Product image of Nitrolingual Pompspray (Glyceryl Trinitrate) supplied by GNH India

Nitrolingual Pompspray

Active Ingredient:
Glyceryl Trinitrate
Origin:
EU

Nitrolingual Pompspray (Glyceryl Trinitrate)

Glyceryl trinitrate, the active ingredient in Nitrolingual Pompspray, is a organic nitrate presented as an oral spray for oromucosal use. It is used to relieve acute angina pectoris and to prevent angina attacks in patients with coronary artery disease.
GNH India supplies Nitrolingual Pompspray as a licensed, GDP‑compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

G. Pohl-Boskamp Gmbh Co. Kg

1
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Indications & Clinical Uses

  • Nitrolingual Pompspray belongs to the organic nitrate class and is used in the management of angina-related conditions.
  • Acute angina pectoris: rapid relief of chest pain through coronary vasodilation.
  • Prophylaxis of angina attacks: prevention of recurrent episodes by reducing myocardial oxygen demand.
  • Exercise‑induced angina: mitigation of pain during physical exertion by maintaining coronary blood flow.

How It Works

  • Glyceryl trinitrate releases nitric oxide in vascular smooth muscle, activating guanylate cyclase and increasing cyclic GMP levels. The rise in cyclic GMP leads to relaxation of smooth muscle in veins and arteries, producing venodilation and arterial dilation, which lowers preload and afterload and reduces myocardial oxygen consumption.

Side Effects

Nitrolingual Pompspray may cause several adverse reactions, ranging from mild to serious.

Common Side Effects

  • Headache
  • Flushing
  • Dizziness
  • Hypotension

Serious or Rare Side Effects

  • Severe hypotension leading to syncope
  • Methemoglobinemia
  • Allergic reactions such as rash or bronchospasm

Precautions & Warnings

  • Before prescribing Nitrolingual Pompspray, consider the following safety measures.
  • Avoid use in patients with severe hypotension: risk of further blood pressure drop.
  • Do not combine with phosphodiesterase‑5 inhibitors: may cause profound hypotension.
  • Monitor blood pressure after the first dose: ensure patient tolerates the effect.
  • Use caution in patients with anemia or recent myocardial infarction: altered oxygen delivery.
  • Store at room temperature: keep in the original container, protect from moisture and light.

Avoid Interactions

Nitrolingual Pompspray can interact with several drug classes; awareness of these interactions helps prevent adverse events.

Major Interactions (Avoid)

  • Sildenafil, tadalafil, or other PDE5 inhibitors: risk of severe hypotension.
  • Other nitrates (e.g., isosorbide dinitrate): additive vasodilatory effect.
  • Sodium nitroprusside: excessive blood pressure reduction.

Moderate Interactions (Monitor Closely)

  • Beta‑blockers: may mask tachycardia response.
  • Calcium channel blockers: additive blood pressure lowering.
  • Alcohol: enhances hypotensive effect.

Frequently Asked Questions

Nitrolingual Pompspray contains glyceryl trinitrate and is prescribed to relieve acute angina pectoris and to prevent future angina attacks in patients with coronary artery disease. It works by dilating coronary vessels, improving blood flow to the heart muscle.

Glyceryl trinitrate releases nitric oxide, which activates guanylate cyclase in vascular smooth muscle. This raises cyclic GMP levels, causing relaxation of veins and arteries, reducing cardiac preload and afterload, and lowering myocardial oxygen demand.

The specific dose and frequency of Nitrolingual Pompspray are determined by the prescribing clinician based on the patient’s condition, severity of angina, and response to therapy. Patients should follow the prescriber’s instructions and not adjust the dose on their own.

Safety data for glyceryl trinitrate in pregnancy and lactation are limited. The product should only be used if the potential benefit justifies any potential risk to the fetus or infant, and this decision must be made by a qualified healthcare professional.

To place an order, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Nitrolingual Pompspray is an organic nitrate, offering rapid onset of action via oromucosal delivery. Compared with oral tablets, the spray provides quicker relief, while other classes such as beta‑blockers or calcium‑channel blockers act through different mechanisms and may be used in combination for comprehensive angina management.

Store Nitrolingual Pompspray at room temperature, below 25 °C, in its original packaging. Keep the container tightly closed, protect it from moisture and direct sunlight, and avoid freezing to maintain product stability.

The spray is applied to the oral mucosa, typically under the tongue or inside the cheek, as directed by the prescriber. The patient should avoid swallowing immediately, allowing the medication to absorb through the mucous membranes for rapid effect.

Serious risks include severe hypotension, syncope, methemoglobinemia, and allergic reactions such as rash or bronchospasm. Patients should be monitored for these events, especially when initiating therapy or when used with other vasodilators.

Nitrolingual Pompspray should be avoided in patients with known hypersensitivity to glyceryl trinitrate or other nitrates, those with severe hypotension, and individuals concurrently using phosphodiesterase‑5 inhibitors unless specifically directed by a physician.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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