Product image of Nitrolingual Infus (Glyceryl Trinitrate) supplied by GNH India

Nitrolingual Infus

Active Ingredient:
Glyceryl Trinitrate
Origin:
EU

Nitrolingual Infus (Glyceryl Trinitrate)

Glyceryl Trinitrate, the active ingredient in Nitrolingual Infus, is an organic nitrate presented as an intravenous solution for intravenous use. It is employed to relieve acute angina, support heart failure management, and treat hypertensive emergencies in adult patients.
GNH India supplies Nitrolingual Infus as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals worldwide.

Manufacturer / TM Owner

G. Pohl-Boskamp Gmbh Co. Kg

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Nitrolingual Infus is an organic nitrate used in cardiovascular conditions where rapid vasodilation is required.

  • Acute angina pectoris: provides prompt relief of chest pain by dilating coronary arteries.
  • Heart failure: reduces preload and afterload, improving cardiac output in decompensated states.
  • Hypertensive emergencies: lowers systemic vascular resistance to rapidly control severe blood pressure elevations.

How It Works

  • Glyceryl Trinitrate is metabolized to nitric oxide, which activates guanylate cyclase in vascular smooth muscle cells. The resulting increase in cyclic GMP leads to relaxation of smooth muscle, causing dilation of veins and arteries, reduced cardiac preload and afterload, and improved myocardial oxygen delivery.

Side Effects

Nitrolingual Infus may cause a range of adverse reactions, from mild to severe.

Common Side Effects

  • Headache: throbbing pain often described as a “nitroglycerin headache.”
  • Flushing: warm sensation and redness of the skin.
  • Hypotension: transient drop in blood pressure, especially with rapid infusion.
  • Tachycardia: compensatory increase in heart rate.
  • Nausea: mild gastrointestinal upset.
  • Dizziness: feeling light‑headed or unsteady.

Serious or Rare Side Effects

  • Severe hypotension: marked blood pressure fall leading to syncope.
  • Methemoglobinemia: impaired oxygen delivery due to altered hemoglobin.
  • Allergic reaction: rash, pruritus, or anaphylaxis.
  • Reflex angina: chest pain recurrence due to rapid blood pressure changes.
  • Cardiac arrhythmias: abnormal heart rhythms in susceptible patients.
  • Pulmonary edema: fluid accumulation in lungs, rarely reported.

Precautions & Warnings

Before using Nitrolingual Infus, clinicians should assess patient history and monitor vital signs closely.

  • Blood pressure monitoring: check baseline and during infusion to avoid excessive hypotension.
  • Concomitant nitrates: avoid simultaneous use with other nitrate preparations to prevent severe hypotension.
  • Phosphodiesterase‑5 inhibitors: do not co‑administer with sildenafil, tadalafil, or similar agents.
  • Cardiovascular instability: use with caution in patients with recent myocardial infarction or unstable angina.
  • Storage: Store below 25°C: keep in the original container, protect from moisture and light.

Avoid Interactions

Nitrolingual Infus can interact with several drug classes, requiring careful management.

Major Interactions (Avoid)

  • Phosphodiesterase‑5 inhibitors: may cause profound hypotension.
  • Other organic nitrates: additive vasodilatory effect leading to dangerous blood pressure drops.
  • Antihypertensive agents (e.g., ACE inhibitors, ARBs): can amplify blood pressure lowering.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: may mask tachycardia signs of hypotension.
  • Diuretics: combined effect on volume status may increase hypotensive risk.
  • Calcium channel blockers: additive vasodilatory action.
  • Alcohol: can enhance vasodilatory response and dizziness.

Frequently Asked Questions

Nitrolingual Infus, containing Glyceryl Trinitrate, is prescribed for the rapid relief of acute angina pectoris, for managing decompensated heart failure, and for controlling severe blood pressure spikes in hypertensive emergencies. It works by dilating blood vessels to improve cardiac blood flow and reduce cardiac workload.

Glyceryl Trinitrate is converted to nitric oxide after administration. Nitric oxide activates the enzyme guanylate cyclase, increasing cyclic GMP levels in vascular smooth muscle. This cascade relaxes the muscle, causing veins and arteries to widen, which lowers blood pressure and eases the heart’s effort to pump blood.

The specific dose and infusion rate of Nitrolingual Infus are determined by the treating physician based on the patient’s clinical condition, response, and safety considerations. Healthcare providers tailor the regimen to achieve the desired hemodynamic effect while monitoring for adverse reactions.

Safety data for Glyceryl Trinitrate in pregnancy and lactation are limited. It should only be used if the potential benefit justifies any possible risk to the fetus or infant, and the decision must be made by a qualified healthcare professional after a thorough risk‑benefit assessment.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details (including any cold‑chain needs), and required import documentation.

Nitrolingual Infus belongs to the organic nitrate class, offering rapid onset of vasodilation via nitric oxide release. Compared with beta‑blockers or calcium‑channel blockers, nitrates act directly on vascular smooth muscle, providing quicker symptom relief but requiring careful blood pressure monitoring and avoidance of concurrent nitrate use.

Nitrolingual Infus should be stored below 25 °C, in its original packaging, protected from moisture and light. Maintaining a stable temperature helps preserve the drug’s potency and prevents degradation of the nitrate solution.

The product is supplied for intravenous administration. It is typically diluted in an appropriate carrier solution and infused slowly under continuous hemodynamic monitoring, allowing clinicians to adjust the rate based on blood pressure and symptom response.

The most critical risks include severe hypotension that can lead to syncope, reflex tachycardia, and rare cases of methemoglobinemia. Prompt recognition and immediate management of these events are essential, especially when the drug is used with other vasodilators.

Patients with known hypersensitivity to Glyceryl Trinitrate or any organic nitrate, those who have taken phosphodiesterase‑5 inhibitors within the past 24‑48 hours, and individuals with severe hypotension or uncompensated shock should not be given Nitrolingual Infus. Clinical judgment is required for each case.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Related Products

Other formulations containing Glyceryl Trinitrate

A

A
A

A
A

A
A

A

Browse all products →

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Regulatory recognitions

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.

SGS GSDP Certification

GSDP Compliant from SGS

URS ISO 9001

URS ISO 9001 Certification

FDA Maharashtra

Licensed by FDA Maharashtra

IEC License DGFT

IEC License issued by DGFT