Product image of Nixar (Bilastine) supplied by GNH India

Nixar

Active Ingredient:
Bilastine
Origin:
EU

Nixar (Bilastine)

Bilastine, the active ingredient in Nixar, is an antihistamine presented as an oral tablet for oral use. It alleviates symptoms of allergic rhinitis and chronic idiopathic urticaria in adults and adolescents by blocking peripheral H1 receptors, and is available without prescription in many EU countries.

GNH India supplies Nixar as a licensed, GDP‑compliant international pharmaceutical product, adhering to EU quality standards and regulatory requirements. The company serves hospitals, pharmacies and clinics worldwide, providing reliable sourcing, batch traceability and support for procurement teams across multiple markets.

Manufacturer / TM Owner

Menarini International Operations Luxembourg S.A.

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Indications & Clinical Uses

  • Bilastine is an antihistamine that acts on the histamine H1‑receptor pathway to relieve allergic conditions.
  • Allergic rhinitis: reduces nasal congestion, itching, sneezing and rhinorrhea.
  • Chronic idiopathic urticaria: decreases wheal formation and itching associated with hives.
  • Allergic rhinoconjunctivitis: alleviates ocular itching, redness and watery discharge.

How It Works

  • Bilastine selectively antagonizes peripheral H1 histamine receptors, preventing histamine from binding and triggering the cascade that leads to vasodilation, increased vascular permeability, and sensory nerve activation. By blocking this pathway, it mitigates the classic symptoms of allergic reactions without significant central nervous system penetration, resulting in minimal sedation.

Side Effects

Bilastine is generally well tolerated, but some patients may experience adverse reactions.

Common Side Effects

  • Headache
  • Mild drowsiness
  • Dry mouth
  • Fatigue
  • Gastrointestinal discomfort (nausea, abdominal pain)
  • Dizziness

Serious or Rare Side Effects

  • Anaphylactic reaction
  • Severe cutaneous adverse reactions (e.g., Stevens‑Johnson syndrome)
  • Cardiac arrhythmias
  • Hepatic injury
  • Angioedema
  • Severe hypotension

Precautions & Warnings

Before using Nixar, consider the following precautions.

  • Pregnancy: consult a healthcare professional; data are limited.
  • Breastfeeding: use with caution as the drug may be excreted in milk.
  • Renal impairment: dose adjustment may be required in severe cases.
  • Elderly patients: monitor for increased sedation or dizziness.
  • Concomitant drugs: review potential interactions, especially with strong CYP inhibitors.
  • Store at ambient temperature: keep in the original pack, protect from moisture and heat.

Avoid Interactions

Bilastine may interact with several medicines; monitoring is advised.

Major Interactions (Avoid)

  • Ketoconazole: can raise bilastine plasma concentrations.
  • Erythromycin: may increase systemic exposure.
  • Ritonavir: strong CYP3A4 inhibitor that elevates levels.
  • Antacids containing aluminum or magnesium: reduce oral absorption.

Moderate Interactions (Monitor Closely):\n- Alcohol: may enhance drowsiness.

  • Other antihistamines: additive sedation possible.
  • Central nervous system depressants (e.g., benzodiazepines): monitor for excessive sedation.

Frequently Asked Questions

Nixar contains bilastine, an antihistamine indicated for the relief of symptoms associated with allergic rhinitis and chronic idiopathic urticaria. It helps reduce nasal congestion, sneezing, itching, and hives by blocking the action of histamine at peripheral H1 receptors.

Bilastine works as a selective peripheral H1‑receptor antagonist. By binding to H1 receptors on blood vessels and sensory nerves, it prevents histamine from triggering vasodilation, increased permeability, and nerve stimulation, thereby reducing the classic signs of an allergic response.

The dose of Nixar is determined by the prescribing healthcare professional. In most adult patients, a single oral tablet taken once daily is typical, but the exact regimen should follow the prescriber’s instructions and local labeling.

Safety data for bilastine during pregnancy are limited, so it should only be used if the potential benefit outweighs any risk. While breastfeeding, caution is advised because the drug may be excreted in breast milk; a healthcare provider should evaluate the need for treatment.

To order Nixar, submit an enquiry on the product page at gnhindia.com, specifying the required quantity. GNH India works with hospitals, pharmacies and procurement teams worldwide, verifies trade or institutional credentials, and then provides pricing, availability, shipping details and any necessary import documentation.

Bilastine offers a non‑sedating profile compared with first‑generation antihistamines and has comparable efficacy to other second‑generation agents such as cetirizine or loratadine. Its selective peripheral action reduces central nervous system penetration, making it a suitable option for patients who need minimal drowsiness.

Nixar tablets should be stored at ambient temperature, below 25 °C. Keep them in the original packaging, protect from moisture and direct sunlight, and ensure the container is tightly closed to maintain product stability.

Nixar is taken orally, usually as a whole tablet with water. It can be taken with or without food, but should be swallowed whole and not chewed or crushed to ensure proper absorption.

Although rare, serious adverse reactions may include anaphylaxis, severe skin reactions such as Stevens‑Johnson syndrome, angioedema, cardiac arrhythmias, and significant liver injury. Patients should seek immediate medical attention if they experience symptoms like swelling of the face or throat, rash, or unexplained dizziness.

Nixar should be avoided in individuals with known hypersensitivity to bilastine or any tablet excipients. Caution is also advised for patients with severe renal impairment, pregnant or breastfeeding women unless directed by a physician, and those taking medications that strongly increase bilastine levels.

Published by

GNH India Pharmaceuticals Limited

Licensed pharmaceutical supplier

Last updated:

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