Product image of Nitromint (Glyceryl Trinitrate) supplied by GNH India

Nitromint

Active Ingredient:
Glyceryl Trinitrate
Origin:
EU

Nitromint (Glyceryl Trinitrate)

Glyceryl trinitrate, the active ingredient in Nitromint, is a nitrate vasodilator presented as an oral formulation for oral use. It treats angina pectoris and related cardiac conditions in adults.

GNH India supplies Nitromint as a licensed, GDP-compliant international pharmaceutical supplier serving hospitals, pharmacies and clinics worldwide.

Manufacturer / TM Owner

Egis Pharmaceuticals Plc

1
Pack/s
This product is added to your enquiry list

Request a Quote

Please fill out the form below and our team will get back to you shortly with pricing and further information.

A minimum order value applies. Our team will confirm the exact amount or quantity after reviewing your requirements.

Indications & Clinical Uses

Nitromint (glyceryl trinitrate) is used in the management of coronary artery disease and related conditions.

  • Angina pectoris: relieves chest pain by improving myocardial oxygen supply.
  • Acute coronary syndrome: reduces cardiac workload during acute events.
  • Heart failure: alleviates symptoms by decreasing preload and afterload.

How It Works

  • Glyceryl trinitrate is enzymatically converted to nitric oxide within vascular smooth muscle. The released nitric oxide activates soluble guanylate cyclase, raising cyclic GMP levels, which cause relaxation of venous and arterial smooth muscle. This vasodilation lowers preload and afterload, reducing myocardial oxygen demand and improving coronary blood flow.

Side Effects

Nitromint may cause several adverse reactions, ranging from mild to serious.

Common Side Effects

  • Headache: throbbing pain often triggered by vasodilation.
  • Dizziness: sensation of light‑headedness due to lowered blood pressure.
  • Flushing: warmth and redness of the skin, especially on the face.
  • Hypotension: measurable drop in systolic or diastolic pressure.
  • Nausea: upset stomach, sometimes accompanied by vomiting.
  • Tachycardia: compensatory increase in heart rate.

Serious or Rare Side Effects

  • Severe hypotension: marked blood pressure fall leading to fainting.
  • Syncope: sudden loss of consciousness.
  • Myocardial infarction: rare occurrence of heart attack.
  • Methemoglobinemia: abnormal hemoglobin causing reduced oxygen delivery.
  • Allergic reaction: rash, itching, swelling, or anaphylaxis.
  • Tolerance development: diminished response requiring dose escalation.

Precautions & Warnings

Before prescribing Nitromint, clinicians should consider several safety measures.

  • Monitor blood pressure: check for excessive drops after dosing.
  • Avoid concurrent nitrates: combined use can cause profound hypotension.
  • Caution with phosphodiesterase‑5 inhibitors: contraindicated within 24–48 hours.
  • Assess anemia or hypovolemia: patients with low hemoglobin may be more susceptible to hypotension.
  • Do not discontinue abruptly: tapering may be needed to avoid rebound angina.
  • Store at ambient temperature: keep below 25 °C in the original pack, protect from moisture.

Avoid Interactions

Nitromint can interact with several drug classes, requiring careful management.

Major Interactions (Avoid)

  • Phosphodiesterase‑5 inhibitors (e.g., sildenafil): risk of severe hypotension.
  • Other nitrates (e.g., isosorbide dinitrate): additive vasodilatory effect.
  • Guanylate cyclase stimulators: may amplify blood pressure reduction.

Moderate Interactions (Monitor Closely)

  • Antihypertensives (e.g., ACE inhibitors, ARBs): may enhance blood pressure lowering.
  • Diuretics: can increase risk of volume depletion and hypotension.
  • Beta‑blockers: may mask tachycardia signs of hypotension.
  • Certain antiretrovirals (e.g., ritonavir): may affect nitrate metabolism.
  • Azole antifungals (e.g., ketoconazole): potential pharmacokinetic interaction.

Frequently Asked Questions

Nitromint contains glyceryl trinitrate, a nitrate vasodilator prescribed for the relief and prevention of angina pectoris, management of acute coronary syndrome, and symptomatic treatment of heart failure. It works by dilating coronary and peripheral vessels, improving oxygen delivery to the myocardium. Use is determined by a qualified healthcare professional based on individual cardiac condition.

