethoxazole, nitrofurantoin has a narrower spectrum focused on common uropathogens and achieves high urinary concentrations, limiting systemic exposure. Resistance patterns, renal function and patient tolerance often guide the choice between these agents.

Store the product below 25 °C in its original packaging, protected from moisture and direct sunlight. Keep the container tightly closed and out of reach of children to maintain stability and potency.

Nitrofurantoin Iasis Pharma is taken orally, usually with food or milk to reduce gastrointestinal irritation. Swallow tablets whole with a full glass of water; do not crush or chew unless specifically instructed by a healthcare professional.

Rare but serious adverse reactions include pulmonary toxicity, severe liver injury, hemolytic anemia in patients with G6PD deficiency, and life‑threatening allergic reactions such as anaphylaxis. Seek immediate medical attention if you experience shortness of breath, rash, jaundice, or dark urine.

Patients with severe renal impairment (creatinine clearance <30 mL/min), known hypersensitivity to nitrofurantoin, G6PD deficiency, or those in the third trimester of pregnancy should avoid this medication. Clinicians must evaluate each patient’s medical history before prescribing.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated: 27 Sep 2026

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