Glyceryl trinitrate is metabolized to nitric oxide in vascular smooth muscle. Nitric oxide activates soluble guanylate cyclase, increasing cyclic guanosine monophosphate (cGMP). Elevated cGMP causes relaxation of smooth muscle, producing venous and arterial dilation, reducing preload and afterload, and lowering myocardial oxygen demand, which alleviates ischemic chest pain.

The specific dose of Nitromint is individualized by the prescribing clinician. Dosage may be adjusted according to the severity of angina, patient tolerance, and response to therapy. Patients should follow the exact regimen provided on the prescription label and consult their healthcare provider for any adjustments.

The safety of glyceryl trinitrate in pregnancy and lactation has not been definitively established, and it is generally classified as a category where risk cannot be ruled out. Healthcare providers will weigh potential benefits against possible risks before prescribing to pregnant or nursing individuals. Use only if clearly indicated.

To request Nitromint, visit the product page on gnhindia.com, enter the desired quantity, and submit the inquiry form. GNH India works with hospitals, pharmacies, and procurement teams worldwide, verifying trade or institutional credentials before providing pricing, availability, shipping details, and any required import documentation.

Nitromint (glyceryl trinitrate) belongs to the nitrate class, providing rapid vasodilation and relief of acute chest pain, whereas beta‑blockers reduce heart rate and contractility, and calcium‑channel blockers primarily affect arterial tone. Nitrates are often used for immediate symptom control, while other agents are used for long‑term prevention; choice depends on clinical context.

Nitromint should be stored at ambient temperature, below 25 °C, in its original packaging to protect it from moisture and light. Keep the product out of reach of children and avoid storing in areas with high humidity or extreme temperatures, which could affect its stability and efficacy.

Nitromint is taken orally as directed by a healthcare professional. The tablet (or sublingual form if applicable) is placed under the tongue or swallowed, depending on the specific product formulation and the prescriber's instructions. Administration should occur on an empty stomach for optimal absorption, and patients should avoid crushing or chewing unless advised.

The most serious adverse reactions to Nitromint include severe hypotension, syncope, and rare cases of myocardial infarction or methemoglobinemia. Patients should be monitored for sudden drops in blood pressure, dizziness, or chest discomfort, and seek immediate medical attention if these symptoms occur. Prompt reporting of any severe side effects is essential.

Nitromint is contraindicated in individuals with known hypersensitivity to glyceryl trinitrate or other nitrates, patients who have taken phosphodiesterase‑5 inhibitors (e.g., sildenafil) within the past 24–48 hours, and those with severe anemia, increased intracranial pressure, or uncompensated heart failure. Clinicians must assess each patient’s medical history before prescribing.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

Disclaimer

At GNH India, we aim to provide information that is expert-reviewed, accurate, and reliable. However, all content on this platform is intended for general informational purposes only and does not constitute professional medical advice, diagnosis, or treatment. While efforts are made to maintain accuracy and currency, the information may contain errors, omissions, or may not reflect the latest developments. Always consult a qualified healthcare professional regarding any medical concerns.

All product names, brand names, trademarks and registered trademarks displayed on this website are the property of their respective owners. This website and its operator are not affiliated with, endorsed by, or authorized by any such trade mark owners unless expressly stated. Any reference to product names or trademarks is made solely for descriptive and informational purposes. No commercial relationship, sponsorship, approval, or association with any trademark owner should be inferred. Information provided herein does not constitute promotion, advertising, or an offer for sale of any medicinal product and is intended solely for general informational purposes.

All trademarks and brand names displayed on this website are used strictly in accordance with the provisions of the Trade Marks Act, 1999, specifically Sections 30 and 30(1) governing fair use. Trademark ownership has been accurately attributed under the "Manufacturer/ TM Owner" section in compliance with statutory requirements.

Ordering Process

Simple, Secure, and Seamless

Learn how our streamlined ordering process guarantees fast, compliant, and reliable access to essential medicines worldwide.

Quote request form

01

Submit Quote Request Form

Tell us what medications you need by filling out our simple form and uploading a valid document.

Price estimate review

02

We Review & Send Estimate

Our licensed pharmacists will verify your details and provide you with a detailed cost estimate.

Secure payment

03

Confirm & Make Payment

Discuss any queries, approve the estimate, and complete your payment.

Worldwide delivery

04

Get Delivered

Your medicines, safely packed and delivered to your door or nearest airport — hassle-free.

Quality You Can Trust

Our internationally recognized certifications underscore our commitment to safety, quality, and excellence.